Tissue engineering of cartilage using a mechanobioreactor exerting simultaneous mechanical shear and compression to simulate the rolling action of articular joints

Biotechnology and Bioengineering

Volumn 109, Issue 4, 2012, Pages 1060-1073

  Shahin, Kifah ^a   Doran, Pauline M ^b  

^a UNIVERSITY OF NEW SOUTH WALES   (Australia)

^b SWINBURNE UNIVERSITY OF TECHNOLOGY   (Australia)

Author keywords

Cartilage; Compression; Mechanical shear; Mechanobioreactor; Scaffold; Tissue engineering

Indexed keywords

ARTICULAR JOINTS; AXIAL COMPRESSIVE STRAIN; CELL DENSITY; COMPRESSIVE LOADING; COMPRESSIVE STRAIN; CONTROL CULTURES; DYNAMIC MECHANICAL; GLYCOSAMINOGLYCANS; HUMAN CHONDROCYTES; LOADING REGIMES; MECHANICAL SHEAR; MECHANICAL STIMULATION; MECHANICAL TREATMENTS; MECHANOBIOREACTOR; MIXED FLUIDS; PERFUSION BIOREACTOR; PERFUSION CULTURES; POLYGLYCOLIC ACIDS; RECIRCULATIONS; SHEAR FORCE; STRUCTURAL COMPONENT; TISSUE ENGINEERED CARTILAGE; TYPE II;

BOTTLES; CARTILAGE; CELL CULTURE; COLLAGEN; COMPACTION; DYNAMICS; JOINTS (ANATOMY); LOADING; QUALITY CONTROL; SCAFFOLDS; SHEAR FLOW; TISSUE; TISSUE ENGINEERING;

SCAFFOLDS (BIOLOGY);

ALGINIC ACID; COLLAGEN TYPE 2; GLYCOSAMINOGLYCAN; POLYGLYCOLIC ACID;

ARTICLE; ARTICULAR CARTILAGE; BIOREACTOR; CARTILAGE CELL; CELL DENSITY; COMPRESSION; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN TISSUE; MECHANICAL SHEAR; MECHANOBIOREACTOR; PHYSICAL PARAMETERS; SIMULATION; TISSUE ENGINEERING;

ALGINATES; BATCH CELL CULTURE TECHNIQUES; BIOMECHANICS; BIOREACTORS; CELLS, CULTURED; CHONDROCYTES; COLLAGEN TYPE II; COMPRESSIVE STRENGTH; EQUIPMENT DESIGN; GLUCURONIC ACID; GLYCOSAMINOGLYCANS; GROWTH PLATE; HEXURONIC ACIDS; HUMANS; JOINTS; PERFUSION; POLYGLYCOLIC ACID; PRESSURE; SHEAR STRENGTH; STRESS, MECHANICAL; TISSUE ENGINEERING; TISSUE SCAFFOLDS; WEIGHT-BEARING;

EID: 84857444475     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.24372     Document Type: Article

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