Description and plasmid characterization of qnrD determinants in Proteus mirabilis and Morganella morganii

Clinical Microbiology and Infection

Volumn 18, Issue 3, 2012, Pages

  Mazzariol, A ^a   Kocsis, B ^a,b   Koncan, R ^a   Kocsis, E ^a   Lanzafame, P ^c   Cornaglia, G ^a  

^a UNIVERSITY OF VERONA   (Italy)

^b SEMMELWEIS UNIVERSITY OF MEDICINE   (Hungary)

^c Azienda Provinciale Per I Servizi Sanitari   (Italy)

Author keywords

Fluoroquinolone resistance; Morganella morganii; Plasmid mediated fluoroquinolone resistance determinants; Proteus mirabilis; qnrD

Indexed keywords

PLASMID DNA;

ARTICLE; BACTERIAL GENE; BACTERIUM GENE QNRD; BACTERIUM ISOLATE; BASE PAIRING; GENE FREQUENCY; GENE IDENTIFICATION; GENE LOCATION; GENE SEQUENCE; GENETIC CODE; MORGANELLA MORGANII; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEUS MIRABILIS;

ENTEROBACTERIACEAE; MORGANELLA MORGANII; PROTEUS MIRABILIS;

EID: 84857640673     PISSN: 1198743X     EISSN: 14690691     Source Type: Journal    
DOI: 10.1111/j.1469-0691.2011.03728.x     Document Type: Article

References (20)

1. Strahilevitz J, Jacoby GA, Hooper DC, Robicsek A. Plasmid mediated quinolone resistance: a multifaceted threat. Clin Microbiol Rev 2009; 22: 664-689.
2. Martinez-Martinez L, Pascual A, Jacoby GA. Quinolone resistance from a transferable plasmid. Lancet 1998; 351: 797-799.
3. Jacoby GA, Wash KE, Mills DM et al. qnrB, another plasmid-mediated gene for quinolone resistance. Antimicrob Agents Chemother 2006; 50: 1178-1182.
4. Hata M, Suzuki M, Matsumoto M et al. Cloning of a nove gene for quinolone resistance from a transferable plasmid in Shigella flexneri 2b. Antimicrob Agents Chemother 2005; 49: 801-803.
5. Wang M, Guo Q, Xu X et al. New plasmid-mediated quinolone resistance gene, qnrC, found in a clinical isolate of Proteus mirabilis. Antimicrob Agents Chemother 2009; 53: 1892-1897.
6. Cavaco LM, Hasman H, Xia S, Aarestrup FM. qnrD, a novel gene conferring transferable quinolone resistance in Salmonella enterica Serovar Kentucky and bovismorbificans strains of human origin. Antimicrob Agents Chemother 2009; 58: 603-608.
7. Fonseca EL, Dos Santos Freitas F, Vieira VV, Vicente ACP. New qnr gene cassettes associated with superintegron repeats in Vibrio cholerae. Emerg Infect Dis 2008; 14: 1129-1131.
8. Zhao J, Chen Z, Chen S et al. Prevalence and dissemination of oqxAB in Escherichia coli isolates from animals, farmworkers, and the environment. Antimicrob Agents Chemother 2010; 54: 4219-4224.
9. Ogbolu DO, Daini OA, Ogunledun A, Alli AO, Webber MA. High levels of multidrug resistance in clinical isolates of Gram-negative pathogens from Nigeria. Int J Antimicrob Agents 2011; 37: 62-66.
10. Koncan R, Mazzariol A, Kocsis B et al. First detection in Europe of plasmid-mediated fluoroquinolone resistance qnrD determinant. Clin Microbiol Infect 2010; 16: S126.
11. Veldman K, Cavaco LM, Mevius D et al. International collaborative study on the occurrence of plasmid-mediated quinolone resistance in Salmonella enterica and Escherichia coli isolated from animals, humans, food and the environment in 13 European countries. J Antimicrob Chemother 2011; 66: 1278-1286.
12. Robicsek A, Strahilevitz J, Sahm DF, Jacoby GA, Hooper DC. qnr prevalence in ceftazidime-resistant Enterobacteriaceae isolates from the United States. Antimicrob Agents Chemother 2006; 50: 2872-2874.
13. Park CH, Robicsek A, Jacoby GA, Sahm D, Hooper DC. Prevalence in the United States of aac(6′)-Ib-cr encoding a ciprofloxacin-modifying enzyme. Antimicrob Agents Chemother 2006; 50: 3953-3955.
14. Yamane K, Wachino J, Suzuki S, Arakawa Y. Plasmid mediated qepA gene among Escherichia coli clinical isolates from Japan. Antimicrob Agents Chemother 2008; 52: 1564-1566.
15. Sambrook J, Fritsch EF, Maniatis T. Molecular cloning: a laboratory manual, 2nd edn. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory, 1989.
16. Carattoli A, Bertini A, Villa L et al. Identification of plasmids by PCR-based replicon typing. J Microbiol Methods 2005; 63: 219-228.
17. García-Fernández A, Fortini D, Veldman K, Mevius D, Carattoli A. Characterization of plasmids harbouring qnrS1, qnrB2 and qnrB19 genes in Salmonella. J Antimicrob Chemother 2009; 63: 274-281.
18. Weigel LM, Anderson GJ, Tenover FC. DNA gyrase and topoisomerase IV mutations associated with fluoroquinolone resistance in Proteus mirabilis. Antimicrob Agents Chemother 2002; 46: 2582-2587.
19. Maurin M, Abergel C, Raoult D. DNA gyrase-mediated natural resistance to fluoroquinolones in Ehrlichia spp. Antimicrob Agents Chemother 2001; 45: 2098-2105.
20. Michelim L, Muller G, Zacaria J, Longaray Delamare AP, Pinto da Costa SO, Echeverrigaray S. Comparison of PCR-based molecular markers for the characterization of Proteus mirabilis clinical isolates. Braz J Infect Dis 2008; 12: 423-429.