-
1
-
-
33748323383
-
Regulation of cardiac hypertrophy by intracellular signalling pathways
-
DOI 10.1038/nrm1983, PII NRM1983
-
Heineke J, Molkentin JD. Regulation of cardiac hypertrophy by intracellular signalling pathways. Nat Rev Mol Cell Biol. 2006;7:589-600. (Pubitemid 44325350)
-
(2006)
Nature Reviews Molecular Cell Biology
, vol.7
, Issue.8
, pp. 589-600
-
-
Heineke, J.1
Molkentin, J.D.2
-
2
-
-
14344279280
-
A cardiac myocyte vascular endothelial growth factor paracrine pathway is required to maintain cardiac function
-
DOI 10.1073/pnas.091415198
-
Giordano FJ, Gerber HP, Williams SP, VanBruggen N, Bunting S, Ruiz-Lozano P, Gu Y, Nath AK, Huang Y, Hickey R, Dalton N, Peterson KL, Ross J Jr, Chien KR, Ferrara N. A cardiac myocyte vascular endothelial growth factor paracrine pathway is required to maintain cardiac function. Proc Natl Acad Sci USA. 2001;98:5780-5785. (Pubitemid 32435719)
-
(2001)
Proceedings of the National Academy of Sciences of the United States of America
, vol.98
, Issue.10
, pp. 5780-5785
-
-
Giordano, F.J.1
Gerber, H.-P.2
Williams, S.-P.3
Vanbruggen, N.4
Bunting, S.5
Ruiz-Lozano, P.6
Gu, Y.7
Nath, A.K.8
Huang, Y.9
Hickey, R.10
Dalton, N.11
Peterson, K.L.12
Ross Jr., J.13
Chien, K.R.14
Ferrara, N.15
-
3
-
-
36049037185
-
Cardiomyocyte GATA4 functions as a stress-responsive regulator of angiogenesis in the murine heart
-
DOI 10.1172/JCI32573
-
Heineke J, Auger-Messier M, Xu J, Oka T, Sargent MA, York A, Klevitsky R, Vaikunth S, Duncan SA, Aronow BJ, Robbins J, Crombleholme TM, Molkentin JD. Cardiomyocyte GATA4 functions as a stress-responsive regulator of angiogenesis in the murine heart. J Clin Invest. 2007;117:3198-3210. (Pubitemid 350096978)
-
(2007)
Journal of Clinical Investigation
, vol.117
, Issue.11
, pp. 3198-3210
-
-
Heineke, J.1
Auger-Messier, M.2
Xu, J.3
Oka, T.4
Sargent, M.A.5
York, A.6
Klevitsky, R.7
Vaikunth, S.8
Duncan, S.A.9
Aronow, B.J.10
Robbins, J.11
Cromblehol, T.M.12
Molkentin, J.D.13
-
4
-
-
33947520124
-
P53-induced inhibition of Hif-1 causes cardiac dysfunction during pressure overload
-
DOI 10.1038/nature05602, PII NATURE05602
-
Sano M, Minamino T, Toko H, Miyauchi H, Orimo M, Qin Y, Akazawa H, Tateno K, Kayama Y, Harada M, Shimizu I, Asahara T, Hamada H, Tomita S, Molkentin JD, Zou Y, Komuro I. p53-induced inhibition of Hif-1 causes cardiac dysfunction during pressure overload. Nature. 2007; 446:444-448. (Pubitemid 46474597)
-
(2007)
Nature
, vol.446
, Issue.7134
, pp. 444-448
-
-
Sano, M.1
Minamino, T.2
Toko, H.3
Miyauchi, H.4
Orimo, M.5
Qin, Y.6
Akazawa, H.7
Tateno, K.8
Kayama, Y.9
Harada, M.10
Shimizu, I.11
Asahara, T.12
Hamada, H.13
Tomita, S.14
Molkentin, J.D.15
Zou, Y.16
Komuro, I.17
-
5
-
-
23644439061
-
Disruption of coordinated cardiac hypertrophy and angiogenesis contributes to the transition to heart failure
-
DOI 10.1172/JCI24682
-
