Microfluidics: Analog-to-digital drug screening

Nature

Volumn 483, Issue 7387, 2012, Pages 43-44

  Wootton, Robert C R ^a   Demello, Andrew J ^a  

^a ETH ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL COMPOUND; ENZYME INHIBITOR;

BIOACTIVITY; BIOASSAY; CONCENTRATION (COMPOSITION); DOSE-RESPONSE RELATIONSHIP; DRUG; ENZYME ACTIVITY; INHIBITOR; QUALITATIVE ANALYSIS; RADICAL;

ACCURACY; ANALOG COMPUTER; ANALYTIC METHOD; BIOLOGICAL ACTIVITY; CONTINUOUS FLOW REACTOR; DENSITY GRADIENT; DIGITAL COMPUTER; DISPERSION; DRUG SCREENING; ENZYME ACTIVITY; INTERMETHOD COMPARISON; MICROFLUIDICS; MOLECULAR LIBRARY; PRIORITY JOURNAL; SHORT SURVEY;

ANALOG-DIGITAL CONVERSION; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG EVALUATION, PRECLINICAL; ENZYME INHIBITORS; HIGH-THROUGHPUT SCREENING ASSAYS; MICROFLUIDICS;

EID: 84857776037     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/483043a     Document Type: Short Survey

References (5)

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3. Inglese, J. et al. Proc. Natl Acad. Sci. USA 103, 11473-11478 (2006).
4. Hong, J., Edel, J. B. & deMello, A. J. Drug Discov. Today 14, 134-146 (2009).
5. Niu, X., Gielen, F., Edel, J. B. & deMello, A. J. Nature Chem. 3, 437-442 (2011).