Association of C-terminal region of phosphoglycerate mutase with glycolytic complex regulates energy production in cancer cells

Journal of Cellular Physiology

Volumn 227, Issue 6, 2012, Pages 2613-2621

  Kowalski, Wojciech ^a   Nocon, Dominika ^a   Gamian, Andrzej ^b,c   Kolodziej, Jerzy ^b   Rakus, Dariusz ^a  

^a UNIVERSITY OF WROC AW   (Poland)

^b WROCLAW MEDICAL UNIVERSITY   (Poland)

^c INSTITUTE OF IMMUNOLOGY AND EXPERIMENTAL THERAPY   (Poland)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; FRUCTOSE BISPHOSPHATE ALDOLASE; GLUCOSE; LACTIC ACID; PHOSPHOGLYCERATE MUTASE; PYRUVATE KINASE;

ARTICLE; CANCER CELL; CELL ENERGY; CELL PROLIFERATION; CONTROLLED STUDY; ENERGY YIELD; ENZYME METABOLISM; ENZYME SYNTHESIS; GLYCOLYSIS; HUMAN; HUMAN CELL; IN VIVO STUDY; PRIORITY JOURNAL;

ACTIVE TRANSPORT, CELL NUCLEUS; ADENOSINE TRIPHOSPHATE; ANIMALS; ANTINEOPLASTIC AGENTS; CARCINOMA, NON-SMALL-CELL LUNG; CARCINOMA, SQUAMOUS CELL; CELL LINE, TUMOR; CELL PROLIFERATION; ENERGY METABOLISM; FRUCTOSE-BISPHOSPHATE ALDOLASE; GLUCOSE; GLYCOLYSIS; HUMANS; LACTIC ACID; LUNG NEOPLASMS; MICE; MULTIENZYME COMPLEXES; PEPTIDES; PHOSPHOGLYCERATE MUTASE; PROTEIN STRUCTURE, TERTIARY; PYRUVATE KINASE;

EID: 84857466328     PISSN: 00219541     EISSN: 10974652     Source Type: Journal    
DOI: 10.1002/jcp.22998     Document Type: Article

References (29)