Shiojima I, Sato K, Izumiya Y, Schiekofer S, Ito M, Liao R, Colucci WS, Walsh K. Disruption of coordinated cardiac hypertrophy and angiogenesis contributes to the transition to heart failure. J Clin Invest. 2005; 115:2108-2118. (Pubitemid 41134152)
-
(2005)
Journal of Clinical Investigation
, vol.115
, Issue.8
, pp. 2108-2118
-
-
Shiojima, I.1
Sato, K.2
Izumiya, Y.3
Schiekofer, S.4
Ito, M.5
Liao, R.6
Colucci, W.S.7
Walsh, K.8
-
6
-
-
0037465434
-
Progression from compensated hypertrophy to failure in the pressure-overloaded human: Heart structural deterioration and compensatory mechanisms
-
DOI 10.1161/01.CIR.0000051865.66123.B7
-
Hein S, Arnon E, Kostin S, Schonburg M, Elsasser A, Polyakova V, Bauer EP, Klovekorn WP, Schaper J. Progression from compensated hypertrophy to failure in the pressure-overloaded human heart: structural deterioration and compensatory mechanisms. Circulation. 2003;107: 984-991. (Pubitemid 36258721)
-
(2003)
Circulation
, vol.107
, Issue.7
, pp. 984-991
-
-
Hein, S.1
Arnon, E.2
Kostin, S.3
Schonburg, M.4
Elsasser, A.5
Polyakova, V.6
Bauer, E.P.7
Klovekorn, W.-P.8
Schaper, J.9
-
7
-
-
33646149385
-
Vascular endothelial growth factor blockade promotes the transition from compensatory cardiac hypertrophy to failure in response to pressure overload
-
DOI 10.1161/01.HYP.0000215207.54689.31, PII 0000426820060500000018
-
Izumiya Y, Shiojima I, Sato K, Sawyer DB, Colucci WS, Walsh K. Vascular endothelial growth factor blockade promotes the transition from compensatory cardiac hypertrophy to failure in response to pressure overload. Hypertension. 2006;47:887-893. (Pubitemid 44297560)
-
(2006)
Hypertension
, vol.47
, Issue.5
, pp. 887-893
-
-
Izumiya, Y.1
Shiojima, I.2
Sato, K.3
Sawyer, D.B.4
Colucci, W.S.5
Walsh, K.6
-
8
-
-
36048999385
-
Myocardial hypertrophy in the absence of external stimuli is induced by angiogenesis in mice
-
DOI 10.1172/JCI32024
-
Tirziu D, Chorianopoulos E, Moodie KL, Palac RT, Zhuang ZW, Tjwa M, Roncal C, Eriksson U, Fu Q, Elfenbein A, Hall AE, Carmeliet P, Moons L, Simons M. Myocardial hypertrophy in the absence of external stimuli is induced by angiogenesis in mice. J Clin Invest. 2007;117: 3188-3197. (Pubitemid 350096977)
-
(2007)
Journal of Clinical Investigation
, vol.117
, Issue.11
, pp. 3188-3197
-
-
Tirziu, D.1
Chorianopoulos, E.2
Moodie, K.L.3
Palac, R.T.4
Zhuang, Z.W.5
Tjwa, M.6
Roncal, C.7
Eriksson, U.8
Fu, Q.9
Elfenbein, A.10
Hall, A.E.11
Carmeliet, P.12
Moons, L.13
Simons, M.14
-
9
-
-
76649094893
-
Cardiomyocyte PDGFR-beta signaling is an essential component of the mouse cardiac response to load-induced stress
-
Chintalgattu V, Ai D, Langley RR, Zhang J, Bankson JA, Shih TL, Reddy AK, Coombes KR, Daher IN, Pati S, Patel SS, Pocius JS, Taffet GE, Buja LM, Entman ML, Khakoo AY. Cardiomyocyte PDGFR-beta signaling is an essential component of the mouse cardiac response to load-induced stress. J Clin Invest. 2010;120:472-484.
