Lipid exchange mechanism of the cholesteryl ester transfer protein clarified by atomistic and coarse-grained simulations

PLoS Computational Biology

Volumn 8, Issue 1, 2012, Pages

  Koivuniemi, Artturi ^a   Vuorela, Timo ^a   Kovanen, Petri T ^b   Vattulainen, Ilpo ^a,c,d   Hyvönen, Marja T ^c,e  

^a TAMPERE UNIVERSITY OF TECHNOLOGY   (Finland)

^b WIHURI RESEARCH INSTITUTE   (Finland)

^c AALTO UNIVERSITY   (Finland)

^d UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

^e UNIVERSITY OF OULU   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; COARSE-GRAINED MODELING; DROPS; ESTERS; LIPOPROTEINS; MOLECULAR DYNAMICS;

ATOMISTICS; BLOOD PLASMA; CHOLESTERYL ESTER TRANSFER PROTEINS; CHOLESTERYL ESTERS; COARSE-GRAINED; EXCHANGE MECHANISM; LIPID DROPLETS; LIPID EXCHANGE; LIPOPROTEIN FRACTION; PROTEIN TRANSPORT;

PHOSPHOLIPIDS;

CHOLESTEROL ESTER TRANSFER PROTEIN; FAT DROPLET; HIGH DENSITY LIPOPROTEIN; PHOSPHOLIPID; TRYPTOPHAN; CHOLESTEROL ESTER;

ARTICLE; ATOMISTIC SIMULATION; CARBOXY TERMINAL SEQUENCE; COARSE GRAINED SIMULATION; HYDROPHOBICITY; LIPID TRANSPORT; MOLECULAR DYNAMICS; PROTEIN CONFORMATION; PROTEIN FUNCTION; PROTEIN LIPID INTERACTION; PROTEIN STRUCTURE; SIMULATION; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; COMPUTER SIMULATION; METABOLISM;

BINDING SITES; CHOLESTEROL ESTER TRANSFER PROTEINS; CHOLESTEROL ESTERS; COMPUTER SIMULATION; LIPOPROTEINS, HDL; MODELS, MOLECULAR; PROTEIN CONFORMATION;

EID: 84857482067     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1002299     Document Type: Article

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