Stem cell therapy for arterial restenosis: Potential parameters contributing to the success of bone marrow-derived mesenchymal stromal cells

Cardiovascular Drugs and Therapy

Volumn 26, Issue 1, 2012, Pages 9-21

  Forte, Amalia ^a   Rinaldi, Barbara ^a   Sodano, Loredana ^a   Berrino, Liberato ^a   Rossi, Francesco ^a   Finicelli, Mauro ^b   Grossi, Mario ^a   Cobellis, Gilda ^a   Botti, Chiara ^a   De Feo, Marisa ^a   Santè, Pasquale ^a   Galderisi, Umberto ^a   Cipollaro, Marilena ^a  

^a SECOND UNIVERSITY OF NAPLES   (Italy)

^b Human Health Foundation   (Italy)

Author keywords

Inflammation; Mesenchymal stromal cells; Restenosis; Vascular endothelial growth factor

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; BROXURIDINE; CXCL1 CHEMOKINE; CYTOKINE; EPITHELIAL DERIVED NEUTROPHIL ACTIVATING FACTOR 78; GROWTH FACTOR; INTERCELLULAR ADHESION MOLECULE 1; L SELECTIN; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; VASCULOTROPIN;

AMINO ACID ANALYSIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTERIOTOMY; ARTICLE; BONE MARROW; CARDIOVASCULAR PARAMETERS; CAROTID ARTERY; CELL ACTIVITY; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; CYTOKINE RELEASE; DNA DAMAGE; IMMUNOMODULATION; IN VITRO STUDY; INFLAMMATION; MALE; MESENCHYMAL STROMA CELL; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN SECRETION; RAT; RESTENOSIS; STEM CELL TRANSPLANTATION; THERAPY EFFECT; TREATMENT OUTCOME;

ANIMALS; APOPTOSIS; BONE MARROW CELLS; CAROTID ARTERIES; CAROTID ARTERY INJURIES; CAROTID STENOSIS; CELL CYCLE; CELL DIFFERENTIATION; CELL PROLIFERATION; CELLS, CULTURED; CYTOKINES; DEOXYGUANOSINE; DNA DAMAGE; MALE; MESENCHYMAL STEM CELL TRANSPLANTATION; MESENCHYMAL STEM CELLS; RATS; RATS, WISTAR; RNA, MESSENGER; TOLL-LIKE RECEPTOR 2; TOLL-LIKE RECEPTOR 4; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84857791313     PISSN: 09203206     EISSN: 15737241     Source Type: Journal    
DOI: 10.1007/s10557-011-6359-8     Document Type: Article

References (43)

