Low-dose cardiovascular computed tomography: Where are the limits?

Current Cardiology Reports

Volumn 14, Issue 1, 2012, Pages 17-23

  Schoenhagen, Paul ^a,b   Thompson, Carla M ^a,b   Halliburton, Sandra S ^a,b  

^a LERNER RESEARCH INSTITUTE   (United States)

^b CLEVELAND STATE UNIVERSITY   (United States)

Author keywords

Cancer; Cardiovascular imaging; Computed tomography; Dose saving; Radiation exposure; X ray

Indexed keywords

ARTICLE; CANCER RISK; CARDIOVASCULAR DISEASE; COMPUTED TOMOGRAPHIC ANGIOGRAPHY; COMPUTER ASSISTED TOMOGRAPHY; DIAGNOSTIC VALUE; ELECTROCARDIOGRAPHY; EQUIPMENT DESIGN; EVIDENCE BASED MEDICINE; HUMAN; IMAGE QUALITY; IMAGE RECONSTRUCTION; MULTICENTER STUDY (TOPIC); MULTIDETECTOR COMPUTED TOMOGRAPHY; NOISE REDUCTION; PATIENT CARE; RADIATION DOSE; RADIATION EXPOSURE; TECHNOLOGY;

AGE FACTORS; BODY MASS INDEX; CORONARY ANGIOGRAPHY; CORONARY ARTERY DISEASE; DOSE-RESPONSE RELATIONSHIP, RADIATION; FEMALE; HUMANS; MALE; NEOPLASMS, RADIATION-INDUCED; RADIATION DOSAGE; RISK FACTORS; TOMOGRAPHY, X-RAY COMPUTED;

EID: 84857625701     PISSN: 15233782     EISSN: 15343170     Source Type: Journal    
DOI: 10.1007/s11886-011-0225-y     Document Type: Article

References (46)

