Thiamine (vitamin B 1)

Complementary Health Practice Review

Volumn 16, Issue 1, 2011, Pages 12-20

  Fattal Valevski, Aviva ^a  

^a TEL AVIV SOURASKY MEDICAL CENTER   (Israel)

Author keywords

beriberi; cardiomyopathy; neuropathy; thiamine; vitamin B 1; Wernicke Korsakoff syndrome

Indexed keywords

EID: 84857714997     PISSN: 15332101     EISSN: 15523845     Source Type: Journal    
DOI: 10.1177/1533210110392941     Document Type: Review

References (98)

1. Bontius J. De paralyseos quadam specie quam indigenae beriberi vocant. In: De Medicina Indorum 1645 lib. 3, cap I. Lugdum, Batavia.
2. The bacillus of beriberi. Science. 1884;3:331-332.
3. Beri-beri and anchylostomiasis. BMJ. 1892;2:28-29.
4. Ashmead AS Three ships with beriberi outbreaks shown to have had extensive formation of carbonic oxides during the voyage-analysis of beriberi blood. Conclusion that beriberi is nothing but carbonic poisoning of the blood. Science. 1893;22:48-49.
5. Macleod N. Can beri-beri be caused by food supplies from countries where beri-beri is endemic? BMJ. 1897;2:390-392.
6. Ross R., Reynolds ES A case of beri-beri (?) possibly due to arsenic poisoning. Br Med J. 1901;2:979-980.
7. Rosenfeld L. Vitamine-vitamin. The early years of discovery. Clin Chem. 1997;43:4:680-685.
8. Funk C. On the chemical nature of the substance which cures polyneuritis in birds induced by a diet of polished rice. J Physiol. 1911;43:395-400.
9. Funk C. The etiology of the deficiency diseases. Beri-beri, polyneuritis in birds, epidemic dropsy, scurvy, experimental scurvy in animals, infantile scurvy, ship beri-beri, pellagra. J State Med (London). 1912;20:341-368.
10. Jansen BCP, Donath WF On the isolation of antiberiberi vitamin. Proc Kon Ned Akad Wet. 1926;29:1390.
11. 1. J Am Chem Soc. 1936;58:1504-1505.
12. Williams RR The chemistry and biological significance of thiamin. Science. 1938;87:559-563.
13. 1. By Joseph K. Cline, Robert R. Williams, and Jacob Finkeltstein. Nutr Rev. 1977;35:238-240.
14. Dewardener HE, Lennox B. Cerebral beriberi (Wernicke's encephalopathy): review of 52 cases in a Singapore prisoner-of-war hospital. Lancet. 1947;4:11-17.
15. Thomson AD, Cook CC, Guerrini I., Sheedy D., Harper C., Marshall EJ Wernicke's encephalopathy revisited. Translation of the case history section of the original manuscript by Carl Wernicke "Lehrbuch der Gehirnkrankheiten fur Aerzte and Studirende" (1881) with a commentary. Alcohol Alcohol. 2008;43:174-179.
16. World Health Organization. Thiamine Deficiency and Its Prevention and Control in Major Emergencies. Geneva, Switzerland: Department of Nutrition for Health and Development, World Health Organization; 1999.
17. Butterworth RF, Kril JJ, Harper CG Thiamine-dependent enzyme changes in the brains of alcoholics: relationship to the Wernicke-Korsakoff syndrome. Alcohol Clin Exp Res. 1993; 17:1084-1088.
18. Bubber P., Ke ZJ, Gibson GE Tricarboxylic acid cycle enzymes following thiamine deficiency. Neurochem Int. 2004;45: 1021-1028.
19. Blass JP, Gibson GE Abnormality of a thiamine-requiring enzyme in patients with Wernicke-Korsakoff syndrome. New Engl J Med. 1977;297:1367-1370.
