Can nebulized naloxone be used safely and effectively by emergency medical services for suspected opioid overdose?

Prehospital Emergency Care

Volumn 16, Issue 2, 2012, Pages 289-292

  Weber, Joseph M ^a   Tataris, Katie L ^a   Hoffman, Joyce D ^b   Aks, Steven E ^a   Mycyk, Mark B ^a  

^a Jr Hospital of Cook County   (United States)

^b Chicago Fire Department   (United States)

Author keywords

Naloxone; Nebulized; Opiate; Overdose; Prehospital

Indexed keywords

NALOXONE; NARCOTIC ANALGESIC AGENT; NARCOTIC ANTAGONIST;

ADOLESCENT; ADULT; AGED; ARTICLE; COHORT ANALYSIS; EMERGENCY HEALTH SERVICE; FEMALE; FOLLOW UP; HUMAN; INHALATIONAL DRUG ADMINISTRATION; INTOXICATION; MALE; METHODOLOGY; MIDDLE AGED; NEBULIZER; OPIATE ADDICTION; RETROSPECTIVE STUDY; RISK ASSESSMENT; SAFETY; TREATMENT OUTCOME;

ADMINISTRATION, INHALATION; ADOLESCENT; ADULT; AGED; ANALGESICS, OPIOID; COHORT STUDIES; EMERGENCY MEDICAL SERVICES; FEMALE; FOLLOW-UP STUDIES; HUMANS; MALE; MIDDLE AGED; NALOXONE; NARCOTIC ANTAGONISTS; NEBULIZERS AND VAPORIZERS; OPIOID-RELATED DISORDERS; OVERDOSE; RETROSPECTIVE STUDIES; RISK ASSESSMENT; SAFETY MANAGEMENT; TREATMENT OUTCOME; YOUNG ADULT;

EID: 84857846999     PISSN: 10903127     EISSN: 15450066     Source Type: Journal    
DOI: 10.3109/10903127.2011.640763     Document Type: Article

References (12)

1. Clarke SFJ, Dargan PI, Jones AL. Naloxone in opioid poisoning: walking a tightrope. Emerg Med J. 2005;22:612-6. (Pubitemid 41200623)
2. Barton ED, Ramos J, Colwell C, Benson J, Baily J, Dunn W. Intranasal administration of naloxone by paramedics. Prehosp Emerg Care. 2002;6:54-8. (Pubitemid 34041913)
3. Kelly AM, Koutsogiannis Z. Intranasal naloxone for life threatening opioid toxicity. [Letter] Emerg Med J. 2002;19:375. (Pubitemid 34830509)
4. Barton EB, Colwell CB, Wolfe T, et al. Efficacy of intranasal naloxone as a needleless alternative for treatment of opioid overdose in the prehospital setting. J Emerg Med. 2005;29:265-71. (Pubitemid 41383847)
5. Kelly AM, Kerr D, Dietze P, Patrick I, Walker T, Koutsogiannis Z. Randomised trial of intranasal versus intramuscular naloxone in prehospital treatment for suspected opioid overdose. Med J Austr. 2005;182:24-7. (Pubitemid 40089873)
6. Robertson TM, Hendey GW, Stroh G, Shalit M. Intranasal naloxone is a viable alternative to intravenous naloxone for prehospital narcotic overdose. Prehosp Emerg Care. 2009;13:512-5.
7. Merlin MA, Saybolt M, Kapitanyan R, et al. Intranasal naloxone delivery is an alternative to intravenous naloxone for opioid overdoses. Am J Emerg Med. 2010;28:296-303.
8. Mycyk MB, Szyszko AL, Aks SE. Nebulized naloxone gently and effectively reverses methadone intoxication. J Emerg Med. 2003;24:185-7. (Pubitemid 36269246)
9. Okie S. A flood of opioids, a rising tide of deaths. N Engl JMed. 2010;363:1981-3.
10. Leiss JK, Ratcliffe JM, Lyden JT, et al. Blood exposure among paramedics: incidence rates from the national study to prevent blood exposure in paramedics. Ann Epidemiol. 2006;16:720-5. (Pubitemid 44209374)
11. Wampler DA, Molina K, McManus J, Laws P, Manifold CA. No deaths associated with patient refusal of transport after naloxone-reversed opioid overdose. Prehosp Emerg Care. 2011;15:320-4.
12. Gilbert EH, Lowenstein SR, Koziol-McLain J, Barta DC, Steiner J. Chart reviews in emergency medicine research: where are the methods? Ann Emerg Med. 1996;27:305-8. (Pubitemid 26085005)