Anomalous Brownian motion discloses viscoelasticity in the ear's mechanoelectrical-transduction apparatus

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 8, 2012, Pages 2896-2901

  Kozlov, Andrei S ^a   Andor Ardó, Daniel ^a   Hudspeth, A J ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

Author keywords

Auditory system; Hair cell; Interferometry; Vestibular system

Indexed keywords

BIOPOLYMER;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BROWNIAN MOTION; CONTROLLED STUDY; ENERGY; HAIR CELL; HEARING; MECHANOTRANSDUCTION; MOTION; NOISE; NONHUMAN; PRIORITY JOURNAL; SACCULUS; SCANNING ELECTRON MICROSCOPY; THEORY; VISCOELASTICITY; YOUNG MODULUS;

ANIMALS; ANURA; BIOMECHANICS; DIFFUSION; EAR; ELASTIC MODULUS; ELASTICITY; HAIR CELLS, AUDITORY; ION CHANNEL GATING; LINEAR MODELS; MECHANOTRANSDUCTION, CELLULAR; MODELS, BIOLOGICAL; MOTION; SACCULE AND UTRICLE; TEMPERATURE; VISCOSITY;

EID: 84857412320     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1121389109     Document Type: Article

References (32)

1. Austin RH, Beeson KW, Eisenstein L, Frauenfelder H, Gunsalus IC (1975) Dynamics of ligand binding to myoglobin. Biochemistry 14:5355-5373.
2. Henzler-Wildman K, Kern D (2007) Dynamic personalities of proteins. Nature 450:964-972. (Pubitemid 350273626)
3. Yang H, et al. (2003) Protein conformational dynamics probed by single-molecule electron transfer. Science 302:262-266. (Pubitemid 37248752)
4. Min W, Luo G, Cherayil BJ, Kou SC, Xie XS (2005) Observation of a power-law memory kernel for fluctuations within a single protein molecule. Phys Rev Lett 94:198302-1-198302-4.
5. De Vries HL (1948) Brownian movement and hearing. Physica 14:48-60.
6. Narins PM, Lewis ER (1984) The vertebrate ear as an exquisite seismic sensor. J Acoust Soc Am 76:1384-1387. (Pubitemid 15192683)
7. Jaramillo F, Wiesenfeld K (1998) Mechanoelectrical transduction assisted by Brownian motion: a role for noise in auditory system. Nature Neurosci 1:384-388.
8. Hudspeth AJ (1989) Mechanoelectrical transduction by hair cells of the bullfrog's sacculus. Prog Brain Res 80:129-135.
9. Pickles JO (1993) A model for the mechanics of stereociliar bundle on acousticolateral hair cells. Hear Res 68:159-172.
10. Grigolini P, Rocco A,West BJ (1999) Fractional calculus as a macroscopic manifestation of randomness. Phys Rev E 59:2603-2613. (Pubitemid 129306019)
11. Mason TG, Weitz DA (1995) Optical measurements of frequency-dependent linear viscoelastic moduli of complex fluids. Phys Rev Lett 74:1250-1253.
12. Martin P, Hudspeth AJ, Jülicher F (2001) Comparison of a hair bundle's spontaneous oscillations with its response to mechanical stimulation reveals the underlying active process. Proc Natl Acad Sci USA 98:14380-14385. (Pubitemid 33121400)
13. Lukić B, et al. (2005) Direct observation of nondiffusive motion of a Brownian particle. Phys Rev Lett 95:160601-1-160601-4.
14. Mandelbrot BB, Ness JWV (1968) Fractional Brownian motions, fractional noises and applications. SIAM Rev 10:422-437.
15. Kou SC, Xie XS (2004) Generalized Langevin equation with fractional Gaussian noise: subdiffusion within a single protein molecule. Phys Rev Lett 93:180603-1-180603-4.
16. Debnath P, Win M, Xie XS, Cherayil BJ (2005) Multiple time scale dynamics of distance fluctuations in a semiflexible polymer: a one-dimensional generalized Langevin equation treatment. J Chem Phys 123:204903-1-204903-1.
17. Kazmierczak P, et al. (2007) Cadherin 23 and protocadherin 15 interact to form tip-link filaments in sensory hair cells. Nature 449:87-91. (Pubitemid 47373771)
18. Nadrowski B, Martin P, Jülicher F (2004) Active hair-bundle motility harnesses noise to operate near an optimum of mechanosensitivity. Proc Natl Acad Sci USA 101:12195-12200. (Pubitemid 39145419)
19. Denk W, Keolian RM, Webb WW (1992) Mechanical response of frog saccular hair bundles to the aminoglycoside block of mechanoelectrical transduction. J Neurophysiol 68:927-932.
20. Kozlov AS, Risler T, Hudspeth AJ (2007) Coherent motion of stereocilia assures the concerted gating of hair-cell transduction channels. Nature Neurosci 10:87-92. (Pubitemid 46026531)
21. Denk W, Webb WW, Hudspeth AJ (1989) Mechanical properties of sensory hair bundles are reflected in their Brownian motion measured with a laser differential interferometer. Proc Natl Acad Sci USA 86:5371-5375. (Pubitemid 19185552)
22. Bashtanov ME, Goodyear RJ, Richardson GP, Russell IJ (2004) The mechanical properties of chick (Gallus domesticus) sensory hair bundles: relative contributions of structures sensitive to calcium chelation and subtilisin treatment. J Physiol 559:287-299. (Pubitemid 39206969)
23. Gemant A (1936) A method of analyzing experimental results obtained from elastoviscousbodies. Physics 7:311-317.
24. Sotomayor M, Weihofen WA, Gaudet R, Corey DP (2010) Structural determinants of cadherin-23 function in hearing and deafness. Neuron 66:85-100.
25. 2+ changes the force sensitivity of the hair-cell transduction channel. Biophys J 90:124-139.
26. Bozovic D, Hudspeth AJ (2003) Hair-bundle movements elicited by transepithelial electrical stimulation of hair cells in the bullfrog's sacculus. Proc Natl Acad Sci USA 100:958-963. (Pubitemid 36183937)
27. Martin P, Bozovic D, Choe Y, Hudspeth AJ (2003) Spontaneous oscillation by hair bundles of the bullfrog's sacculus. J Neurosci 23:4533-4548. (Pubitemid 36706184)
28. Sul B, Iwasa KH (2009) Amplifying effect of a release mechanism for fast adaptation in the hair bundle. J Acoust Soc Am 126:4-6.
29. Kozlov AS, Baumgart J, Risler T, Versteegh CPC, Hudspeth AJ (2011) Forces between clustered stereocilia minimize friction in the ear on a subnanometre scale. Nature 474:376-379.
30. van Netten SM, Dinklo T, Marcotti W, Kros CJ (2003) Channel gating forces govern accuracy of mechano-electrical transduction in hair cells. Proc Natl Acad Sci USA 100:15510-15515. (Pubitemid 38021020)
31. Denk W, Webb WW (1990) Optical measurement of picometer displacements of transparent microscopic objects. Appl Optics 29:2382-2391.
32. Percival DB, Walden AT (1993) Spectral Analysis for Physical Applications: Multitaper and Conventional Univariate Techniques (Cambridge University Press, Cambridge United Kingdom).