20. Pekovich SR, Martin PR, Singleton CK Thiamine deficiency decreases steady-state transketolase and pyruvate dehydrogenase but not alpha-ketoglutarate dehydrogenase mRNA levels in three human cell types. J Nutr. 1998;128:683-687.
21. Gibson GE, Ksiezak-Reding H., Sheu KF, Mykytyn V., Blass JP Correlation of enzymatic, metabolic, and behavioral deficits in thiamin deficiency and its reversal. Neurochem Res. 1984;9: 803-814.
22. Aikawa H., Watanabe IS, Furuse T.,et al.Low energy levels in thiamine-deficient encephalopathy. J Neuropathol Exp Neurol. 1984;43:276-287.
23. Holowach J., Kauffman F., Ikossi MG, Thomas C., McDougal DB Jr. The effects of a thiamine antagonist, pyrithiamine, on levels of selected metabolic intermediates and on activities of thiamine-dependent enzymes in brain and liver. J Neurochem. 1968;15: 621-631.
24. McCandless DW, Schenker S., Cook M. Encephalopathy of thiamine deficiency: studies of intracerebral mechanisms. J Clin Invest. 1968;47:2268-2280.
25. Hakim AM The induction and reversibility of cerebral acidosis in thiamine deficiency. Ann Neurol. 1984;16:673-679.
26. Bettendorff L. Thiamine homeostasis in neuroblastoma cells. Neurochem Int. 1995;26:295-302.
27. Pannunzio P., Hazell AS, Pannunzio M., Rao KV, Butterworth RF Thiamine deficiency results in metabolic acidosis and energy failure in cerebellar granule cells: an in vitro model for the study of cell death mechanisms in Wernicke's encephalopathy. J Neurosci Res. 2000;62:286-292.
28. Zhang SX, Weilersbacher GS, Henderson SW, Corso T., Olney JW, Langlais PJ Excitotoxic cytopathology, progression, and reversibility of thiamine deficiency-induced diencephalic lesions. J Neuropathol Exp Neurol. 1995;54:255-267.
29. Wang JJ, Hua Z., Fentress HM, Singleton CK JNK1 is inactivated during thiamine deficiency-induced apoptosis in human neuroblastoma cells. J Nutr Biochem. 2000;11:208-215.
30. Heinrich CP, Stadler H., Weiser H. The effect of thiamine deficiency on the acetylcoenzyme A and acetylcholine levels in the rat brain. J Neurochem. 1973;21:1273-1281.
31. Jankowska-Kulawy A., Bielarczyk H., Pawéczyk T., Wróblewska M., Szutowicz A. Acetyl-CoA and acetylcholine metabolism in nerve terminal compartment of thiamine deficient rat brain. J Neurochem. 2010;115:333-342.
32. Gaitonde MK, Fayein NA, Johnson AL Decreased metabolism in vivo of glucose into amino acids of the brain of thiamine-deficient rats after treatment with pyrithiamine. J Neurochem. 1975;24: 1215-1223.
33. Hazell AS, Butterworth RF, Hakim AM Cerebral vulnerability is associated with selective increase in extracellular glutamate concentration in experimental thiamine deficiency. J Neurochem. 1993;61:1155-1158.
34. Héroux M., Butterworth RF Reversible alterations of cerebral gamma-aminobutyric acid in pyrithiamine-treated rats: implications for the pathogenesis of Wernicke's encephalopathy. J Neurochem. 1988;51:1221-1226.
35. Langlais PJ, Zhang SX Extracellular glutamate is increased in thalamus during thiamine deficiency-induced lesions and is blocked by MK-801. J Neurochem. 1993;61:2175-2182.
36. Todd KG, Butterworth RF Evaluation of the role of NMDAmediated excitotoxicity in the selective neuronal loss in experimental Wernicke encephalopathy. Exp Neurol. 1998; 149:130-138.