1. BK Lal 2007 Recurrent carotid stenosis after CEA and CAS: diagnosis and management Semin Vasc Surg 20 259 266 18082843 10.1053/j.semvascsurg.2007.10.009 (Pubitemid 350235867)
2. MF Pittenger AM Mackay SC Beck RK Jaiswal R Douglas JD Mosca, et al. 1999 Multilineage potential of adult human mesenchymal stem cells Science 284 143 147 10102814 10.1126/science.284.5411.143 1:CAS:528:DyaK1MXitlCnu7o%3D (Pubitemid 29282067)
3. KJ Beggs A Lyubimov JN Borneman A Bartholomew A Moseley R Dodds, et al. 2006 Immunologic consequences of multiple, high-dose administration of allogeneic mesenchymal stem cells to baboons Cell Transplant. 15 711 721 17269442 10.3727/000000006783981503 (Pubitemid 46095254)
4. M Yokokawa S Ohnishi H Ishibashi-Ueda H Obata K Otani Y Miyahara, et al. 2008 Transplantation of mesenchymal stem cells improves atrioventricular conduction in a rat model of complete atrioventricular block Cell Transplant. 17 1145 1155 19181209 10.3727/096368908787236594
5. A Shabbir D Zisa H Lin M Mastri G Roloff G Suzuki, et al. 2010 Activation of host tissue trophic factors through JAK-STAT3 signaling: a mechanism of mesenchymal stem cell-mediated cardiac repair Am J Physiol Heart Circ Physiol 299 H1428 H1438 20852053 10.1152/ajpheart.00488.2010 1:CAS:528: DC%2BC3cXhsFSkt7nL
6. AI Caplan JE Dennis 2006 Mesenchymal stem cells as trophic mediators J Cell Biochem 98 1076 1084 16619257 10.1002/jcb.20886 1:CAS:528: DC%2BD28XnsVyjtL0%3D (Pubitemid 44128350)
7. A Forte G Di Micco U Galderisi FM Guarino M Cipollaro M De Feo, et al. 2001 Molecular analysis of arterial stenosis in rat carotids J Cell Physiol 186 307 313 11169467 10.1002/1097-4652(200002)186:2<307::AID-JCP1029>3.0.CO;2- I 1:CAS:528:DC%2BD3MXktVKkuw%3D%3D (Pubitemid 32041889)
8. A Forte M Finicelli M Mattia L Berrino F Rossi M De Feo, et al. 2008 Mesenchymal stem cells effectively reduce surgically induced stenosis in rat carotids J Cell Physiol 217 789 799 18690654 10.1002/jcp.21559 1:CAS:528:DC%2BD1cXhtlOqt7vM
9. Forte A, Finicelli M, Grossi M, Vicchio M, Alessio N, Sante P, et al. DNA damage and repair in a model of rat vascular injury. Clin Sci (Lond). 2009. doi: 10.1042/SC20090416.
10. M Dominici K Le Blanc I Mueller I Slaper-Cortenbach F Marini D Krause, et al. 2006 Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement Cytotherapy 8 315 317 16923606 10.1080/14653240600855905 1:STN:280:DC%2BD28vpvFSjsA%3D%3D (Pubitemid 44269669)
11. WL Neeley JM Essigmann 2006 Mechanisms of formation, genotoxicity, and mutation of guanine oxidation products Chem Res Toxicol 19 491 505 16608160 10.1021/tx0600043 1:CAS:528:DC%2BD28Xis1Omt70%3D
12. A Forte M Finicelli P De Luca C Quarto F Onorati P Sante, et al. 2008 Expression profiles in surgically-induced carotid stenosis: a combined transcriptomic and proteomic investigation J Cell Mol Med. 12 1956 1973 19012726 10.1111/j.1582-4934.2008.00212.x 1:CAS:528:DC%2BD1cXhsVOgu73J
13. D Li C Zhang F Song I Lubenec Y Tian QH Song 2009 VEGF regulates FGF-2 and TGF-beta1 expression in injury endothelial cells and mediates smooth muscle cells proliferation and migration Microvasc Res 77 134 142 18948122 10.1016/j.mvr.2008.09.007 1:CAS:528:DC%2BD1MXisFWgu7s%3D
14. SC Hollestelle MR De Vries JK Van Keulen AH Schoneveld A Vink CF Strijder, et al. 2004 Toll-like receptor 4 is involved in outward arterial remodeling Circulation 109 393 398 14699006 10.1161/01.CIR.0000109140.51366.72 1:CAS:528:DC%2BD2cXks1Cjug%3D%3D (Pubitemid 38139309)
15. AI Caplan 2009 Why are MSCs therapeutic? New data: new insight J Pathol 217 318 324 19023885 10.1002/path.2469 1:STN:280:DC%2BD1M%2FgsVChtA%3D%3D