1. GN Hounsfield 1980 Computed medical imaging Science 210 22 8 6997993 10.1126/science.6997993 1:STN:280:DyaL3M%2FhsFClsg%3D%3D (Pubitemid 11192047)
2. TN Raju 1999 The Nobel chronicles. 1979: Allan MacLeod Cormack (b 1924); and Sir Godfrey Newbold Hounsfield (b 1919) Lancet. 354 1653 10560712 10.1016/S0140-6736(05)77147-6 1:STN:280:DC%2BD3c%2Fitlelug%3D%3D
3. LR Goodman 2010 The Beatles, the Nobel Prize, and CT scanning of the chest Radiol Clin North Am. 48 1 7 19995626 10.1016/j.rcl.2009.09.008
4. JW McEvoy MJ Blaha K Nasir YE Yoon EK Choi IS Cho EJ Chun SI Choi JJ Rivera RS Blumenthal HJ Chang 2011 Impact of coronary computed tomographic angiography results on patient and physician behavior in a low-risk population Arch Intern Med. 171 1260 8 21606093 10.1001/archinternmed.2011.204
5. • Einstein AJ, Henzlova MJ, Rajagopalan S. Estimating risk of cancer associated with radiation exposure from 64-slice computed tomography coronary angiography. JAMA 2007; 298:317-23. This is an important paper that focused the field of cardiovascular CT imaging on radiation exposure. (Pubitemid 47080486)
6. Berrington de González A, Mahesh M, Kim KP, et al. Projected cancer risks from computed tomographic scans performed in the United States in 2007. Arch Intern Med 2009; 169:2071-2077.
7. • Brenner DJ, Hall EJ. Computed tomography - an increasing source of radiation exposure. N Engl J Med 2007; 357:2277-84. This is an important paper that focused the field of cardiovascular CT imaging on radiation exposure. (Pubitemid 350190758)
8. FA Mettler M Bhargavan K Faulkner, et al. 2009 Radiologic and nuclear medicine studies in the United States and worldwide: frequency, radiation dose, and comparison with other radiation sources-1950-2007 Radiology 253 520 531 19789227 10.1148/radiol.2532082010
9. R Fazel HM Krumholz Y Wang, et al. 2009 Exposure to low-dose ionizing radiation from medical imaging procedures N Engl J Med 361 849 857 19710483 10.1056/NEJMoa0901249 1:CAS:528:DC%2BD1MXhtVKhtL7M
10. FA Mettler W Huda TT Yoshizumi M Mahesh 2008 Effective doses in radiology and diagnostic nuclear medicine: a catalog Radiology 248 254 263 18566177 10.1148/radiol.2481071451
11. TC Gerber JJ Carr AE Arai RL Dixon VA Ferrari AS Gomes GV Heller CH McCollough MF McNitt-Gray FA Mettler JH Mieres RL Morin MV Yester 2009 Ionizing radiation in cardiac imaging: a science advisory from the American Heart Association Committee on Cardiac Imaging of the Council on Clinical Cardiology and Committee on Cardiovascular Imaging and Intervention of the Council on Cardiovascular Radiology and Intervention Circulation. 119 1056 65 19188512 10.1161/CIRCULATIONAHA.108.191650
12. W Huda FA Mettler 2011 Volume CT dose index and dose-length product displayed during CT: what good are they? Radiology. 258 236 42 20971777 10.1148/radiol.10100297
13. Bongartz G, Golding SJ, Jurik AG, Leonardi M, van Meerten EvP, Rodríguez R, Schneider K, Calzado A, Geleijns J, Jessen KA, W. Panzer, Shrimpton PCT, G.. European Guidelines for Multislice Computed Tomography Funded by the European Commission. Contract number FIGM-CT2000-20078-CT-TIP 2004.
14. McCollough C, Cody D, Edyvean S, Geise R, Gould B, Keat N, Huda W, Judy P, Kalender W, McNitt-Gray M, Morin R, Payne T, Stern S, Rothenberg L, Shrimpton P, Timmer J, Wilson C. The Measurement, Reporting, and Management of Radiation Dose in CT Report of AAPM Task Group 23 of the Diagnostic Imaging Council CT Committee, 2008:1-28.
15. AJ Einstein CD Elliston AE Arai MY Chen R Mather GD Pearson RL Delapaz E Nickoloff A Dutta DJ Brenner 2010 Radiation dose from single-heartbeat coronary CT angiography performed with a 320-detector row volume scanner Radiology 254 698 706 20177085 10.1148/radiol.09090779
16. J Geleijns RM Joemai M Dewey A de Roos M Zankl AC Cantera MS Artells 2011 Radiation exposure to patients in a multicenter coronary angiography trial (CORE 64) AJR Am J Roentgenol 196 1126 32 21512080 10.2214/AJR.09.3983
17. R Smith-Bindman J Lipson R Marcus KP Kim M Mahesh R Gould A Berrington de Gonzalez DL Miglioretti 2009 Radiation dose associated with common computed tomography examinations and the associated lifetime attributable risk of cancer Arch Intern Med 169 2078 86 20008690 10.1001/archinternmed.2009.427
