Ethanolic extract of Crinum asiaticum attenuates hyperglycemia-mediated oxidative stress and protects hepatocytes in alloxan induced experimental diabetic rats

Journal of King Saud University - Science

Volumn 24, Issue 2, 2012, Pages 171-177

  Indradevi, S ^a   Ilavenil, S ^a   Kaleeswaran, B ^a   Srigopalram, S ^b   Ravikumar, S ^a  

^a PRIST UNIVERSITY   (India)

^b KONGUNADU ARTS AND SCIENCE COLLEGE   (India)

Author keywords

Antioxidant; Crinum asiaticum; Diabetes mellitus; Hepatic tissues; Oxidative stress

Indexed keywords

EID: 84857445259     PISSN: 10183647     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jksus.2010.12.007     Document Type: Article

References (36)

1. Aebi H. Catalase in vitro. Methods Enzymol. 1983, 105:121-126.
2. Albano E. Oxidative mechanisms in the pathogenesis of alcoholic liver disease. Mol. Aspects Med. 2008, 29:9-16.
3. Ananthan R., Latha M., Pari L., Baskar C., Narmatha V. Modulatory effects of Gymnema montanum leaf extract on alloxan induced oxidative stress in Wistar rats. Nutrition 2004, 20:280-285.
4. Arvind K., Pradeep R., Deepa R., Mohan V. Diabetes and coronary artery disease. Indian J. Med. Res. 2002, 116:163-176.
5. Bandyopadhyay Uday, Das Dipak, Banerjee Ranajit K. Reactive oxygen species: oxidative damage and pathogenesis. Curr. Sci. 1999, 5:658.
6. Baydas G., Canatan H., Turkoglu A. Comparative analysis of the protective effects of melatonin and vitamin E on streptozocin-induced diabetes mellitus. J. Pineal Res. 2002, 32:225-230.
7. Berton T.R., Conti C.J., Mitchell D.L., Aldaz C.M., Lubet R.A., Fischer S.M. The effect of vitamin E acetate on ultraviolet induced mouse skin carcinogenesis. Mol. Carcinog. 1998, 23:175-184.
8. Bopanna K.N., Kannan J., Gadgil S., Balaraman R., Rathod S.P. Antidiabetic and antihyperglycemic effects of Neem seed kernel powder alloxan diabetic rabbits. Indian J. Pharmacol. 1997, 29:162-167.
9. Chakravarthy B.K., Gupta S., Gambhir S.S., Gode K.D. Pancreatic beta cell regeneration a novel antidiabetic mechanism of Petercarpus marsupium. Indian J. Pharmacol. 1980, 12:123-128.
10. Chang M.W., Johnson M.A. Effect of garlic on carbohydrate metabolism and lipid synthesis in rats. J. Nutr. 1980, 110:931-936.
11. Cho S.Y., Park J.Y., Park E.M., Choi M.S., Lee M.K., Jeon S.M., Jang M.K., Kim M.J., Park Y.B. Alternation of hepatic antioxidant enzyme activities and lipid profile in streptozotocin-induced diabetic rats by supplementation of dandelion water extract. Clin. Chim. Acta 2002, 317:109-117.
12. Chopra R.N., Nair S.L., Chopra J.C. Glossary of Indian Medicinal Plants 1981, CSIR Publication, New Delhi, p. 50.
13. Collier E., Watkinson A., Cleland C.F., Roth J. Partial purification and characterization of insulin like material from spinach and Lemna gibba G3. J. Boil. Chem. 1987, 262:6237-6238.
14. Davis J. Inactivation of the antibiotics and the dissemination of resistance genes. Science 1994, 264:375-382.
15. Duke, J.A., Ayensu, E.S., 1985. Medicinal Plants of China, vol. 1. Reference Publications Inc.
16. Ellman GL. Tissue sulphydryl groups. Arch. Biochem. 1959, 70-77.
17. Evans J.L., Goldfine I.D., Maddux B.A., Grodsky G.M. Oxidative stress and stress-activated signaling pathways: a unifying hypothesis of type 2 diabetes. Endocr. Rev. 2002, 23:599-622.
18. Goeltenboth, F., Holdworth, D.K., Sakulas, H., Thredgold, H., Woodley, E., Yauieb, A., 1991. In: Woodly, E. (Ed.), Medical Plants of Papua New Guinea. Wau Ecology Institute, F.&T. Mullerbader, Germany.
