The effects of apolipoprotein F deficiency on high density lipoprotein cholesterol metabolism in mice

PLoS ONE

Volumn 7, Issue 2, 2012, Pages

  Lagor, William R ^a   Fields, David W ^a   Khetarpal, Sumeet A ^a   Kumaravel, Arthi ^a   Lin, Wen ^a   Weintraub, Nathaniel ^a   Wu, Kaijin ^b   Hamm Alvarez, Sarah F ^b   Drazul Schrader, Denise ^c   de la Llera Moya, Margarita ^c   Rothblat, George H ^c   Rader, Daniel J ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^c CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ABC TRANSPORTER A1; APOLIPOPROTEIN; APOLIPOPROTEIN F; CHOLESTEROL ESTER; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; BETA GALACTOSIDASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CHOLESTEROL BLOOD LEVEL; CHOLESTEROL LIVER LEVEL; CHOLESTEROL METABOLISM; CHOLESTEROL TRANSPORT; CONTROLLED STUDY; FEMALE; LIPID COMPOSITION; MACROPHAGE; MALE; MOLECULAR SIZE; MOUSE; NONHUMAN; PROTEIN ANALYSIS; SEX DIFFERENCE; ANIMAL; BLOOD; CELL STRAIN HEK293; FEEDING BEHAVIOR; GLYCOSYLATION; HUMAN; LIPID DIET; METABOLISM; MOLECULAR WEIGHT; MOUSE MUTANT; PROTEIN PROCESSING; REPORTER GENE; SECRETION; STAINING; TRANSPORT AT THE CELLULAR LEVEL;

ANIMALS; APOLIPOPROTEINS; BETA-GALACTOSIDASE; BIOLOGICAL TRANSPORT; CHOLESTEROL, HDL; DIET, HIGH-FAT; FEEDING BEHAVIOR; FEMALE; GENES, REPORTER; GLYCOSYLATION; HEK293 CELLS; HUMANS; MALE; MICE; MICE, KNOCKOUT; MOLECULAR WEIGHT; PROTEIN PROCESSING, POST-TRANSLATIONAL; STAINING AND LABELING;

EID: 84857397079     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0031616     Document Type: Article

References (47)

