Outbreak of Burkholderia cepacia complex caused by contaminated alcohol-free mouthwash;Ausbruch mit Burkholderia-cepacia-komplex durch kontaminierte mundspüllösung

Anaesthesist

Volumn 61, Issue 1, 2012, Pages 25-29

  Martin, M ^a,b   Winterfeld, I ^b,c   Kramme, E ^b   Ewert, I ^b   Sedemund Adib, B ^b   Mattner, F ^b,c  

^a UNIVERSITY OF FREIBURG   (Germany)

^b UNIVERSITY OF LÜBECK   (Germany)

^c UNIVERSITY OF WITTEN HERDECKE   (Germany)

Author keywords

Alcohol free; Antiseptics; Intensive care units; Mouthwashes; Pneumonia, ventilator associated

Indexed keywords

ALCOHOL FREE MOUTHWASH; HEXETIDINE; MOUTHWASH; UNCLASSIFIED DRUG;

ARTICLE; BACTERIUM ISOLATE; BURKHOLDERIA CEPACIA COMPLEX; BURKHOLDERIA CEPACIA INFECTION; CLINICAL ARTICLE; CONTAMINATION; GERMANY; HUMAN; INTENSIVE CARE UNIT; MOUTH CAVITY; NONHUMAN; PULSED FIELD GEL ELECTROPHORESIS; UNIVERSITY HOSPITAL; VENTILATOR ASSOCIATED PNEUMONIA;

ADULT; AGED; AGED, 80 AND OVER; ANTI-INFECTIVE AGENTS, LOCAL; BRONCHOALVEOLAR LAVAGE FLUID; BURKHOLDERIA CEPACIA COMPLEX; BURKHOLDERIA INFECTIONS; CROSS INFECTION; DATABASES, FACTUAL; DISEASE OUTBREAKS; DRUG CONTAMINATION; DRUG RECALLS; ELECTROPHORESIS, GEL, PULSED-FIELD; FEMALE; HEXETIDINE; HUMANS; INTENSIVE CARE UNITS; MALE; MIDDLE AGED; MOUTH; MOUTHWASHES; ORAL HYGIENE; PNEUMONIA, VENTILATOR-ASSOCIATED; RETROSPECTIVE STUDIES;

EID: 84857877504     PISSN: 00032417     EISSN: 1432055X     Source Type: Journal    
DOI: 10.1007/s00101-011-1954-4     Document Type: Article

References (30)