16. L Chen EE Tredget PY Wu Y Wu 2008 Paracrine factors of mesenchymal stem cells recruit macrophages and endothelial lineage cells and enhance wound healing PLoS One 3 e1886 18382669 10.1371/journal.pone.0001886 (Pubitemid 351943822)
17. Salvolini E, Orciani M, Vignini A, Mattioli-Belmonte M, Mazzanti L, Di Primio R. Skin-derived mesenchymal stem cells (S-MSCs) induce endothelial cell activation by paracrine mechanisms. Exp Dermatol. 19:848-50.
18. Novo E, Busletta C, Bonzo LV, Povero D, Paternostro C, Mareschi K, et al. Intracellular reactive oxygen species are required for directional migration of resident and bone marrow-derived hepatic pro-fibrogenic cells. J Hepatol. 54:964-74.
19. Song H, Cha MJ, Song BW, Kim IK, Chang W, Lim S, et al. Reactive oxygen species inhibit adhesion of mesenchymal stem cells implanted into ischemic myocardium via interference of focal adhesion complex. Stem Cells. 28:555-63.
20. C Lanza S Morando A Voci L Canesi MC Principato LD Serpero, et al. 2009 Neuroprotective mesenchymal stem cells are endowed with a potent antioxidant effect in vivo J Neurochem 110 1674 1684 19619133 10.1111/j.1471-4159.2009. 06268.x 1:CAS:528:DC%2BD1MXhtVyntbrK
21. Witherick J, Wilkins A, Scolding N, Kemp K. Mechanisms of oxidative damage in multiple sclerosis and a cell therapy approach to treatment. Autoimmune Dis. 2011:164608.
22. Tsubokawa T, Yagi K, Nakanishi C, Zuka M, Nohara A, Ino H, et al. Impact of anti-apoptotic and anti-oxidative effects of bone marrow mesenchymal stem cells with transient overexpression of heme oxygenase-1 on myocardial ischemia. Am J Physiol Heart Circ Physiol. 298:H1320-9.
23. S Schrepfer T Deuse H Reichenspurner MP Fischbein RC Robbins MP Pelletier 2007 Stem cell transplantation: the lung barrier Transplant Proc 39 573 576 17362785 10.1016/j.transproceed.2006.12.019 1:CAS:528:DC%2BD2sXjtFGnsLk%3D (Pubitemid 46386222)
24. PJ Psaltis AC Zannettino SG Worthley S Gronthos 2008 Concise review: mesenchymal stromal cells: potential for cardiovascular repair Stem Cells. 26 2201 2210 18599808 10.1634/stemcells.2008-0428
25. Lange C, Brunswig-Spickenheier B, Cappallo-Obermann H, Eggert K, Gehling UM, Rudolph C, et al. Radiation rescue: mesenchymal stromal cells protect from lethal irradiation. PLoS One. 6:e14486.
26. S Sadat S Gehmert YH Song Y Yen X Bai S Gaiser, et al. 2007 The cardioprotective effect of mesenchymal stem cells is mediated by IGF-I and VEGF Biochem Biophys Res Commun 363 674 679 17904522 10.1016/j.bbrc.2007.09.058 1:CAS:528:DC%2BD2sXhtFCjtrzE (Pubitemid 47513683)
27. R Hutter FE Carrick C Valdiviezo C Wolinsky JS Rudge SJ Wiegand, et al. 2004 Vascular endothelial growth factor regulates reendothelialization and neointima formation in a mouse model of arterial injury Circulation 110 2430 2435 15477421 10.1161/01.CIR.0000145120.37891.8A 1:CAS:528:DC%2BD2cXosVSlsL0%3D (Pubitemid 39407350)
28. T Asahara C Bauters C Pastore M Kearney S Rossow S Bunting, et al. 1995 Local delivery of vascular endothelial growth factor accelerates reendothelialization and attenuates intimal hyperplasia in balloon-injured rat carotid artery Circulation 91 2793 2801 7758186 1:CAS:528:DyaK2MXms1Sisr8%3D
29. TA Markel Y Wang JL Herrmann PR Crisostomo M Wang NM Novotny, et al. 2008 VEGF is critical for stem cell-mediated cardioprotection and a crucial paracrine factor for defining the age threshold in adult and neonatal stem cell function Am J Physiol Heart Circ Physiol 295 H2308 H2314 18849336 10.1152/ajpheart.00565.2008 1:CAS:528:DC%2BD1cXhsFSntb3F