37. Slekar KH, Kosman DJ, Culotta VC The yeast copper/zinc super-oxide dismutase and the pentose phosphate pathway play overlapping roles in oxidative stress protection. J Biol Chem. 1996;271: 28831-28836.
38. Calingasan NY, Chun WJ, Park LC, Uchida K., Gibson GE Oxidative stress is associated with region-specific neuronal death during thiamine deficiency. J Neuropathol Exp Neurol. 1999; 58:946-958.
39. Boros LG, Steinkamp MP, Fleming JC, Lee WN, Cascante M., Neufeld EJ Defective RNA ribose synthesis in fibroblasts from patients with thiamine-responsive megaloblastic anemia (TRMA). Blood. 2003;102:3556-3561.
40. Blair PV, Kobayashi R., Edwards HM 3rd, Shay NF, Baker DH, Harris RA Dietary thiamin level influences levels of its diphosphate form and thiamin-dependent enzymic activities of rat liver. J Nutr.1999;129:641-648.
41. Zieve L., Doizaki WM, Stenroos LE Effect of magnesium deficiency on blood and liver transketolase activity and on the recovery of enzyme activity in thiamine-deficient rats receiving thiamine. J Lab Clin Med. 1968;72:268-277.
42. Morgan MY Alcohol and nutrition. Br Med Bull. 1982;38:21-29.
43. Traviesa DC Magnesium deficiency: a possible cause of thiamine refractoriness in Wernicke-Korsakoff encephalopathy. J Neurol Neurosurg Psychiatry. 1974;37:959-962.
44. Mclean J., Manchip S. Wernicke's encephalopathy induced by magnesium depletion. Lancet. 1999;353:1768.
45. Rao J., Oz G., Seaquist ER Regulation of cerebral glucose metabolism. Minerva Endocrinol. 2006;31:149-158.
46. Siebert G., Gessner B., Klasser M. Energy supply of the central nervous system. In: Somogyi JC, Hotzel D, eds. Nutrition and Neurobiology. Basel, Switzerland: Karger; 1986:1-26.
47. Ishii K., Sarai K., Sanemori H., Kawasaki T. Concentration of thiamine and its phosphate esters in rat tissues determined by high pressure liquid chromatography. J Nutr Sci Vitaminol (Tokyo). 1979;25:517-523.
48. Bâ A. Metabolic and structural role of thiamine in nervous tissues. Cell Mol Neurobiol. 2008 ;28:923-931.
49. Haas RH Thiamin and the brain. Annu Rev Nutr. 1988 ;8:483-515.
50. Itokawa Y., Schultz RA, Cooper JA Thiamine in nerve membranes. Biochim Biophys Acta. 1972;266:293-299.
51. Matsuda T., Cooper JR Thiamine as an integral component of brain synaptosomal membranes. Proc Natl Acad Sci U S A. 1981;78:5886-5889.
52. Goldberg DJ, Cooper JR Effects of thiamine antagonists on nerve conduction. I. Actions of antimetabolites and fern extract on propagated action potentials. J Neurobiol. 1975;6:435-452.
53. Goldberg DJ, Begenisich TB, Cooper JR Effects of thiamine antagonists on nerve conduction. II. Voltage clamp experiments with antimetabolites. J Neurobiol. 2004;6:453-462.
54. Tanaka C., Itokawa Y., Tanaka S. The axoplasmic transport of thiamine in rat sciatic nerve. J Histochem Cytochem. 1973;21:81-86.
55. Bergquist JE, Hanson M. Axonal transport of thiamine in frog sciatic nerves. Exp Neurol. 1983;79:622-629.
56. Sanjeeva TR, Ramakrishnan CV Effects of thiamine deficiency and undernutrition on the lipid composition of rat spinal cord at 21 days of age. J Neurosci Res. 1983;9:111-114.
57. Terasawa M., Nakahara T., Tsukada N., Sugawara A., Itokawa Y. The relationship between thiamine deficiency and performance of a learning task in rats. Metab Brain Dis. 1999;14:137-148.
