Evaluation of the anti-inflammatory and antinociceptive properties of p-Cymene in mice

Zeitschrift fur Naturforschung - Section C Journal of Biosciences

Volumn 67, Issue 1-2, 2012, Pages 15-21

  Bonjardim, Leonardo R ^a   Cunha, Edisleide S ^a   Guimarães, Adriana G ^a   Santana, Michele F ^a   Oliveira, Makson G B ^a   Serafini, Mairim R ^a   Araújo, Adriano A S ^a   Antoniolli, Ângelo R ^a   Cavalcanti, Sócrates C H ^a   Santos, Marcio R V ^a   Quintans Júnior, Lucindo J ^a  

^a FEDERAL UNIVERSITY OF SERGIPE   (Brazil)

Author keywords

Inflammation; Monoterpene; P Cymene; Pain

Indexed keywords

MUS;

EID: 84857863990     PISSN: 09395075     EISSN: None     Source Type: Journal    
DOI: 10.1515/znc-2012-1-203     Document Type: Article

References (29)

1. Almeida R. N., Falcão A. C. G. M., Diniz R. S. T., Quintans-Júnior L. J., Polari R. M., Barbosa-Filho J. M., Agra M. F., Duarte J. C., Ferreira C. D., Antoniolli A. R., and Araújo C. C. (1999), Metodologia para avaliação de plantas com atividade no sistema nervoso central e alguns dados experimentais. Rev. Bras. Farm. 80, 72-76.
2. Almeida R. N., Navarro D. S., and Barbosa-Filho J. M. (2001), Plants with central analgesic activity. Phytomedicine 8, 310-322.
3. Arruda V. A., Ferreira de Araújo M., Bom C., and Lobo de Araújo A. (2003), Bothrops lanceolatus (Fer de Lance) venom stimulates leukocyte migration into the peritoneal cavity of mice. Toxicon 41, 99-107.
4. Bakkali F., Averbeck S., Averbeck D., and Idaomar M. (2008), Biological effects of essential oils-a review. Food Chem. Toxicol. 46, 446-475.
5. Bastos L. F., Merlo L. A., Rocha L. T., and Coelho M. M. (2007), Characterization of the antinociceptive and anti-inflammatory activities of doxycycline and minocycline in different experimental models. Eur. J. Pharmacol. 576, 171-179.
6. Broadbear J. H., Negus S. S., Butelman E. R., Costa B. R., and Woods J. H. (1994), Differential effects of systemically administered nor-binaltorphimine (nor- BNI) on k-opioid agonists in mouse writhing assay. Psychopharmacology 15, 311-319.
7. Dapino P., Ottonello L., and Dallegri F. (1994), The anti-inflammatory drug, nimesulide inhibits neutrophil adherence to an migration across monolayers of cytokine activated endothelial cells. Respirations 61, 336-341.
8. Dewick P. M. (2009), Medicinal Natural Products: a Biosynthetic Approach, 3rd ed. Wiley, Chichester, UK.
9. Dos Santos D. A., Fukui M. D. J., Dhammika Nanayakkara N. P., Khan S. I., Sousa J. P. B., Bastos J. K., Andrade S. F., Silva Filho A. A., and Quintao N. L. M. (2009), Anti-inflammatory and antinociceptive effects of Baccharis dracunculifolia DC (Asteraceae) in different experimental models. J. Ethnopharmacol. 127, 543-550.
10. Eddy N. B. and Leimbach D. (1953), Synthetic analgesics: IIR dithienyl-butenyl and dithienylbutylamines. J. Pharmacol. Exp. Ther. 107, 385-393.
11. Guimarães A. G., Oliveira G. F., Melo M. S., Cavalcanti S. C., Antoniolli A. R., Bonjardim L. R., Silva F. A., Santos J. P., Rocha R. F., Moreira J. C., Araújo A. A. S., Gelain D. P., and Quintans-Júnior L. J. (2010), Bioassay-guided valuation of antioxidant and antinociceptive activities of arvacrol. Basic Clin. Pharmacol. Toxicol. 107, 949-957.
12. Hotta M., Nakata R., Katsukawa M., Hori K., Takahashi S., and Inoue H. (2010), Carvacrol, a component of thyme oil, activates PPAR α and γ and suppresses COX-2 expression. J. Lipid Res. 51, 132-139.
13. Hunskaar S. and Hole K. (1987), The formalin test in mice: dissociation between inflammatory and noninflammatory pain. Pain 30, 103-104.