1. Olofsson SO, McConathy WJ, Alaupovic P, (1978) Isolation and partial characterization of a new acidic apolipoprotein (apolipoprotein F) from high density lipoproteins of human plasma. Biochemistry 17: 1032-1036.
2. Koren E, McConathy WJ, Alaupovic P, (1982) Isolation and characterization of simple and complex lipoproteins containing apolipoprotein F from human plasma. Biochemistry 21: 5347-5351.
3. Segrest JP, Jones MK, De Loof H, Brouillette CG, Venkatachalapathi YV, et al. (1992) The amphipathic helix in the exchangeable apolipoproteins: a review of secondary structure and function. J Lipid Res 33: 141-166.
4. Jones MK, Anantharamaiah GM, Segrest JP, (1992) Computer programs to identify and classify amphipathic alpha helical domains. J Lipid Res 33: 287-296.
5. Day JR, Albers JJ, Gilbert TL, Whitmore TE, McConathy WJ, et al. (1994) Purification and molecular cloning of human apolipoprotein F. Biochem Biophys Res Commun 203: 1146-1151.
6. Nishide T, Tollefson JH, Albers JJ, (1989) Inhibition of lipid transfer by a unique high density lipoprotein subclass containing an inhibitor protein. J Lipid Res 30: 149-158.
7. Morton RE, Steinbrunner JV, (1993) Determination of lipid transfer inhibitor protein activity in human lipoprotein-deficient plasma. Arterioscler Thromb 13: 1843-1851.
8. Morton RE, Greene DJ, (1994) Regulation of lipid transfer between lipoproteins by an endogenous plasma protein: selective inhibition among lipoprotein classes. J Lipid Res 35: 836-847.
9. Wang X, Driscoll DM, Morton RE, (1999) Molecular cloning and expression of lipid transfer inhibitor protein reveals its identity with apolipoprotein F. J Biol Chem 274: 1814-1820.
10. Serdyuk AP, Morton RE, (1999) Lipid transfer inhibitor protein defines the participation of lipoproteins in lipid transfer reactions: CETP has no preference for cholesteryl esters in HDL versus LDL. Arterioscler Thromb Vasc Biol 19: 718-726.
11. Paromov VM, Morton RE, (2003) Lipid transfer inhibitor protein defines the participation of high density lipoprotein subfractions in lipid transfer reactions mediated by cholesterol ester transfer protein (CETP). J Biol Chem 278: 40859-40866.
12. Morton RE, Greene DJ, (2003) CETP and lipid transfer inhibitor protein are uniquely affected by the negative charge density of the lipid and protein domains of LDL. J Lipid Res 44: 2287-2296.
13. He Y, Greene DJ, Kinter M, Morton RE, (2008) Control of cholesteryl ester transfer protein activity by sequestration of lipid transfer inhibitor protein in an inactive complex. J Lipid Res 49: 1529-1537.
14. Lagor WR, Brown RJ, Toh SA, Millar JS, Fuki IV, et al. (2009) Overexpression of apolipoprotein F reduces HDL cholesterol levels in vivo. Arterioscler Thromb Vasc Biol 29: 40-46.
15. Bashtovyy D, Jones MK, Anantharamaiah GM, Segrest JP, (2011) Sequence conservation of apolipoprotein A-I affords novel insights into HDL structure-function. J Lipid Res 52: 435-450.
16. Leong JS, Jantzen SG, von Schalburg KR, Cooper GA, Messmer AM, et al. (2010) Salmo salar and Esox lucius full-length cDNA sequences reveal changes in evolutionary pressures on a post-tetraploidization genome. BMC Genomics 11: 279.
17. Izem L, Morton RE, (2009) Molecular cloning of hamster lipid transfer inhibitor protein (apolipoprotein F) and regulation of its expression by hyperlipidemia. J Lipid Res 50: 676-684.
18. Hogarth CA, Roy A, Ebert DL, (2003) Genomic evidence for the absence of a functional cholesteryl ester transfer protein gene in mice and rats. Comp Biochem Physiol B Biochem Mol Biol 135: 219-229.
19. Guyard-Dangremont V, Desrumaux C, Gambert P, Lallemant C, Lagrost L, (1998) Phospholipid and cholesteryl ester transfer activities in plasma from 14 vertebrate species. Relation to atherogenesis susceptibility. Comp Biochem Physiol B Biochem Mol Biol 120: 517-525.
20. Vaisar T, Pennathur S, Green PS, Gharib SA, Hoofnagle AN, et al. (2007) Shotgun proteomics implicates protease inhibition and complement activation in the antiinflammatory properties of HDL. J Clin Invest 117: 746-756.
21. Hoofnagle AF, Heinecke JW, (2009) Lipoproteomics: using mass spectrometry-based proteomics to explore the assembly, structures, and functions of lipoproteins. J Lipid Res.
22. Gordon SM, Hofmann S, Askew DS, Davidson WS, (2011) High density lipoprotein: it's not just about lipid transport anymore. Trends Endocrinol Metab 22: 9-15.
23. Davidson WS, Silva RA, Chantepie S, Lagor WR, Chapman MJ, et al. (2009) Proteomic analysis of defined HDL subpopulations reveals particle-specific protein clusters: relevance to antioxidative function. Arterioscler Thromb Vasc Biol 29: 870-876.