58. Claus D., Eggers R., Warecka K., Neundörfer B. Thiamine deficiency and nervous system function disturbances. Eur Arch Psychiatry Neurol Sci. 1985;234:390-394.
59. Ramakrishna T. Vitamins and brain development. Physiol Res. 1999;48:175-187.
60. Georgieff MK Nutrition and the developing brain: nutrient priorities and measurement. Am J Clin Nutr. 2007;85:614S-620S.
61. Fournier H., Butterworth RF Effects of thiamine deficiency on thiamine-dependent enzymes in regions of the brain of pregnant rats and their offspring. Metab Brain Dis. 1990;5:77-84.
62. Trostler N., Guggenheim K., Havivi E., Sklan D. Effect of thiamine deficiency in pregnant and lactating rats on the brain of their offspring. Ann Nutr Metab. 1977;21:294-304.
63. Trostler N., Sklan D. Lipogenesis in the brain of thiamine-deficient rat pups. J Nutr Sci Vitaminol (Tokyo). 1978;24: 105-111.
64. Matsuda T., Doi T., Tonomura H., Baba A., Iwata H. Postnatal development of thiamine metabolism in rat brain. J Neurochem. 1989;52:842-846.
65. Bâ A., N'Douba V., D'Almeida AM, Seri V. Effect of maternal thiamine deficiency on the pyramidal and granule cells of the hippocampus of rat pups. Acta Neurobiol Exp. 2005;65:387-398.
66. Bâ A., Seri BV Psychomotor functions in developing rats: ontogenetic approach to structure-function relationships. Neurosci Biobehav Rev. 1995;19:413-425.
67. Bâ A. Functional vulnerability of developing central nervous system to maternal thiamine deficiencies in the rat. Dev Psychobiol. 2005;47:408-414.
68. Rindi G., Casirola D., Poggi V., De Vizia B., Patrini C., Laforenza U. Thiamine transport by erythrocytes and ghosts in thiamine-responsive megaloblastic anaemia. Inherit Metab Dis. 1992;15: 231-242.
69. Singleton CK, Martin PR Molecular mechanisms of thiamine utilization. Curr Mol Med. 2001;1:197-207.
70. Labay V., Raz T., Baron D.,et al.Mutations in SLC19A2 cause thiamine responsive megaloblastic anaemia associated with diabetes mellitus and deafness. Nat Genet. 1999;22:300-304.
71. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamins. Washington, DC: National Academies Press; 2004.
72. Watson AJ, Walker JF, Tomkin GH, Finn MM, Keogh JA Acute Wernicke's encephalopathy precipitated by glucose loading. Ir J Med Sci. 1981;150:301.
73. Thanangkul O., Whitaker JA, Fort EG Malnutrition in northern Thailand. Am J Clin Nutr. 1966;18:379-389.
74. Tang CM, Rolfe M., Wells JC, Cham K. Outbreak of beri-beri in The Gambia. Lancet. 1989;2:206-207.
75. McGready R., Simpson JA, Cho T.,et al.Postpartum thiamine deficiency in a Karen displaced population. Am J Clin Nutr. 2001;74:808-813.
76. Tallaksen CM, Bøhmer T., Bell H. Blood and serum thiamin and thiamin phosphate esters concentrations in patients with alcohol dependence syndrome before and after thiamin treatment. Alcohol Clin Exp Res. 1992;16:320-325.
77. Hoyumpa AM Jr. Mechanisms of thiamin deficiency in chronic alcoholism. Am J Clin Nutr. 1980;33:2750-2761.
78. Ogershok PR, Rahman A., Nestor S., Brick J. Wernicke encephalopathy in nonalcoholic patients. Am J Med Sci. 2002;323:107-111.
79. Nadel M., Burger PC Wernicke's encephalopathy following prolonged intravenous therapy. JAMA. 1976;235:2403-2405.
