Assessment of interindividual variability of plasma concentrations after administration of high doses of intravenous amoxicillin or cloxacillin in critically ill patients

Journal of Chemotherapy

Volumn 23, Issue 5, 2011, Pages 277-281

  Verdier, M C ^a   Tribut, O ^a   Tattevin, P ^a   Michelet, C ^a   Bentue Ferrer D ^a  

^a PONTCHAILLOU UNIVERSITY HOSPITAL   (France)

Author keywords

Amoxicillin; Cloxacillin; Intravenous administration; Pharmacokinetic variability; Therapeutic drug monitoring

Indexed keywords

AMOXICILLIN; CLOXACILLIN; CREATININE; ANTIINFECTIVE AGENT;

ADULT; AGED; ARTICLE; BACTERIAL ENDOCARDITIS; COMMUNITY ACQUIRED INFECTION; CONTINUOUS INFUSION; CREATININE BLOOD LEVEL; CREATININE CLEARANCE; CRITICALLY ILL PATIENT; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG INTERMITTENT THERAPY; DRUG MEGADOSE; DRUG TREATMENT FAILURE; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; INFECTION; KIDNEY DISEASE; KIDNEY FUNCTION; MAJOR CLINICAL STUDY; MALE; METHICILLIN SUSCEPTIBLE STAPHYLOCOCCUS AUREUS; MINIMUM INHIBITORY CONCENTRATION; OBSERVATIONAL STUDY; PATIENT ASSESSMENT; PHARMACOKINETICS; RETROSPECTIVE STUDY; BACTERIAL INFECTION; BLOOD; DRUG ADMINISTRATION; HOSPITALIZATION; INTENSIVE CARE UNIT; INTRAVENOUS DRUG ADMINISTRATION; ISOLATION AND PURIFICATION; KIDNEY FAILURE; MEDICAL RECORD; METABOLISM; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MICROBIOLOGY; MIDDLE AGED; PATHOPHYSIOLOGY; REPRODUCIBILITY; STREPTOCOCCUS INFECTION;

ADULT; AGED; AGED, 80 AND OVER; AMOXICILLIN; ANTI-BACTERIAL AGENTS; BACTERIAL INFECTIONS; CLOXACILLIN; CREATININE; DRUG ADMINISTRATION SCHEDULE; ENDOCARDITIS, BACTERIAL; FEMALE; HUMANS; INFUSIONS, INTRAVENOUS; INTENSIVE CARE UNITS; MALE; MEDICAL RECORDS; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; MIDDLE AGED; RENAL INSUFFICIENCY; REPRODUCIBILITY OF RESULTS; RETROSPECTIVE STUDIES; SEVERITY OF ILLNESS INDEX; STREPTOCOCCAL INFECTIONS;

EID: 84857721004     PISSN: 1120009X     EISSN: 19739478     Source Type: Journal    
DOI: 10.1179/joc.2011.23.5.277     Document Type: Article

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