30. G Cobellis C Maione C Botti A Coppola A Silvestroni S Lillo, et al. 2010 Beneficial effects of VEGF secreted from stromal cells in supporting endothelial cell functions: therapeutic implications for critical limb ischemia Cell Transplant. 19 1425 1437 20587143 10.3727/096368910X509068
31. B Bakondi IS Shimada BM Peterson JL Spees 2011 SDF-1alpha secreted by human CD133-derived multipotent stromal cells promotes neural progenitor cell survival through CXCR7 Stem Cells Dev. 20 1021 1029 20854168 10.1089/scd.2010.0198 1:CAS:528:DC%2BC3MXmslaju7s%3D
32. F Wang T Yasuhara T Shingo M Kameda N Tajiri WJ Yuan, et al. 2010 Intravenous administration of mesenchymal stem cells exerts therapeutic effects on parkinsonian model of rats: focusing on neuroprotective effects of stromal cell-derived factor-1alpha BMC Neurosci 11 52 20420688 10.1186/1471-2202-11-52 1:CAS:528:DC%2BC3cXmtlaitrk%3D
33. T Schinkothe W Bloch A Schmidt 2008 In vitro secreting profile of human mesenchymal stem cells Stem Cells Dev. 17 199 206 18208373 10.1089/scd.2007.0175 1:CAS:528:DC%2BD1cXhvVyks74%3D (Pubitemid 351271619)
34. Y Yin X Zhao Y Fang S Yu J Zhao M Song, et al. 2010 SDF-1alpha involved in mobilization and recruitment of endothelial progenitor cells after arterial injury in mice Cardiovasc Pathol 19 218 227 19502087 10.1016/j.carpath.2009.04. 002 1:CAS:528:DC%2BC3cXos1Cjsr4%3D
35. JM Li X Zhang PR Nelson PR Odgren JD Nelson C Vasiliu, et al. 2007 Temporal evolution of gene expression in rat carotid artery following balloon angioplasty J Cell Biochem 101 399 410 17171642 10.1002/jcb.21190 1:CAS:528:DC%2BD2sXltFCrtbY%3D (Pubitemid 46698874)
36. ZR Deng C Yang AQ Ma XY Chen T Geng 2006 Dynamic changes of plasma VEGF, SDF-1 and peripheral CD34+ cells in patients with acute myocardial infarction Nan Fang Yi Ke Da Xue Xue Bao. 26 1637 1640 17121721 1:CAS:528: DC%2BD28XhtlCku7%2FO
37. SC Pitchford RC Furze CP Jones AM Wengner SM Rankin 2009 Differential mobilization of subsets of progenitor cells from the bone marrow Cell Stem Cell. 4 62 72 19128793 10.1016/j.stem.2008.10.017 1:CAS:528:DC%2BD1MXhtVSks70%3D
38. R Chirco XW Liu KK Jung HR Kim 2006 Novel functions of TIMPs in cell signaling Cancer Metastasis Rev 25 99 113 16680576 10.1007/s10555-006-7893-x 1:CAS:528:DC%2BD28Xktlaksro%3D (Pubitemid 43723986)
39. ME Taube XW Liu R Fridman HR Kim 2006 TIMP-1 regulation of cell cycle in human breast epithelial cells via stabilization of p27(KIP1) protein Oncogene 25 3041 3048 16407831 10.1038/sj.onc.1209336 1:CAS:528:DC%2BD28Xks1Orsb8%3D (Pubitemid 43780468)
40. Y Huo C Weber SB Forlow M Sperandio J Thatte M Mack, et al. 2001 The chemokine KC, but not monocyte chemoattractant protein-1, triggers monocyte arrest on early atherosclerotic endothelium J Clin Invest 108 1307 1314 11696575 1:CAS:528:DC%2BD3MXot12kt70%3D (Pubitemid 33107758)
41. ML Choong YP Yong AC Tan B Luo HF Lodish 2004 LIX: a chemokine with a role in hematopoietic stem cells maintenance Cytokine 25 239 245 15036238 10.1016/j.cyto.2003.11.002 1:CAS:528:DC%2BD2cXhsV2hu70%3D (Pubitemid 38229893)
42. Zarbock A, Ley K, McEver RP, Hidalgo A. Leukocyte ligands for endothelial selectins: specialized glycoconjugates that mediate rolling and signaling under flow. Blood. 2011;
43. R Halwani J Al-Abri M Beland H Al-Jahdali AJ Halayko TH Lee, et al. 2011 CC and CXC chemokines induce airway smooth muscle proliferation and survival J Immunol 186 4156 4163 21368236 10.4049/jimmunol.1001210 1:CAS:528: DC%2BC3MXjvVKmurw%3D