80. MacLean LD, Rhode BM, Shizgal HM Nutrition following gastric operations for morbid obesity. Ann Surg. 1983;198:347-355.
81. Drenick EJ, Joven CB, Swendseid ME Occurrence of acute Wernicke's encephalopathy during prolonged starvation for treatment of obesity. New Engl J Med. 1966;274:937-939.
82. Chiossi G., Neri I., Cavazzuti M., Basso G., Facchinetti F. Hyperemesis gravidarum complicated by Wernicke encephalopathy: background, case report, and review of the literature. Obstet Gynecol Surv. 2006; 61:255-268.
83. Handler CE, Perkin GD Anorexia nervosa and Wernicke's encephalopathy: an underdiagnosed association. Lancet. 1982;2:771-772.
84. Lee DC, Chu J., Satz W., Silbergleit R. Low plasma thiamine levels in elder patients admitted through the emergency department. Acad Emerg Med. 2000 ;7:1156-1159.
85. Jamieson CP, Obeid OA, Powell-Tuck J. The thiamin, riboflavin and pyridoxine status of patients on emergency admission to hospital. Clin Nutr. 1999;18:87-91.
86. Seear M., Lockitch G., Jacobson B., Quigley G., MacNab A. Thiamine, riboflavin, and pyridoxine deficiencies in a population of critically ill children. J Pediatr. 1992 ;121:533-538.
87. Centers for Disease Control and Prevention. Lactic acidosis traced to thiamine deficiency related to nationwide shortage of multivitamins for total parenteral nutrition. MMWR Morb Mortal Wkly Rep. 1997;46:523.
88. Alloju M., Ehrinpreis MN Shortage of intravenous multivitamin solution in the United States. New Engl J Med. 1997;337:54.
89. Hahn JS, Berquist W., Alcorn DM, Chamberlain L., Bass D. Wernicke encephalopathy and beriberi during total parenteral nutrition attributable to multivitamin infusion shortage. Pediatrics. 1998; 101:E10.
90. Fattal-Valevski A., Kesler A., Sela B.,et al.Outbreak of life-threatening thiamine deficiency in infants in Israel caused by a defective soy-based formula. Pediatrics. 2005;115:e233-e238.
91. Nishimune T., Watanabe Y., Okazaki H., Akai H. Thiamin is decomposed due to Anaphe spp. entomophagy in seasonal ataxia patients in Nigeria. J Nutr. 2000;130:1625-1628.
92. Brin M. Erythrocyte as a biopsy tissue for functional evaluation of thiamine adequacy. JAMA. 1964;187:762-766.
93. Yamasaki H., Tada H., Kawano S., Aonuma K. Reversible pulmonary hypertension, lactic acidosis, and rapidly evolving multiple organ failure as manifestations of shoshin beriberi. Circ J 2010;74:1983-1985.
94. Korsakoff SS Disturbance of psychic function in alcoholic paralysis and its relationship to disturbance in the psychic sphere in multiple neuritis of non alcoholic origin. Vestnik Psichiatrii. 1887;1V:fasc 2.
95. Vasconcelos MM, Silva KP, Vidal G., Silva AF, Domingues RC, Berditchevsky CR Early diagnosis of pediatric Wernicke's encephalopathy. Pediatr Neurol. 1999;20:289-294.
96. Victor M., Adams RD, Collins GH The Wernicke-Korsakoff syndrome. A clinical and pathological study of 245 patients, 82 with post-mortem examinations. Contemp Neurol Ser. 1971;7:1-206.
97. Langlais PJ, Zhang SX Cortical and subcortical white matter damage without Wernicke's encephalopathy after recovery from thiamine deficiency in the rat. Alcohol Clin Exp Res. 1997;21: 434-443.
98. Zhong C., Jin L., Fei G. MR imaging of nonalcoholic Wernicke encephalopathy: a follow-up study. AJNR Am J Neuroradiol. 2005;26:2301-2305.