-
(2010)
J Clin Invest
, vol.120
, pp. 472-484
-
-
Chintalgattu, V.1
Ai, D.2
Langley, R.R.3
Zhang, J.4
Bankson, J.A.5
Shih, T.L.6
Reddy, A.K.7
Coombes, K.R.8
Daher, I.N.9
Pati, S.10
Patel, S.S.11
Pocius, J.S.12
Taffet, G.E.13
Buja, L.M.14
Entman, M.L.15
Khakoo, A.Y.16
-
10
-
-
4344563450
-
Endothelial cells promote cardiac myocyte survival and spatial reorganization: Implications for cardiac regeneration
-
DOI 10.1161/01.CIR.0000140667.37070.07
-
Narmoneva DA, Vukmirovic R, Davis ME, Kamm RD, Lee RT. Endothelial cells promote cardiac myocyte survival and spatial reorganization: implications for cardiac regeneration. Circulation. 2004;110:962-968. (Pubitemid 39136214)
-
(2004)
Circulation
, vol.110
, Issue.8
, pp. 962-968
-
-
Narmoneva, D.A.1
Vukmirovic, R.2
Davis, M.E.3
Kamm, R.D.4
Lee, R.T.5
-
11
-
-
34548132413
-
Role of neuregulin-1/ErbB signaling in cardiovascular physiology and disease: Implications for therapy of heart failure
-
DOI 10.1161/CIRCULATIONAHA.107.690487, PII 0000301720070821000013
-
Lemmens K, Doggen K, De Keulenaer GW. Role of neuregulin-1/ErbB signaling in cardiovascular physiology and disease: implications for therapy of heart failure. Circulation. 2007;116:954-960. (Pubitemid 47300920)
-
(2007)
Circulation
, vol.116
, Issue.8
, pp. 954-960
-
-
Lemmens, K.1
Doggen, K.2
De Keulenaer, G.W.3
-
12
-
-
34547935393
-
Impaired heart contractility in Apelin gene-deficient mice associated with aging and pressure overload
-
DOI 10.1161/CIRCRESAHA.107.158659, PII 0000301220070817000015
-
Kuba K, Zhang L, Imai Y, Arab S, Chen M, Maekawa Y, Leschnik M, Leibbrandt A, Markovic M, Schwaighofer J, Beetz N, Musialek R, Neely GG, Komnenovic V, Kolm U, Metzler B, Ricci R, Hara H, Meixner A, Nghiem M, Chen X, Dawood F, Wong KM, Sarao R, Cukerman E, Kimura A, Hein L, Thalhammer J, Liu PP, Penninger JM. Impaired heart contractility in Apelin gene-deficient mice associated with aging and pressure overload. Circ Res. 2007;101:e32-e42. (Pubitemid 47267711)
-
(2007)
Circulation Research
, vol.101
, Issue.4
-
-
Kuba, K.1
Zhang, L.2
Imai, Y.3
Arab, S.4
Chen, M.5
Maekawa, Y.6
Leschnik, M.7
Leibbrandt, A.8
Makovic, M.9
Schwaighofer, J.10
Beetz, N.11
Musialek, R.12
Neely, G.G.13
Komnenovic, V.14
Kolm, U.15
Metzler, B.16
Ricci, R.17
Hara, H.18
Meixner, A.19
Nghiem, M.20
Chen, X.21
Dawood, F.22
Wong, K.M.23
Sarao, R.24
Cukerman, E.25
Kimura, A.26
Hein, L.27
Thalhammer, J.28
Liu, P.P.29
Penninger, J.M.30
more..
-
13
-
-
2942590374
-
Nitric oxide and the enigma of cardiac hypertrophy
-
DOI 10.1002/bies.20049
-
Kempf T, Wollert KC. Nitric oxide and the enigma of cardiac hypertrophy. Bioessays. 2004;26:608-615. (Pubitemid 38758338)
-
(2004)
BioEssays
, vol.26
, Issue.6
, pp. 608-615
-
-
Kempf, T.1
Wollert, K.C.2
-
14
-
-
20944445197
-
Oxidant stress from nitric oxide synthase-3 uncoupling stimulates cardiac pathologic remodeling from chronic pressure load
-
DOI 10.1172/JCI200521968
-
Takimoto E, Champion HC, Li M, Ren S, Rodriguez ER, Tavazzi B, Lazzarino G, Paolocci N, Gabrielson KL, Wang Y, Kass DA. Oxidant stress from nitric oxide synthase-3 uncoupling stimulates cardiac pathologic remodeling from chronic pressure load. J Clin Invest. 2005; 115:1221-1231. (Pubitemid 40629040)
-
(2005)
Journal of Clinical Investigation
, vol.115
, Issue.5
, pp. 1221-1231
-
-
Takimoto, E.1
Champion, H.C.2
Li, M.3
Ren, S.4
Rodriguez, E.R.5
Tavazzi, B.6
Lazzarino, G.7
Paolocci, N.8
Gabrielson, K.L.9
Wang, Y.10
Kass, D.A.11
-
15
-
-
84857511879
-
The ATP-binding cassette transporter ATP-binding cassette transporter subfamily G member 2 protects against pressure overload-induced cardiac hypertrophy and heart failure by promoting angiogenesis and antioxidant response
-
Higashikuni Y, Sainz J, Nakamura K, Takaoka M, Enomoto S, Iwata H, Tanaka K, Sahara M, Hirata Y, Nagai R, Sata M. The ATP-binding cassette transporter ATP-binding cassette transporter subfamily G member 2 protects against pressure overload-induced cardiac hypertrophy and heart failure by promoting angiogenesis and antioxidant response. Arterioscler Thromb Vasc Biol. 2012;32:654-661.
