General oxidative stress during doxorubicin-induced cardiotoxicity in rats: Absence of cardioprotection and low antioxidant efficiency of alpha-lipoic acid

Biochimie

Volumn 94, Issue 4, 2012, Pages 932-939

  Ghibu, Steliana ^a   Delemasure, Stéphanie ^b   Richard, Carole ^b   Guilland, Jean Claude ^b   Martin, Laurent ^c   Gambert, Ségolne ^c   Rochette, Luc ^b   Vergely, Catherine ^b  

^a IULIU HATIEGANU UNIVERSITY OF MEDICINE AND PHARMACY   (Romania)

^b UNIVERSITÉ DE BOURGOGNE   (France)

^c DIJON UNIVERSITY HOSPITAL   (France)

Author keywords

Alpha lipoic acid; Anthracyclines; Cardioprotection; Doxorubicin; Oxidative stress; Rat hearts

Indexed keywords

ASCORBIC ACID; DOXORUBICIN; HYDROETHIDINE; HYDROPEROXIDE; MALONALDEHYDE; THIOBARBITURIC ACID REACTIVE SUBSTANCE; THIOCTIC ACID; THIOGAMMA 600; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; ARTICLE; ASCITES; BODY WEIGHT; CARDIOTOXICITY; CONTROLLED STUDY; ELECTRON SPIN RESONANCE; FLUORESCENCE ANALYSIS; HEART CATHETERIZATION; HEART FUNCTION; HEART MUSCLE CONTRACTILITY; HEART PROTECTION; HEART VENTRICLE HYPERTROPHY; HEMATOCRIT; HISTOPATHOLOGY; IN VIVO STUDY; LIPID PEROXIDATION; MALE; NONHUMAN; OXIDATIVE STRESS; PROTEIN BLOOD LEVEL; RAT;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; ANTIOXIDANTS; ASCITIC FLUID; ASCORBIC ACID; BODY WEIGHT; CARDIOTONIC AGENTS; CARDIOTOXINS; DOXORUBICIN; EATING; HEART; HEART DISEASES; HEMATOCRIT; HYDROGEN PEROXIDE; LIVER; MALE; MYOCARDIUM; ORGAN SIZE; OXIDATIVE STRESS; RATS; RATS, WISTAR; SUPEROXIDES; THIOBARBITURIC ACID REACTIVE SUBSTANCES; THIOCTIC ACID;

RATTUS; RATTUS NORVEGICUS;

EID: 84857447758     PISSN: 03009084     EISSN: 61831638     Source Type: Journal    
DOI: 10.1016/j.biochi.2011.02.015     Document Type: Article

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