24. Davidsson P, Hulthe J, Fagerberg B, Camejo G, (2010) Proteomics of apolipoproteins and associated proteins from plasma high-density lipoproteins. Arterioscler Thromb Vasc Biol 30: 156-163.
25. Morton RE, Gnizak HM, Greene DJ, Cho KH, Paromov VM, (2008) Lipid transfer inhibitor protein (apolipoprotein F) concentration in normolipidemic and hyperlipidemic subjects. J Lipid Res 49: 127-135.
26. Vaughan AM, Oram JF, (2005) ABCG1 redistributes cell cholesterol to domains removable by high density lipoprotein but not by lipid-depleted apolipoproteins. J Biol Chem 280: 30150-30157.
27. Korstanje R, Albers JJ, Wolfbauer G, Li R, Tu AY, et al. (2004) Quantitative trait locus mapping of genes that regulate phospholipid transfer activity in SM/J and NZB/BlNJ inbred mice. Arterioscler Thromb Vasc Biol 24: 155-160.
28. Contois J, McNamara JR, Lammi-Keefe C, Wilson PW, Massov T, et al. (1996) Reference intervals for plasma apolipoprotein A-1 determined with a standardized commercial immunoturbidimetric assay: results from the Framingham Offspring Study. Clin Chem 42: 507-514.
29. Massey JB, Pownall HJ, Macha S, Morris J, Tubb MR, et al. (2009) Mass spectrometric determination of apolipoprotein molecular stoichiometry in reconstituted high density lipoprotein particles. J Lipid Res 50: 1229-1236.
30. Teslovich TM, Musunuru K, Smith AV, Edmondson AC, Stylianou IM, et al. (2010) Biological, clinical and population relevance of 95 loci for blood lipids. Nature 466: 707-713.
31. Green PS, Vaisar T, Pennathur S, Kulstad JJ, Moore AB, et al. (2008) Combined statin and niacin therapy remodels the high-density lipoprotein proteome. Circulation 118: 1259-1267.
32. Tu AY, Albers JJ, (2001) Functional analysis of the transcriptional activity of the mouse phospholipid transfer protein gene. Biochem Biophys Res Commun 287: 921-926.
33. Jiang XC, Bruce C, Mar J, Lin M, Ji Y, et al. (1999) Targeted mutation of plasma phospholipid transfer protein gene markedly reduces high-density lipoprotein levels. J Clin Invest 103: 907-914.
34. Wu T, Lee CG, Buckler-White A, Kozak CA, (2002) Genetic control of a mouse serum lipoprotein factor that inactivates murine leukemia viruses: evaluation of apolipoprotein F as a candidate. J Virol 76: 2279-2286.
35. Leong JC, Kane JP, Oleszko O, Levy JA, (1977) Antigen-specific nonimmunoglobulin factor that neutralizes xenotropic virus is associated with mouse serum lipoproteins. Proc Natl Acad Sci U S A 74: 276-280.
36. Kane JP, Hardman DA, Dimpfl JC, Levy JA, (1979) Apolipoprotein is responsible for neutralization of xenotropic type C virus by mouse serum. Proc Natl Acad Sci U S A 76: 5957-5961.
37. Montelaro RC, Fischinger PJ, Larrick SB, Dunlop NM, Ihle JN, et al. (1979) Further characterization of the oncornavirus inactivating factor in normal mouse serum. Virology 98: 20-34.
38. Lagor WR, de Groh ED, Ness GC, (2005) Diabetes alters the occupancy of the hepatic 3-hydroxy-3-methylglutaryl-CoA reductase promoter. J Biol Chem 280: 36601-36608.
39. Brown RJ, Edmondson AC, Griffon N, Hill TB, Fuki IV, et al. (2009) A naturally occurring variant of endothelial lipase associated with elevated HDL exhibits impaired synthesis. J Lipid Res 50: 1910-1916.
40. Wu K, Joffre C, Li X, MacVeigh-Aloni M, Hom M, et al. (2009) Altered expression of genes functioning in lipid homeostasis is associated with lipid deposition in NOD mouse lacrimal gland. Exp Eye Res 89: 319-332.
41. Cohn JS, McNamara JR, Cohn SD, Ordovas JM, Schaefer EJ, (1988) Plasma apolipoprotein changes in the triglyceride-rich lipoprotein fraction of human subjects fed a fat-rich meal. J Lipid Res 29: 925-936.
42. Gerdes LU, Gerdes C, Klausen IC, Faergeman O, (1992) Generation of analytic plasma lipoprotein profiles using two prepacked superose 6B columns. Clin Chim Acta 205: 1-9.
43. Miao B, Zondlo S, Gibbs S, Cromley D, Hosagrahara VP, et al. (2004) Raising HDL cholesterol without inducing hepatic steatosis and hypertriglyceridemia by a selective LXR modulator. J Lipid Res 45: 1410-1417.
44. Carr TP, Andresen CJ, Rudel LL, (1993) Enzymatic determination of triglyceride, free cholesterol, and total cholesterol in tissue lipid extracts. Clin Biochem 26: 39-42.
45. Asztalos BF, de la Llera-Moya M, Dallal GE, Horvath KV, Schaefer EJ, et al. (2005) Differential effects of HDL subpopulations on cellular ABCA1- and SR-BI-mediated cholesterol efflux. J Lipid Res 46: 2246-2253.
46. Adorni MP, Zimetti F, Billheimer JT, Wang N, Rader DJ, et al. (2007) The roles of different pathways in the release of cholesterol from macrophages. J Lipid Res 48: 2453-2462.
47. Boone LR, Lagor WR, de la Llera Moya M, Niesen MI, Rothblat GH, et al. (2011) Thyroid hormone enhances the ability of serum to accept cellular cholesterol via the ABCA1 transporter. Atherosclerosis.