-
(2012)
Arterioscler Thromb Vasc Biol
, vol.32
, pp. 654-661
-
-
Higashikuni, Y.1
Sainz, J.2
Nakamura, K.3
Takaoka, M.4
Enomoto, S.5
Iwata, H.6
Tanaka, K.7
Sahara, M.8
Hirata, Y.9
Nagai, R.10
Sata, M.11
-
16
-
-
78149282951
-
The ATP-binding cassette transporter BCRP1/ABCG2 plays a pivotal role in cardiac repair after myocardial infarction via modulation of microvascular endothelial cell survival and function
-
Higashikuni Y, Sainz J, Nakamura K, Takaoka M, Enomoto S, Iwata H, Sahara M, Tanaka K, Koibuchi N, Ito S, Kusuhara H, Sugiyama Y, Hirata Y, Nagai R, Sata M. The ATP-binding cassette transporter BCRP1/ABCG2 plays a pivotal role in cardiac repair after myocardial infarction via modulation of microvascular endothelial cell survival and function. Arterioscler Thromb Vasc Biol. 2010;30:2128-2135.
-
(2010)
Arterioscler Thromb Vasc Biol
, vol.30
, pp. 2128-2135
-
-
Higashikuni, Y.1
Sainz, J.2
Nakamura, K.3
Takaoka, M.4
Enomoto, S.5
Iwata, H.6
Sahara, M.7
Tanaka, K.8
Koibuchi, N.9
Ito, S.10
Kusuhara, H.11
Sugiyama, Y.12
Hirata, Y.13
Nagai, R.14
Sata, M.15
-
17
-
-
77951768113
-
Acute cardiovascular effects of apelin in humans: Potential role in patients with chronic heart failure
-
Japp AG, Cruden NL, Barnes G, van Gemeren N, Mathews J, Adamson J, Johnston NR, Denvir MA, Megson IL, Flapan AD, Newby DE. Acute cardiovascular effects of apelin in humans: potential role in patients with chronic heart failure. Circulation. 2010;121:1818-1827.
-
(2010)
Circulation
, vol.121
, pp. 1818-1827
-
-
Japp, A.G.1
Cruden, N.L.2
Barnes, G.3
Van Gemeren, N.4
Mathews, J.5
Adamson, J.6
Johnston, N.R.7
Denvir, M.A.8
Megson, I.L.9
Flapan, A.D.10
Newby, D.E.11
-
18
-
-
77952317892
-
A phase II, randomized, double-blind, multicenter, based on standard therapy, placebo-controlled study of the efficacy and safety of recombinant human neuregulin-1 in patients with chronic heart failure
-
Gao R, Zhang J, Cheng L, Wu X, Dong W, Yang X, Li T, Liu X, Xu Y, Li X, Zhou M. A phase II, randomized, double-blind, multicenter, based on standard therapy, placebo-controlled study of the efficacy and safety of recombinant human neuregulin-1 in patients with chronic heart failure. J Am Coll Cardiol. 2010;55:1907-1914.
-
(2010)
J Am Coll Cardiol
, vol.55
, pp. 1907-1914
-
-
Gao, R.1
Zhang, J.2
Cheng, L.3
Wu, X.4
Dong, W.5
Yang, X.6
Li, T.7
Liu, X.8
Xu, Y.9
Li, X.10
Zhou, M.11
|