18. J Strzelczyk J Damilakis MV Marx KJ Macura 2007 Facts and controversies about radiation exposure, part 2: low-level exposures and cancer risk J Am Coll Radiol 4 32 39 17412222 10.1016/j.jacr.2006.07.010 (Pubitemid 46014512)
19. M Tubiana LR Feinendegen C Yang JM Kaminski 2009 The linear no-threshold relationship is inconsistent with radiation biologic and experimental data Radiology 251 13 22 19332842 10.1148/radiol.2511080671
20. MP Little R Wakeford EJ Tawn SD Boufffler A Berrington de Gonzalez 2009 Risks associated with low doses or low dose rates of ionizing radiation: why linearity may be (almost) the best we can do Radiology 251 6 12 19332841 10.1148/radiol.2511081686
21. J Rixe G Conradi A Rolf A Schmermund A Magedanz D Erkapic A Deetjen CW Hamm T Dill 2009 Radiation dose exposure of computed tomography coronary angiography: comparison of dual-source, 16-slice and 64-slice CT Heart. 95 1337 42 19482842 10.1136/hrt.2008.161018 1:STN:280:DC%2BD1Mrhs1SksQ%3D%3D
22. • Hausleiter J, Meyer T, Hermann F, Hadamitzky M, Krebs M, Gerber TC, McCollough C, Martinoff S, Kastrati A, Schömig A, Achenbach S. Estimated radiation dose associated with cardiac CT angiography. JAMA. 2009;301:500-7. This is an important paper that demonstrated the wide variation of radiation exposure in cardiovascular CT.
23. B Bischoff F Hein T Meyer M Krebs M Hadamitzky S Martinoff A Schömig J Hausleiter 2010 Comparison of sequential and helical scanning for radiation dose and image quality: results of the Prospective Multicenter Study on Radiation Dose Estimates of Cardiac CT Angiography (PROTECTION) I Study AJR Am J Roentgenol. 194 1495 9 20489088 10.2214/AJR.09.3543
24. J Hausleiter S Martinoff M Hadamitzky E Martuscelli I Pschierer GM Feuchtner P Catalán-Sanz B Czermak TS Meyer F Hein B Bischoff M Kuse A Schömig S Achenbach 2010 Image quality and radiation exposure with a low tube voltage protocol for coronary CT angiography results of the PROTECTION II Trial JACC Cardiovasc Imaging. 3 1113 23 21070998 10.1016/j.jcmg.2010.08.016
25. B Bischoff F Hein T Meyer M Hadamitzky S Martinoff A Schömig J Hausleiter 2009 Impact of a reduced tube voltage on CT angiography and radiation dose: results of the PROTECTION I study JACC Cardiovasc Imaging. 2 940 6 19679281 10.1016/j.jcmg.2009.02.015
26. • Husmann L, Valenta I, Gaemperli O et al.: Feasibility of low-dose coronary CT angiography: first experience with prospective ECG-gating. Eur. Heart J. 2008; 29, 191-197. This is an important early paper that described one of the most effective dose-saving techniques.
27. S Leschka P Stolzmann FT Schmid H Scheffel B Stinn B Marincek H Alkadhi S Wildermuth 2008 Low kilovoltage cardiac dual-source CT: attenuation, noise, and radiation dose Eur Radiol. 18 1809 17 18392829 10.1007/s00330-008-0966-1
28. P Blanke T Baumann M Langer G Pache 2010 Imaging of pulmonary vein anatomy using low-dose prospective ECG-triggered dual-source computed tomography Eur Radiol. 74 354 352
29. P Blanke S Bulla T Baumann M Siepe JT Winterer W Euringer AO Schäfer E Kotter M Langer G Pache 2010 Thoracic aorta: prospective electrocardiographically triggered CT angiography with dual-source CT-feasibility, image quality, and dose reduction Radiology. 255 207 17 20160003 10.1148/radiol.09090860
30. Leipsic J, Heilbron BG, Hague C. Iterative reconstruction for coronary CT angiography: finding its way. Int J Cardiovasc Imaging. 2011 Feb 27. [Epub ahead of print]
31. J Leipsic TM Labounty B Heilbron JK Min GB Mancini FY Lin C Taylor A Dunning JP Earls 2010 Adaptive statistical iterative reconstruction: assessment of image noise and image quality in coronary CT angiography AJR Am J Roentgenol. 195 649 54 20729442 10.2214/AJR.10.4285
32. J Leipsic TM Labounty B Heilbron JK Min GB Mancini FY Lin C Taylor A Dunning JP Earls 2010 Estimated radiation dose reduction using adaptive statistical iterative reconstruction in coronary CT angiography: the ERASIR study AJR Am J Roentgenol. 195 655 60 20729443 10.2214/AJR.10.4288
33. J Leipsic G Nguyen J Brown D Sin JR Mayo 2010 A prospective evaluation of dose reduction and image quality in chest CT using adaptive statistical iterative reconstruction AJR Am J Roentgenol. 195 1095 9 20966312 10.2214/AJR.09.4050
34. K Perisinakis I Seimenis A Tzedakis AE Papadakis J Damilakis 2010 Individualized assessment of radiation dose in patients undergoing coronary computed tomographic angiography with 256-slice scanning Circulation. 122 1033 1034 10.1161/CIRCULATIONAHA.109.935346
