Retrocyclin 2: A new therapy against avian influenza H5N1 virus in vivo and vitro

Biotechnology Letters

Volumn 32, Issue 3, 2010, Pages 387-392

  Liang, Qing long ^a,b   Zhou, Kai ^a,b   He, Hong xuan ^a  

^a INSTITUTE OF ZOOLOGY   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

Author keywords

Avian influenza virus; Chicken embryos; H5N1 virus; Influenza virus; MDCK cells; Retrocyclin 2

Indexed keywords

AVIAN INFLUENZA; CHICKEN EMBRYO; CHICKEN EMBRYOS; INFLUENZA VIRUS; MDCK CELLS;

MEATS; TRANSCRIPTION;

VIRUSES;

DEFENSIN;

ANIMAL; ARTICLE; AVIAN INFLUENZA; CELL LINE; CHICK EMBRYO; CHICKEN; DOG; GENE VECTOR; GENETICS; INFLUENZA VIRUS A H5N1; METABOLISM; PHYSIOLOGY; PLASMID; VIROLOGY; VIRUS REPLICATION;

ANIMALS; CELL LINE; CHICK EMBRYO; CHICKENS; DEFENSINS; DOGS; GENETIC VECTORS; INFLUENZA A VIRUS, H5N1 SUBTYPE; INFLUENZA IN BIRDS; PLASMIDS; VIRUS REPLICATION;

AVES; AVIAN INFLUENZA VIRUS; EUKARYOTA; ORTHOMYXOVIRIDAE;

EID: 77649336871     PISSN: 01415492     EISSN: 15736776     Source Type: Journal    
DOI: 10.1007/s10529-009-0167-2     Document Type: Article

References (14)

1. Barry DG, Daly NL, Clark RJ et al (2003) Linearization of a naturally occurring circular protein maintains structure but eliminates hemolytic activity. Biochemistry 42: 6688-6695.
2. Cole AM, Hong T, Boo LM et al (2002) Retrocyclin: a primate peptide that protects cells from infection by T- and M-tropic strains of HIV-1. Proc Natl Acad Sci USA 99: 1813-1818.
3. Craik DJ, Daly NL, Saska I et al (2003) Structures of naturally occurring circular proteins from bacteria. J Bacteriol 185: 4011-4021.
4. Doss M, White MR, Tecle T et al (2009) Interactions of α-, β-, and θ-defensins with Influenza A virus and surfactant protein D. J Immunol 182: 7878-7887.
5. Ge Q, McManus M, Nguyen T et al (2003) RNA interference of influenza virus production by directly targeting mRNA for degradation and indirectly inhibiting all viralRNA transcription. Proc Natl Acad Sci USA 100: 2718-2723.
6. Kim C, Gajendran N, Mittrucker H et al (2005) Human α-defensins neutralize anthrax lethal toxin and protect against its fatal consequences. Proc Natl Acad Sci USA 102: 4830-4835.
7. Munk C, Wei G, Yang OO et al (2003) The theta-defensin, retrocyclin, inhibits HIV-1 entry. AIDS Res Hum Retrovir 19: 875-881.
8. Nguyen TX, Cole AM, Lehrer RI (2003) Evolution of primate θ-defensins: a serpentine path to a sweet tooth. Peptides 24: 1647-1654.
9. Rosengren KJ, Daly NL, Plan MR et al (2003) Twists, knots, and rings in proteins. Structural definition of the cyclotide framework. J Biol Chem 278: 8606-8616.
10. Tang YQ, Yuan J, Osapay G et al (1999) A cyclic antimicrobial peptide produced in primate leukocytes by the ligation of two truncated alpha-defensins. Science 286: 498-502.
11. Trabi M, Schirra HJ, Craik DJ (2001) Three-dimensional structure of RTD-1, a cyclic antimicrobial defensin from rhesus macaque leukocytes. Biochemistry 40: 4211-4221.
12. Wang W, Cole AM, Hong T et al (2003) Retrocyclin, an antiretroviral theta-defensin, is a lectin. J Immunol 170: 4708-4716.
13. WHO (2009) Cumulative number of confirmed human cases of avian influenza A/(H5N1) reported to WHO. http://www. who. int/csr/disease/avian_influenza/country/cases_table_2009_06_02/en/index. html.
14. Yasin B, Wang W, Pang M et al (2004) θ Defensins protect cells from infection by herpes simplex virus by inhibiting viral adhesion and entry. J Virol 78: 5147-5156.