메뉴 건너뛰기




Volumn 15, Issue 3, 2012, Pages 253-257

Phloretin inhibits phorbol ester-induced tumor promotion and expression of cyclooxygenase-2 in mouse skin: Extracellular signal-regulated kinase and nuclear factor-κB as potential targets

Author keywords

Chemoprevention; Cyclooxygenase 2; Mouse skin carcinogenesis; Nuclear factor B; Phloretin

Indexed keywords

CYCLOOXYGENASE 2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PHLORETIN; PHORBOL 13 ACETATE 12 MYRISTATE; PHORBOL ESTER;

EID: 84857575682     PISSN: 1096620X     EISSN: 15577600     Source Type: Journal    
DOI: 10.1089/jmf.2011.1851     Document Type: Article
Times cited : (17)

References (20)
  • 2
    • 0038460053 scopus 로고    scopus 로고
    • Carcinogenesis and cyclooxygenase: The potential role of COX-2 inhibition in upper aerodigestive tract cancer
    • DOI 10.1016/S1368-8375(03)00035-6
    • Mohan S, Epstein JB: Carcinogenesis and cyclooxygenase: the potential role of COX-2 inhibition in upper aerodigestive tract cancer. Oral Oncol 2003;39:537-546. (Pubitemid 36700424)
    • (2003) Oral Oncology , vol.39 , Issue.6 , pp. 537-546
    • Mohan, S.1    Epstein, J.B.2
  • 3
    • 0037126069 scopus 로고    scopus 로고
    • Transgenic cyclooxygenase-2 overexpression sensitizes mouse skin for carcinogenesis
    • Muller-Decker K, Neufang G, Berger I, et al.: Transgenic cyclooxygenase-2 overexpression sensitizes mouse skin for carcinogenesis. Proc Natl Acad Sci USA 2002;99:12483-12488.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 12483-12488
    • Muller-Decker, K.1    Neufang, G.2    Berger, I.3
  • 5
    • 20344381337 scopus 로고    scopus 로고
    • Signal transduction network leading to COX-2 induction: A road map in search of cancer chemopreventives
    • DOI 10.1007/BF02975128
    • Surh YJ, Kundu JK: Signal transduction network leading to COX-2 induction: a road map in search of cancer chemopreventives. Arch Pharm Res 2005;28:1-15. (Pubitemid 44698760)
    • (2005) Archives of Pharmacal Research , vol.28 , Issue.1 , pp. 1-15
    • Surh, Y.-J.1    Kundu, J.K.2
  • 6
    • 0036279287 scopus 로고    scopus 로고
    • Anti-tumor promoting potential of selected spice ingredients with antioxidative and anti-inflammatory activities: A short review
    • Surh YJ: Anti-tumor promoting potential of selected spice ingredients with antioxidative and anti-inflammatory activities: a short review. Food Chem Toxicol 2002;40:1091-1097.
    • (2002) Food Chem Toxicol , vol.40 , pp. 1091-1097
    • Surh, Y.J.1
  • 8
    • 37549033823 scopus 로고    scopus 로고
    • Induction of apoptosis in HT-29 colon cancer cells by phloretin
    • Park SY, Kim EJ, Shin HK, et al.: Induction of apoptosis in HT-29 colon cancer cells by phloretin. J Med Food 2007;10:581-586.
    • (2007) J Med Food , vol.10 , pp. 581-586
    • Park, S.Y.1    Kim, E.J.2    Shin, H.K.3
  • 9
    • 69149092832 scopus 로고    scopus 로고
    • Phloretin induces apoptosis in H-Ras MCF10A human breast tumor cells through the activation of p53 via JNK and p38 mitogen-activated protein kinase signaling
    • Kim MS, Kwon JY, Kang NJ, et al.: Phloretin induces apoptosis in H-Ras MCF10A human breast tumor cells through the activation of p53 via JNK and p38 mitogen-activated protein kinase signaling. Ann NY Acad Sci 2009;1171:479-483.
    • (2009) Ann NY Acad Sci , vol.1171 , pp. 479-483
    • Kim, M.S.1    Kwon, J.Y.2    Kang, N.J.3
  • 10
    • 0021745750 scopus 로고
    • Calcium and phospholipid-dependent protein kinase activity in mouse epidermis cytosol. Stimulation by complete and incomplete tumor promoters and inhibition by various compounds
    • Gschwendt M, Horn F, Kittstein W, et al.: Calcium and phospholipid-dependent protein kinase activity in mouse epidermis cytosol. Stimulation by complete and incomplete tumor promoters and inhibition by various compounds. Biochem Biophys Res Commun 1984;124:63-68. (Pubitemid 15207661)
    • (1984) Biochemical and Biophysical Research Communications , vol.124 , Issue.1 , pp. 63-68
    • Gschwendt, M.1    Horn, F.2    Kittstein, W.3
  • 11
    • 0029583462 scopus 로고
    • Effects of prostaglandin antagonist phloretin derivatives on mouse ear edema induced with different skin irritants
    • DOI 10.1016/0090-6980(95)00109-3
    • Blazso G, Gabor M: Effects of prostaglandin antagonist phloretin derivatives on mouse ear edema induced with different skin irritants. Prostaglandins 1995;50:161-168. (Pubitemid 26002135)
