Novel insights into the pathomechanisms of skeletal muscle channelopathies

Current Neurology and Neuroscience Reports

Volumn 12, Issue 1, 2012, Pages 62-69

  Burge, James A ^a,b   Hanna, Michael G ^a,b  

^a NATIONAL HOSPITAL FOR NEUROLOGY AND NEUROSURGERY   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Andersen Tawil; Bistability; Channel; Channelopathy; Chloride; Electrophysiology; Hyperkalemic; Hypokalemic; Muscle; Myotonia; Periodic paralysis; Potassium; Skeletal; Sodium

Indexed keywords

CALCIUM CHANNEL L TYPE; CHLORIDE CHANNEL; INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT KIR2.1; POTASSIUM; SODIUM CHANNEL NAV1.4;

CACNA1S GENE; CELL MEMBRANE DEPOLARIZATION; CLCN1 GENE; CLINICAL FEATURE; DISEASE SEVERITY; GAIN OF FUNCTION MUTATION; GENE; GENE MUTATION; HEART ARRHYTHMIA; HUMAN; HYPERKALEMIA; HYPOKALEMIC PERIODIC PARALYSIS; KCNJ18 GENE; KCNJ2 GENE; MEDICAL DECISION MAKING; MUSCLE CHANNELOPATHY; MYOPATHY; MYOTONIA; NONHUMAN; PARALYSIS; PATHOGENESIS; PATHOPHYSIOLOGY; PERIODIC PARALYSIS; PHENOTYPIC VARIATION; POTASSIUM AGGRAVTED MYOTONIA; REVIEW; SCN4A GENE; SEVERE NEONATAL EPISODIC LARYNGOSPASM; THOMSEN DISEASE;

ANIMALS; ARRHYTHMIAS, CARDIAC; CHANNELOPATHIES; HUMANS; HYPOKALEMIC PERIODIC PARALYSIS; ION CHANNELS; MUSCLE, SKELETAL; MUTATION; MYOTONIC DISORDERS; PARALYSIS, HYPERKALEMIC PERIODIC;

EID: 84857628860     PISSN: 15284042     EISSN: 15346293     Source Type: Journal    
DOI: 10.1007/s11910-011-0238-3     Document Type: Review

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