Demethylation of the FOXP3 gene in human melanoma cells precludes the use of this epigenetic mark for quantification of Tregs in unseparated melanoma samples

International Journal of Cancer

Volumn 130, Issue 8, 2012, Pages 1960-1966

  Lucas, Sophie ^a   Van Baren, Nicolas ^a,b   De Smet, Charles ^a   Coulie, Pierre G ^a  

^a DE DUVE INSTITUTE   (Belgium)

^b LUDWIG INSTITUTE FOR CANCER RESEARCH   (Belgium)

Author keywords

cancer vaccine; FOXP3; human Treg marker; melanoma; regulatory T cells

Indexed keywords

CPG OLIGODEOXYNUCLEOTIDE; GENOMIC DNA; MESSENGER RNA; TRANSCRIPTION FACTOR FOXP3;

ARTICLE; COLORECTAL CARCINOMA; CONTROLLED STUDY; DEMETHYLATION; EPIGENETICS; HEMATOPOIETIC CELL; HUMAN; HUMAN CELL; IMMUNE RESPONSE; INTRON; LUNG CARCINOMA; MELANOMA; MELANOMA CELL; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; REGULATORY T LYMPHOCYTE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

BLOTTING, WESTERN; CELL LINE, TUMOR; COLORECTAL NEOPLASMS; CPG ISLANDS; DNA METHYLATION; EPIGENESIS, GENETIC; FEMALE; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IMMUNOHISTOCHEMISTRY; INTRONS; LUNG NEOPLASMS; MALE; MELANOMA; PHOSPHORYLATION; PROMOTER REGIONS, GENETIC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SMAD2 PROTEIN; T-LYMPHOCYTES; T-LYMPHOCYTES, REGULATORY; TRANSFORMING GROWTH FACTOR BETA; TUMOR MARKERS, BIOLOGICAL;

EID: 84857501047     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.26198     Document Type: Article

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