    • (1995) Prostaglandins , vol.50 , Issue.3 , pp. 161-168
    • Blazso, G.1    Gabor, M.2
  • 12
    • 0023006863 scopus 로고
    • Inhibition of biological actions of 12-O-tetradecanoylphorbol-13-acetate by inhibitors of protein kinase C
    • Tanaka K, Ono T, Umeda M: Inhibition of biological actions of 12-O-tetradecanoylphorbol-13-acetate by inhibitors of protein kinase C. Jpn J Cancer Res 1986;77:1107-1113. (Pubitemid 17210039)
    • (1986) Japanese Journal of Cancer Research , vol.77 , Issue.11 , pp. 1107-1113
    • Tanaka, K.1    Ono, T.2    Umeda, M.3
  • 14
    • 0035953182 scopus 로고    scopus 로고
    • Capsaicin suppresses phorbol ester-induced activation of NF-κB/Rel and AP-1 transcription factors in mouse epidermis
    • DOI 10.1016/S0304-3835(01)00378-0, PII S0304383501003780
    • Han SS, Keum YS, Seo HJ, et al.: Capsaicin suppresses phorbol ester-induced activation of NF-κB/Rel and AP-1 transcription factors in mouse epidermis. Cancer Lett 2001;164:119-126. (Pubitemid 32155498)
    • (2001) Cancer Letters , vol.164 , Issue.2 , pp. 119-126
    • Han, S.S.1    Keum, Y.-S.2    Seo, H.-J.3    Chun, K.-S.4    Lee, S.S.5    Surh, Y.-J.6
  • 15
    • 0142166328 scopus 로고    scopus 로고
    • Cancer chemoprevention with dietary phytochemicals
    • Surh YJ: Cancer chemoprevention with dietary phytochemicals. Nat Rev Cancer 2003;3:768-780.
    • (2003) Nat Rev Cancer , vol.3 , pp. 768-780
    • Surh, Y.J.1
  • 16
    • 0033517718 scopus 로고    scopus 로고
    • Transcriptional regulation of the cyclooxygenase-2 gene by diverse ligands in murine osteoblasts
    • Wadleigh DJ, Herschman HR: Transcriptional regulation of the cyclooxygenase-2 gene by diverse ligands in murine osteoblasts. Biochem Biophys Res Commun 1999;264:865-870.
    • (1999) Biochem Biophys Res Commun , vol.264 , pp. 865-870
    • Wadleigh, D.J.1    Herschman, H.R.2
  • 17
    • 0032538428 scopus 로고    scopus 로고
    • Transcriptional regulation of cyclooxygenase-2 in mouse skin carcinoma cells: Regulatory role of CCAAT/enhancer-binding proteins in the differential expression of cyclooxygenase-2 in normal and neoplastic tissues
    • DOI 10.1074/jbc.273.42.27686
    • Kim Y, Fischer SM: Transcriptional regulation of cyclooxygenase-2 in mouse skin carcinoma cells. Regulatory role of CCAAT/enhancer-binding proteins in the differential expression of cyclooxygenase-2 in normal and neoplastic tissues. J Biol Chem 1998;273:27686-27694. (Pubitemid 28500494)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.42 , pp. 27686-27694
    • Kim, Y.1    Fischer, S.M.2
  • 18
    • 0037147201 scopus 로고    scopus 로고
    • Salicylate suppresses macrophage nitric-oxide synthase-2 and cyclo-oxygenase-2 expression by inhibiting CCAAT/enhancer-binding protein-beta binding via a common signaling pathway
    • DOI 10.1074/jbc.M205030200
    • Cieslik K, Zhu Y, Wu KK: Salicylate suppresses macrophage nitric-oxide synthase-2 and cyclo-oxygenase-2 expression by inhibiting CCAAT/enhancer-binding protein-beta binding via a common signaling pathway. J Biol Chem 2002;277:49304-49310. (Pubitemid 36014360)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.51 , pp. 49304-49310
    • Cieslik, K.1    Zhu, Y.2    Wu, K.K.3
  • 19
    • 0141814600 scopus 로고    scopus 로고
    • Curcumin inhibits phorbol ester-induced expression of cyclooxygenase-2 in mouse skin through suppression of extracellular signal-regulated kinase activity and NF-κB activation
    • DOI 10.1093/carcin/bgg107
    • Chun KS, Keum YS, Han SS, et al.: Curcumin inhibits phorbol ester-induced expression of cyclooxygenase-2 in mouse skin through suppression of extracellular signal-regulated kinase activity and NF-κB activation. Carcinogenesis 2003;24:1515-1524. (Pubitemid 37160842)
    • (2003) Carcinogenesis , vol.24 , Issue.9 , pp. 1515-1524
    • Chun, K.-S.1    Keum, Y.-S.2    Han, S.S.3    Song, Y.-S.4    Kim, S.-H.5    Surh, Y.-J.6
  • 20
    • 4143124753 scopus 로고    scopus 로고
    • Signal transduction pathways regulating cyclooxygenase-2 expression: Potential molecular targets for chemoprevention
    • Chun KS, Surh YJ: Signal transduction pathways regulating cyclooxygenase-2 expression: potential molecular targets for chemoprevention. Biochem Pharmacol 2004;68:1089-1100.
    • (2004) Biochem Pharmacol , vol.68 , pp. 1089-1100
    • Chun, K.S.1    Surh, Y.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.