35. S Achenbach M Marwan D Ropers, et al. 2010 Coronary computed tomography angiography with a consistent dose below 1 mSv using prospectively electrocardiogram-triggered high-pitch spiral acquisition Eur Heart J 31 340 346 19897497 10.1093/eurheartj/ehp470
36. RR Buechel L Husmann BA Herzog AP Pazhenkottil R Nkoulou JR Ghadri V Treyer P von Schulthess PA Kaufmann 2011 Low-dose computed tomography coronary angiography with prospective electrocardiogram triggering feasibility in a large population J Am Coll Cardiol. 57 332 336 21232672 10.1016/j.jacc.2010.08.634
37. MW von Ballmoos B Haring P Juillerat H Alkadhi 2011 Meta-analysis: diagnostic performance of low-radiation-dose coronary computed tomography angiography Ann Intern Med 154 848
38. GL Raff KM Chinnaiyan DA Share TY Goraya EA Kazerooni M Moscucci RE Gentry A Abidov 2009 Radiation dose from cardiac computed tomography before and after implementation of radiation dose-reduction techniques JAMA 301 2340 2348 19509381 10.1001/jama.2009.814 1:CAS:528:DC%2BD1MXntFCms70%3D
39. RC Hendel MR Patel CM Kramer ACCF/ACR/SCCT/SCMR/ASNC/NASCI/SCAI/SIR, et al. 2006 Appropriateness criteria for cardiac computed tomography and cardiac magnetic resonance imaging: a report of the American College of Cardiology Foundation Quality Strategic Directions Committee Appropriateness Criteria Working Group, American College of Radiology, Society of Cardiovascular Computed Tomography, Society for Cardiovascular Magnetic Resonance, American Society of Nuclear Cardiology, North American Society for Cardiac Imaging, Society for Cardiovascular Angiography and Interventions, and the Society of Interventional Radiology J Am Coll Cardiol 48 1475 1497 17010819 10.1016/j.jacc.2006.07.003
40. AJ Taylor M Cerqueira JM Hodgson D Mark J Min P O'Gara GD Rubin CM Kramer D Berman A Brown FA Chaudhry RC Cury MY Desai AJ Einstein AS Gomes R Harrington U Hoffmann R Khare J Lesser C McGann A Rosenberg R Schwartz M Shelton GW Smetana J Smith S. C. ACCF/SCCT/ACR/AHA/ASE/ASNC/NASCI/SCAI/SCMR 2010 Appropriate Use Criteria for Cardiac Computed Tomography: A Report of the American College of Cardiology Foundation Appropriate Use Criteria Task Force, the Society of Cardiovascular Computed Tomography, the American College of Radiology, the American Heart Association, the American Society of Echocardiography, the American Society of Nuclear Cardiology, the North American Society for Cardiovascular Imaging, the Society for Cardiovascular Angiography and Interventions, and the Society for Cardiovascular Magnetic Resonance. J Cardiovasc Comput Tomogr 56 1864 1894
41. A Christe JC Torrente M Lin A Yen R Hallett K Roychoudhury F Schmitzberger P Vock J Roos 2011 CT screening and follow-up of lung nodules: effects of tube current-time setting and nodule size and density on detectability and of tube current-time setting on apparent size AJR Am J Roentgenol. 197 3 623 30 21862804 10.2214/AJR.10.5288
42. Wang D, Hu XH, Zhang SZ, et al. Image quality and dose performance of 80 kV low dose scan protocol in high-pitch spiral coronary CT angiography: feasibility study. Imaging: Int. J. Cardiovasc; 2011.
43. KT Ho KC Chua E Klotz C Panknin 2010 Stress and rest dynamic myocardial perfusion imaging by evaluation of complete time-attenuation curves with dual-source CT.JACC Cardiovasc Imaging. 3 811 20
44. Schoenhagen P, Hausleiter J, Achenbach S, Y. Desai M, Tuzcu EM. Computed Tomography in the Evaluation for Transcatheter Aortic Valve Implantation (TAVI). Cardiovasc Diagn Ther 2011 Aug 29. doi: 10.3978/j.issn.2223-3652.2011.08.01
45. G Feuchtner R Goetti A Plass S Baumueller P Stolzmann H Scheffel M Wieser B Marincek H Alkadhi S Leschka 2010 Dual-step prospective ECG-triggered 128-slice dual-source CT for evaluation of coronary arteries and cardiac function without heart rate control: a technical note Eur Radiol. 20 2092 9 20407896 10.1007/s00330-010-1794-7
46. P Schoenhagen R Hachamovitch S Achenbach 2011 Coronary CT angiography and comparative effectiveness research prognostic value of atherosclerotic disease burden in appropriately indicated clinical examinations JACC Cardiovasc Imaging. 4 492 5 21565736 10.1016/j.jcmg.2011.02.013