Flavonoid glycosides isolated from unique legume plant extracts as novel inhibitors of xanthine oxidase

PLoS ONE

Volumn 7, Issue 3, 2012, Pages

  Spanou, Chrysoula ^a   Veskoukis, Aristidis S ^a   Kerasioti, Thalia ^a   Kontou, Maria ^a   Angelis, Apostolos ^b   Aligiannis, Nektarios ^b   Skaltsounis, Alexios Leandros ^b   Kouretas, Dimitrios ^a  

^a UNIVERSITY OF THESSALY   (Greece)

^b UNIVERSITY OF ATHENS   (Greece)

Author keywords

[No Author keywords available]

Indexed keywords

ALLOPURINOL; FLAVONOID GLYCOSIDE; KAEMPFEROL 3 O (2 O ACETYL ALPHA LEVO RHAMNOPYRANOSYL) 7 O ALPHA LEVO RHAMNOPYRANOSIDE; KAEMPFEROL 3 O (3 O ACETYL ALPHA LEVO RHAMNOPYRANOSYL) 7 O ALPHA LEVO RHAMNOPYRANOSIDE; KAEMPFEROL 3 O (5 O ACETYL BETA DEXTRO APIOFURANOSYL) 7 O ALPHA LEVO RHAMNOPYRANOSIDE; KAEMPFEROL 3 O (6 O BETA DEXTRO ACETYLGLUCOPYRANOSYL) 7 O ALPHA LEVO RHAMNOPYRANOSIDE; KAEMPFEROL 3 O [ALPHA LEVO RHAMNOPYRANOSYL(1-2) BETA DEXTRO GALACTOPYRANOSYL] 7 O ALPHA LEVO RHAMNOPYRANOSIDE; KAEMPFEROL 3 O [ALPHA LEVO RHAMNOPYRANOSYL(1-2) BETA DEXTRO GLUCOPYRANOSYL] 7 O ALPHA LEVO RHAMNOPYRANOSIDE; KAEMPFEROL 3 O ALPHA LEVO ARABINOPYRANOSYL 7 O ALPHA LEVO RHAMNOPYRANOSIDE; KAEMPFEROL 3 O ALPHA LEVO RHAMNOPYRANOSYL 7 O ALPHA LEVO RHAMNOPYRANOSIDE; KAEMPFEROL 3 O BETA DEXTRO APIOFURANOSYL 7 O ALPHA LEVO RHAMNOPYRANOSIDE; KAEMPFEROL 3 O BETA DEXTRO GALACTOPYRANOSYL 7 O ALPHA LEVO RHAMNOPYRANOSIDE; KAEMPFEROL 3 O BETA DEXTRO GLUCOPYRANOSYL 7 O ALPHA LEVO RHAMNOPYRANOSIDE; LOTUS EDULIS EXTRACT; PLANT EXTRACT; QUERCETIN 3 O [ALPHA LEVO RHAMNOPYRANOSYL(1-2) 6 O ACETYL BETA DEXTRO GALACTOPYRANOSYL] 7 O ALPHA LEVO RHAMNOPYRANOSIDE; QUERCETIN 3 O [ALPHA LEVO RHAMNOPYRANOSYL(1-2) BETA DEXTRO GALACTOPYRANOSYL] 7 O ALPHA LEVO RHAMNOPYRANOSIDE; QUERCETIN 3 O [ALPHA LEVO RHAMNOPYRANOSYL(1-2) BETA DEXTRO GLUCOPYRANOSYL] 7 O ALPHA LEVO RHAMNOPYRANOSIDE; ROSEOSIDE; UNCLASSIFIED DRUG; XANTHINE OXIDASE INHIBITOR; ANTIOXIDANT; ENZYME INHIBITOR; FLAVONOID; GLYCOSIDE; POLYPHENOL; XANTHINE OXIDASE;

ARTICLE; COMPETITIVE INHIBITION; CONTROLLED STUDY; DRUG DETERMINATION; DRUG ISOLATION; DRUG MECHANISM; DRUG POTENCY; DRUG STRUCTURE; ENZYME INHIBITION; IC 50; LEGUME; LOTUS EDULIS; NONCOMPETITIVE INHIBITION; NONHUMAN; STRUCTURE ACTIVITY RELATION; VICIA FABA; ANIMAL; CATTLE; CHEMICAL MODEL; CHEMISTRY; DIET SUPPLEMENTATION; DRUG ANTAGONISM; DRUG DESIGN; FABACEAE; HUMAN; KINETICS; LOTUS; METABOLISM; METHODOLOGY; PLANT LEAF; STATISTICAL MODEL;

LOTUS EDULIS; VICIA FABA;

ANIMALS; ANTIOXIDANTS; CATTLE; CHEMISTRY, PHARMACEUTICAL; DIETARY SUPPLEMENTS; DRUG DESIGN; ENZYME INHIBITORS; FABACEAE; FLAVONOIDS; GLYCOSIDES; HUMANS; INHIBITORY CONCENTRATION 50; KINETICS; LOTUS; MODELS, CHEMICAL; MODELS, STATISTICAL; PLANT EXTRACTS; PLANT LEAVES; POLYPHENOLS; VICIA FABA; XANTHINE OXIDASE;

EID: 84857763136     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0032214     Document Type: Article

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