1. Alvarez-Lerma F, Maull E, Terradas R et al (2008) Moisturizing body milk as a reservoir of Burkholderia cepacia: outbreak of nosocomial infection in a multidisciplinary intensive care unit. Crit Care 12:R10
2. Baldwin A, Mahenthiralingam E, Drevinek P et al (2007) Environmental Burkholderia cepacia complex isolates in human infections. Emerg Infect Dis 13:458-461 (Pubitemid 46348134)
3. Balkhy HH, Cunningham G, Francis C et al (2005) A National Guard outbreak of Burkholderia cepacia infection and colonization secondary to intrinsic contamination of albuterol nebulization solution. Am J Infect Control 33:182-188 (Pubitemid 40417935)
4. Bosi C, Davin-Regli A, Charrel R et al (1996) Serratia marcescens nosocomial outbreak due to contamination of hexetidine solution. J Hosp Infect 33:217-224 (Pubitemid 26254423)
5. Bressler AM, Kaye KS, LiPuma JJ et al (2007) Risk factors for Burkholderia cepacia complex bacteremia among intensive care unit patients without cystic fibrosis: a case-control study. Infect Control Hosp Epidemiol 28:951-958 (Pubitemid 47218275)
6. Chan EY, Ruest A, Meade MO, Cook DJ (2007) Oral decontamination for prevention of pneumonia in mechanically ventilated adults: systematic review and meta-analysis. BMJ 334:889
7. Smet AM de, Kluytmans JA, Cooper BS et al (2009) Decontamination of the digestive tract and oropharynx in ICU patients. N Engl J Med 360:20-31
8. European Directorate for the Quality of Medicines & HealthCare (EDQM) (2008) European pharma- copoeia. http://www.edqm.eu/en/Background-Legal- Framework-50.html
9. Garrouste-Orgeas M, Chevret S, Arlet G et al (1997) Oropharyngeal or gastric colonization and nosocomial pneumonia in adult intensive care unit patients. A prospective study based on genomic DNA analysis. Am J Respir Crit Care Med 156:1647-1655 (Pubitemid 27505538)
10. Heo ST, Kim SJ, Jeong YG et al (2008) Hospital out-break of Burkholderia stabilis bacteraemia related to contaminated chlorhexidine in haematological malignancy patients with indwelling catheters. J Hosp Infect 70:241-245
11. Hutchins K, Karras G, Erwin J, Sullivan KL (2009) Ventilator-associated pneumonia and oral care: a successful quality improvement project. Am J Infect Control 37:590-597
12. Industrieverband Körperpflege und Waschmittel e. V. (1998) Leitfaden für Mikrobiologisches Qualitätsmanagement kosmetischer Mittel. http://www.ikw.org/pages/prodgr-details.php?info-id=187&navi-id= km&subnavi-id=koerperpflegemittel& s-key=MQM
13. Jimenez L, Smalls S (2000) Molecular detection of Burkholderia cepacia in toiletry, cosmetic, and pharmaceutical raw materials and finished products. J AOAC Int 83:963-966
14. Kohlenberg A, Schwab F, Geffers C et al (2008) Time- trends for Gram-negative and multidrug-resistant Gram-positive bacteria associated with nosocomial infections in German intensive care units between 2000 and 2005. Clin Microbiol Infect 14:93-96 (Pubitemid 350226579)
15. Kutty PK, Moody B, Gullion JS et al (2007) Multi-state outbreak of Burkholderia cenocepacia colonization and infection associated with the use of intrinsically contaminated alcohol-free mouth-wash. Chest 132:1825-1831
16. Liberati A, D'Amico R, Pifferi S et al (2009) Antibiotic prophylaxis to reduce respiratory tract infections and mortality in adults receiving intensive care. Cochrane Database Syst Rev:CD000022
17. Mahenthiralingam E, Baldwin A, Dowson CG (2008) Burkholderia cepacia complex bacteria: opportunistic pathogens with important natural biology. J Appl Microbiol 104:1539-1551 (Pubitemid 351724983)
18. Martin M, Christiansen B, Caspari G et al (2011) Hospital-wide outbreak of Burkholderia contaminans caused by prefabricated moist washcloths. J Hosp Infect 77:267-270
19. Memish ZA, Stephens G, Balkhy HH et al (2009) Outbreak of Burkholderia cepacia bacteremia in immunocompetent children caused by contaminated nebulized sulbutamol in Saudi Arabia. Am J Infect Control 37:431-432
20. Molina-Cabrillana J, Bolanos-Rivero M, Alvarez-Leon EE et al (2006) Intrinsically contaminated alcohol-free mouthwash implicated in a nosocomial outbreak of Burkholderia cepacia colonization and infection. Infect Control Hosp Epidemiol 27:1281-1282 (Pubitemid 44807481)
21. Rello J, Lode H, Cornaglia G, Masterton R (2010) A European care bundle for prevention of ventilator- associated pneumonia. Intensive Care Med 36:773-780
22. Romero-Gomez MP, Quiles-Melero MI, Pena Garcia P et al (2008) Outbreak of Burkholderia cepacia bacteremia caused by contaminated chlorhexi- dine in a hemodialysis unit. Infect Control Hosp Epidemiol 29:377-378 (Pubitemid 351416993)
23. Rose H, Baldwin A, Dowson CG, Mahenthiralingam E (2009) Biocide susceptibility of the Burkholderia cepacia complex. J Antimicrob Chemother 63:502-510
24. Rutala WA, Weber DJ, Thomann CA et al (1988) An outbreak of Pseudomonas cepacia bacteremia associated with a contaminated intra-aortic balloon pump. J Thorac Cardiovasc Surg 96:157-161
25. Schaffner W, Reisig G, Verrall RA (1973) Outbreak of Pseudomonas cepacia infection due to contaminated anaesthetics. Lancet 1:1050-1051
26. Segers P, Speekenbrink RG, Ubbink DT et al (2006) Prevention of nosocomial infection in cardiac surgery by decontamination of the nasopharynx and oropharynx with chlorhexidine gluconate: a randomized controlled trial. JAMA 296:2460-2466 (Pubitemid 44791202)
27. Sona CS, Zack JE, Schallom ME et al (2009) The impact of a simple, low-cost oral care protocol on ventilator-associated pneumonia rates in a surgical intensive care unit. J Intensive Care Med 24:54-62
28. Tablan OC, Anderson LJ, Besser R et al (2004) Guidelines for preventing health-care-associated pneumonia, 2003: recommendations of CDC and the Healthcare Infection Control Practices Advisory Committee. MMWR Recomm Rep 53:1-36
29. Tenover FC, Arbeit RD, Goering RV et al (1995) Interpreting chromosomal DNA restriction patterns produced by pulsed-field gel electrophoresis: criteria for bacterial strain typing. J Clin Microbiol 33:2233-2239
30. Yang CJ, Chen TC, Liao LF et al (2008) Nosocomial outbreak of two strains of Burkholderia cepacia caused by contaminated heparin. J Hosp Infect 69:398-400