Intranasal naloxone is a viable alternative to intravenous naloxone for prehospital narcotic overdose

Prehospital Emergency Care

Volumn 13, Issue 4, 2009, Pages 512-515

  Robertson, Tania Mieke ^a   Hendey, Gregory W ^a   Stroh, Geoff ^a   Shalit, Marc ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Emergency medical services; Intranasal; Naloxone; Narcotic overdose

Indexed keywords

NALOXONE; NARCOTIC AGENT;

ADOLESCENT; ADULT; AGED; ARTICLE; BREATHING RATE; CHILD; CONTROLLED STUDY; DRUG ADMINISTRATION ROUTE; DRUG OVERDOSE; FEMALE; GLASGOW COMA SCALE; HUMAN; INTERMETHOD COMPARISON; MAJOR CLINICAL STUDY; MALE; NARCOTIC DEPENDENCE; PRESCHOOL CHILD; SCHOOL CHILD; TREATMENT RESPONSE;

ADMINISTRATION, INTRANASAL; ADOLESCENT; ADULT; AGED; CALIFORNIA; EMERGENCY MEDICAL SERVICES; FEMALE; HUMANS; INFUSIONS, INTRAVENOUS; MALE; MEDICAL RECORDS; MIDDLE AGED; NALOXONE; NARCOTIC ANTAGONISTS; OVERDOSE; RETROSPECTIVE STUDIES; YOUNG ADULT;

EID: 70149094183     PISSN: 10903127     EISSN: 15450066     Source Type: Journal    
DOI: 10.1080/10903120903144866     Document Type: Article

References (10)

1. Reisine T, Pasternak G. Opioid analgesics and antagonists. In: Hardman JG, Limbird LE, Molinoff PB, Ruddon RW, Gilman AG. Goodman and Gilman's Pharmacologic Basis of Therapeutics, 9th edition. Toronto, Ontario, Canada: McGraw-Hill, 1996, pp 549-551
2. Marx JA, Hockberger RS, Walls RM. Rosen's Emergency Medicine, 5th Edition. St. Louis, MO: Mosby, 2002, p 2184.
3. Popa V, Rients B. The effect of inhaled naloxone on resting bronchial tone and exercise-induced asthma. Am Rev Respir Dis. 1989;139:702-709
4. Wanger K, Brough L, Macmillan I, et al. Intravenous vs subcutaneous naloxone for out-of-hospital management of presumed opioid overdose. Acad Emerg Med. 1998;5:293-299
5. Barton ED, Ramos J, Colwell C, et al. Intranasal administration of naloxone by paramedics. Prehosp Emerg Care. 2002;6:54-58
6. Kelly AM, Koutsogiannis Z. Intranasal naloxone for life threatening opioid toxicity. Emerg Med J. 2002;19:375.
7. Kelley AM, Kerr D, Dietz P, et al. Randomized trial of intranasal versus intramuscular naloxone in prehospital treatment for suspected opioid overdose. MJA. 2005;182(1):24-27
8. Pontiroli AE, Calderara A, Pajetta E, et al. Intranasal glucagon for remedy of hypoglycemia. Studies in healthy subjects and type 1 diabetic patients. Diabetes Care. 1989;12:604-608
9. Hochreiter MC, Barton LL. Epidemiology of needlestick injury in emergency medical service personnel. J Emerg Med. 1988;6(1):9-12.
10. National Center for Infectious Diseases, Centers for Disease Control and Prevention. Exposure to blood: what healthcare personnel need to know. July 2003. Available at: http://www.cdc.gov/ncidod/dhqp/pdf/bbp/ExptoBlood.pdf. Accessed July 28, 2009.