Cationic amino acid uptake constitutes a metabolic regulation mechanism and occurs in the flagellar pocket of trypanosoma cruzi

PLoS ONE

Volumn 7, Issue 2, 2012, Pages

  Miranda, Mariana R ^a   Sayé, Melisa ^a   Bouvier, León A ^a   de los Milagros Cámara, María ^a   Montserrat, Javier ^b   Pereira, Claudio A ^a  

^a INSTITUTO DE INVESTIGACIONES MÉDICAS ALFREDO LANARI   (Argentina)

^b INSTITUTO DE INVESTIGACIONES EN INGENIERÍA GENÉTICA Y BIOLOGÍA MOLECULAR   (Argentina)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; AMINO ACID TRANSPORTER; ARGININE; ARGININE KINASE; GLUCOSE; TRYPANOSOMA CRUZI AMINO ACID AUXIN PERMEASE 3; TRYPANOSOMA CRUZI AMINO ACID AUXIN PERMEASE 7; UNCLASSIFIED DRUG; AMINO ACID; CATION; LYSINE;

AMINO ACID METABOLISM; AMINO ACID TRANSPORT; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL MEMBRANE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DOWN REGULATION; ENZYME REGULATION; ENZYME SPECIFICITY; ENZYME SUBSTRATE; EPIMASTIGOTE; FLAGELLAR POCKET; GENE; GENE OVEREXPRESSION; IMMUNOFLUORESCENCE TEST; IN VIVO GENE TRANSFER; NONHUMAN; PARASITE DEVELOPMENT; PROTEIN LOCALIZATION; TRYPANOSOMA CRUZI; TRYPANOSOMA CRUZI AMINO ACID AUXIN PERMEASE 3 GENE; TRYPANOSOMA CRUZI AMINO ACID AUXIN PERMEASE 7 GENE; WESTERN BLOTTING; BIOLOGY; CHEMISTRY; FLAGELLUM; FLUORESCENCE MICROSCOPY; GENETICS; HUMAN; METABOLISM; METHODOLOGY; PHYSIOLOGY; PLASMID; TRANSPORT AT THE CELLULAR LEVEL;

EUKARYOTA; TRYPANOSOMA CRUZI; TRYPANOSOMATIDAE;

ADENOSINE TRIPHOSPHATE; AMINO ACIDS; ARGININE; ARGININE KINASE; BIOLOGICAL TRANSPORT; CATIONS; COMPUTATIONAL BIOLOGY; DOWN-REGULATION; FLAGELLA; HUMANS; LYSINE; MICROSCOPY, FLUORESCENCE; PLASMIDS; SUBSTRATE SPECIFICITY; TRYPANOSOMA CRUZI;

EID: 84857665793     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0032760     Document Type: Article

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