14. Khan H., Saeed M., Gilani A. H., Khan M. A., Dar A., and Khan I. (2010), The antinociceptive activity of Polygonatum verticillatum rhizomes in pain models. J. Ethnopharmacol. 127, 521-527.
15. Koster R., Anderson M., and Beer E. J. (1959), Acetic acid for analgesic screening. Federal Proc. 18, 412-416.
16. Le Bars D., Gozariu M., and Cadden S. W. (2001), Animal models of nociception. Pharmacol. Rev. 53, 597-652.
17. Loram L. C., Fuller A., Fick L. G., Cartmell T., Poole S., and Mitchell D. (2007), Cytokine profiles during carrageenan- induced inflammatory hyperalgesia in rat muscle and hind paw. J. Pain 8, 127-136.
18. Luengo M. A. M., Yates M., Domingo M. J. M., Casal B., Iglesias M., Esteban M., and Ruiz-Hitzky E. (2008), Synthesis of p-cymene from limonene, a renewable feedstock. Appl. Catal. B: Environ. 81, 218-224.
19. Melo M. S., Sena L. C. S., Barreto F. J. N., Bonjardim L. R., Almeida J. R. G. S., Lima J. T., De Sousa D. P., and Quintans-Júnior L. J. (2010), Antinociceptive effect of citronellal in mice. Pharm. Biol. 48, 411-416.
20. Philis J. G. (2005), The S1←S0 spectrum of jet-cooled p-cymene. Spectrochim. Acta Part A 61, 1239-1241.
21. Queiroz A. C., De Lira D. P., Dias T. L., De Souza E. T., Da Matta C. B., De Aquino A. B., Silva L. H., Da Silva D. J., Mella E. A., Agra M. F., Filho J. M., De Araújo-Júnior J. X., Santos B. V., and Alexandre-Moreira M. S. (2010), The antinociceptive and anti- inflammatory activities of Piptadenia stipulacea Benth. (Fabaceae). J. Ethnopharmacol. 128, 377-383.
22. Quintans-Júnior L. J., Melo M. S., De Sousa D. P., Araújo A. A. S., Onofre A. S. C., Gelain D. P., Goncalves J. C. R., Araújo D. A. M., Almeida J. R. G. S., and Bonjardim L. R. (2010), Antinociceptive activity of citronellal in formalin-, capsaicin-, and glutamate-induced orofacial nociception in rodents and its action on nerve excitability. J. Orofacial Pain 24, 305-312.
23. Quintans-Júnior L. J., Guimarães A. G., Santana M. T., Araújo B. E. S., Moreira F. V., Bonjardim L. R., Araújo A. A. S., Antoniolli A. R., Botelho M. A., Almeida J. R. G. S., and Santos M. R. V. (2011), Citral reduces nociceptive and inflammatory response in rodents. Braz. J. Pharmacogn. 21, 497-502.
24. Salvemini D., Wang Z. Q., Wyatt P. S., Bourdon D. M., Marino M. H., Manning P. T., and Currie M. G. (1996), Nitric oxide: a key mediator in the early and late phase of carrageenan-induced rat paw inflammation. Br. J. Pharmacol. 118, 829-838.
25. Santana M. F., Quintans-Júnior L. J., Cavalcanti S. C. H., Oliveira M. G. B., Guimarães A. G., Cunha E. S., Melo M. S., Santos M. R. V., Araújo A. A. S., and Bonjardim L. R. (2011), p-Cymene reduces orofacial nociceptive response in mice. Rev. Bras. Farmacogn. http://dx.doi.org/10.1590/S0102-695X2011005000156
26. Thomazzi S. M., Silva C. B., Silveira D. C., Vasconcellos C. L., Lira A. F., Cambui E. V., Estevam C. S., and Antoniolli A. R. (2010), Antinociceptive and antiinflammatory activities of Bowdichia virgilioides (sucupira). J. Ethnopharmacol. 127, 451-456.
27. Tjolsen A., Berge D. G., Hunskaar S., Rosland J. H., and Hole K. (1992), The formalin test: an evaluation of the method. Pain 51, 5-17.
28. Verma P. R., Joharapurkar A. A., Chatpalliwar V. A., and Asnani A. J. (2005), Antinociceptive activity of alcoholic extract of Hemidesmus indicus R. Br. in mice. J. Ethnopharmacol. 102, 298-301.
29. Walde A., Ve B., Scheline R. R., and Monge P. (1983), p-Cymene metabolism in rats and guinea-pigs. Xenobiotica 13, 503-512.