19. Grover J.K., Vats V., Rathi S.S. Anti-hyperglycemic effect of Eugenia jambolana and Tinospora cordifolia in experimental diabetes and their effect on key metabolic enzymes involved in carbohydrate metabolism. J. Ethnopharmacol. 2000, 73:461-470.
20. Hünkar T., Aktan F., Ceylan A., Karasu C. Antioxidants in Diabetes-induced Complications (ADIC) Study Group, Effects of cod liver oil on tissue antioxidant pathways in normal and streptozotocin-diabetic rats. Cell Biochem. Funct. 2002, 20:297-302.
21. Ilavenil S., Kaleeswaran B., Ravikumar S. Evaluation of antibacterial activity and phytochemical analysis of crinum asiaticum. Int. J. Curr. Res. 2010, 1:35-40.
22. Kakkar P., Das B., Viswanathan P.N. A modified spectrophotometric assay of superoxide dismutase. Indian J. Biochem. Biophys. 1984, 21:130-132.
23. Kiritikar, K.R., Basu, B.D., 1999. Indian Medicinal Plants, second ed. International Book Distributors, Dehradun, pp. 205-206.
24. Kleiner D.E., Brunt E.M., Van Natta M., Behling C., Contos M.J., Cummings O.W., Ferrell L.D., Liu Y.C., Torbenson M.S., Unalp-Arida A., Yeh M., McCullough A.J., Sanyal A.J. Nonalcoholic steatohepatitis clinical research network, design and validation of a histological scoring system for nonalcoholic fatty liver disease. Hepatology 2005, 41:1313-1321.
25. Kumar G.P., Kumar S.D., Subremanian P.S. Anti-diabetic activity of fruits of Terminalia chebula on streptozotocin induced diabetic rats. J. Health Sci. 2006, 52:283-291.
26. Kume E., Fujimura H., Matsuki N., Ito M., Aruga C., Toriumi W., Kitamura K., Doi K. Hepatic changes in the acute phase of streptozotocin (SZ)-induced diabetes in mice. Exp. Toxicol. Pathol. 2004, 55:467-480.
27. Luzi P., Rafi M.A., Victoria T., Baskin G.B., Wenger D.A. Characterization of the rhesus monkey galactocerebrosidase (GALC) cDNA and gene and identification of the mutation causing globoid cell leukodystrophy (Krabbe disease) in this primate. Genomics 1997, 42:319-324.
28. Prakasam A., Sethupathy S., Pugalendi K.V. Hypolipidemic effect of Casearia esculenta root extracts in streptozotocin-induced diabetic rats. Pharmazie 2003, 58:828-832.
29. Shao J., Qiao L., Janssen R.C., Pagliassotti M., Friedman J.E. Chronic hyperglycemia enhances PEPCK gene expression and hepatocellular glucose production via elevated liver activating protein/liver inhibitory protein ratio. Diabetes 2005, 54:976-984.
30. Sinha AK. Colorimetric assay of catalase. Anal. Biochem. 1982, 47:389-394.
31. Stadler K., Jenei V., von Bölcsházy G., Somogyi A., Jakus J. Increased nitric oxide levels as an early sign of premature aging in diabetes. Free Radic. Biol. Med. 2003, 35:1240-1251.
32. Sumana G., Suryawanshi S.A. Effect of Vinca rosea extracts in treatments of alloxan diabetes in male albino rats. Indian J. Expt. Biol. 2001, 39:748-759.
33. Szkudelski T. The mechanism of alloxan and streptozotocin action in B-cells of the rat pancreas. Physiol. Res. 2001, 50:536.
34. Tanquilut N.C., Tanquilut M.A.C., Torres E.B., Rosario J.C., Reyes B.A.S. Hypoglycemic effect of Lagerstroemia speciosa (L.) Pers. on alloxan-induced diabetic mice. J. Med. Plants Res. 2009, 3(12):1066-1071.
35. Wiart, C., 2000. Medicinal Plants of Southeast Asia. Pelanduk Publications, (M) Sdn. Bhd.
36. Youssef W., McCullough A.J. Diabetes mellitus, obesity, and hepatic steatosis. Semin. Gastrointest. Dis. 2002, 13:17-30.