1. Bergmeyer HU, Gawehn K, Grassl M. 1974. Methods of enzymatic analysis. In: Bergmeyer HU, editor. Berlag Chemie Weinhein, Vol. 1. New York: Academic Press. pp 425-522.
2. Costa Leite T, Da Silva D, Guimarães Coelho R, Zancan P, Sola-Penna M. 2007. Lactate favours the dissociation of skeletal muscle 6-phosphofructo-1-kinase tetramers down-regulating the enzyme and muscle glycolysis. Biochem J 408:123-130.
3. David CJ, Chen M, Assanah M, Canoll P, Manley JL. 2010. HnRNP proteins controlled by c-Myc deregulate pyruvate kinase mRNA splicing in cancer. Nature 463:364-368.
4. Engel M, Mazurek S, Eigenbrodt E, Welter C. 2004. Phosphoglycerate mutase-derived polypeptide inhibits glycolytic flux and induces cell growth arrest in tumor cell lines. J Biol Chem 279:35803-35812.
5. Fantin VR, St-Pierre J, Leder P. 2006. Attenuation of LDH-A expression uncovers a link between glycolysis, mitochondrial physiology, and tumor maintenance. Cancer Cell 9:425-434.
6. Fillinger S, Boschi-Muller S, Azza S, Dervyn E, Branlant G, Aymerich S. 2000. Two glyceraldehyde-3-phosphate dehydrogenases with opposite physiological roles in a nonphotosynthetic bacterium. J Biol Chem 275:14031-14037.
7. Fujii H, Miwa S. 1983. Pyruvate kinase. In: Bergmeyer HU, editor. Methods of enzymatic analysis, Berlag Chemie Weinhein. New York: Academic Press. pp 496-502.
8. Gizak A, Dzugaj A. 2003. FBPase is in the nuclei of cardiomyocytes. FEBS Lett 539:51-55.
9. Goding JW. 1976. Conjugation of antibodies with fluorochromes: Modifications to the standard methods. J Immunol Methods 13:215-226.
10. Jares-Erijman EA, Jovin TM. 2003. FRET imaging. Nat Biotechnol 21:1387-1395.
11. Knull HR. 1980. Compartmentation of glycolytic enzymes in nerve endings as determined by glutaraldehyde fixation. J Biol Chem 255:6439-6444.
12. Kondoh H, Lleonart ME, Gil J, Wang J, Degan P, Peters G, Martinez D, Carnero A, Beach D. 2005. Glycolytic enzymes can modulate cellular life span. Cancer Res 65:177-185.
13. Kowalski W, Gizak A, Rakus D. 2009. Phosphoglycerate mutase in mammalian striated muscles: Subcellular localization and binding partners. FEBS Lett 583:1841-1845.
14. Kraft T, Hornemann T, Stolz M, Nier V, Wallimann T. 2000. Coupling of creatine kinase to glycolytic enzymes at the sarcomeric I-band of skeletal muscle: A biochemical study in situ. J Muscle Res Cell Motil 21:691-703.
15. Mayor S, Bilgrami S. 2007. Fretting about FRET in cell and structural biology. In: Zuk D, editor. Evaluating techniques in biochemical research. Cambridge, MA: Cell Press. pp 43-49.
16. Mazurek S, Hugo F, Failing K, Eigenbrodt E. 1996. Studies on associations of glycolytic and glutaminolytic enzymes in MCF-7 cells: Role of P36. J Cell Physiol 167:238-250.
17. Mazurek S, Grimm H, Wilker S, Leib S, Eigenbrodt E. 1998. Metabolic characteristics of different malignant cancer cell lines. Anticancer Res 18:3275-3282.
18. Mazurek S, Eigenbrodt E, Failing K, Steinberg P. 1999. Alterations in the glycolytic and glutaminolytic pathways after malignant transformation of rat liver oval cells. J Cell Physiol 181:136-146.
19. Mazurek S, Zwerschke W, Jansen-Dürr P, Eigenbrodt E. 2001. Effects of the human papilloma virus HPV-16 E7 oncoprotein on glycolysis and glutaminolysis: Role of pyruvate kinase type M2 and the glycolytic-enzyme complex. Biochem J 356:247-256.
20. Mazurek S, Grimm H, Boschek CB, Vaupel P, Eigenbrodt E. 2002. Pyruvate kinase type M2: A crossroad in the tumor metabolome. Br J Nutr 87:23-29.
21. Mazurek S, Boschek CB, Hugo F, Eigenbrodt E. 2005. Pyruvate kinase type M2 and its role in tumor growth and spreading. Semin Cancer Biol 15:300-308.
22. Mazurek S. 2011. Pyruvate kinase type M2: A key regulator of the metabolic budget system in tumor cells. Int J Biochem Cell Biol 43:969-980.
23. Merkle S, Pretsch W. 1989. Characterization of triosephosphate isomerase mutants with reduced enzyme activity in Mus musculus. Genetics 123:837-844.
24. Noll F. 1984. L-(+)-Lactate. In: Bergmeyer HU, editor. Methods of enzymatic analysis, Vol. 6. Berlag Chemie Weinhein. New York: Academic Press. pp 582-587.
25. Pancholi V, Fischetti VA. 1998. Alpha-enolase a novel strong plasmin(ogen) binding protein on the surface of pathogenic streptococci. J Biol Chem 273:14503-14515.
26. Rakus D, Mamczur P, Gizak A, Dus D, Dzugaj A. 2003. Colocalization of muscle FBPase and muscle aldolase on both sides of the Z-line. Biochem Biophys Res Commun 311:294-299.
27. Sygusch J, Beaudry D. 1984. Catalytic activity of rabbit skeletal muscle aldolase in the crystalline state. J Biol Chem 259:10222-10227.
28. Walenta S, Mueller-Klieser WF. 2004. Lactate: Mirror and motor of tumor malignancy. Semin Radiat Oncol 14:267-274.
29. Walter RA, Nairn J, Duncan D, Price NC, Kelly SM, Rigden DJ, Fothergill-Gilmore LA. 1999. The role of the C-terminal region in phosphoglycerate mutase. Biochem J 337:89-95.