Opposing roles of glucocorticoid receptor and mineralocorticoid receptor in trimethyltin-induced cytotoxicity in the mouse hippocampus

Neuroscience Letters

Volumn 511, Issue 2, 2012, Pages 116-119

  Ogita, Kiyokazu ^a   Sugiyama, Chie ^a,b   Acosta, Gabriela Beatriz ^a,c   Kuramoto, Nobuyuki ^a   Shuto, Makoto ^a   Yoneyama, Masanori ^a   Nakamura, Yukary ^a   Shiba, Tatsuo ^a   Yamaguchi, Taro ^a  

^a SETSUNAN UNIVERSITY   (Japan)

^b YASUDA WOMEN'S UNIVERSITY   (Japan)

^c UNIVERSIDAD DE BUENOS AIRES   (Argentina)

Author keywords

Glucocorticoid receptor hippocampus; Mineralocorticoid receptor; Trimethyltin

Indexed keywords

ALDOSTERONE; CORTICOSTERONE; GLUCOCORTICOID RECEPTOR; MIFEPRISTONE; MINERALOCORTICOID RECEPTOR; SPIRONOLACTONE; TRIMETHYLTIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN TISSUE; CELL PROTECTION; CONTROLLED STUDY; CORTICOSTERONE BLOOD LEVEL; CYTOTOXICITY; DISEASE EXACERBATION; FLUORESCENCE MICROSCOPY; GRANULE CELL; HIPPOCAMPUS; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; MALE; MOUSE; NERVE CELL; NEUROMODULATION; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ALDOSTERONE; ANIMALS; CORTICOSTERONE; HIPPOCAMPUS; MICE; MINERALOCORTICOID RECEPTOR ANTAGONISTS; RECEPTORS, GLUCOCORTICOID; RECEPTORS, MINERALOCORTICOID; SPIRONOLACTONE; TRIMETHYLTIN COMPOUNDS;

EID: 84857372411     PISSN: 03043940     EISSN: 18727972     Source Type: Journal    
DOI: 10.1016/j.neulet.2012.01.052     Document Type: Article

References (22)

1. Dallman M.F., Akana S.F., Jacobson L., Levin N., Cascio C.S., Shinsako J. Characterization of corticosterone feedback regulation of ACTH secretion. Ann. N.Y. Acad. Sci. 1987, 512:402-414.
2. De Bosscher K., VandenBerghe W., Haegeman G. The interplay between the glucocorticoid receptor and nuclear factor-kappaB or activator protein-1: molecular mechanisms for gene repression. Endocr. Rev. 2003, 24:488-522.
3. Herman J.P., Patel P.D., Akil H., Watson S.J. Localization and regulation of glucocorticoid and mineralocorticoid receptor messenger RNAs in the hippocampal formation of the rat. Mol. Endocrinol. 1989, 3:1886-1894.
4. Imai H., Kabuto M., Takita M., Kato N. Interleukin-1 receptor antagonist inhibits transient increase of plasma corticosterone in the initial phase of trimethyltin-induced hippocampal necrosis. Neurotoxicology 1998, 19:163-166.
5. Imai H., Nishimura T., Sadamatsu M., Liu Y., Kabuto M., Kato N. Type II glucocorticoid receptors are involved in neuronal death and astrocyte activation induced by trimethyltin in the rat hippocampus. Exp. Neurol. 2001, 17:22-28.
6. Irita J., Okura T., Kurata M., Miyoshi K., Fukuoka T., Higaki J. Osteopontin in rat renal fibroblasts: functional properties and transcriptional regulation by aldosterone. Hypertension 2008, 51:507-513.
7. Kawada K., Yoneyama M., Nagashima R., Ogita K. In vivo acute treatment with trimethyltin chloride causes neuronal degeneration in the murine olfactory bulb and anterior olfactory nucleus by different cascades in each region. J. Neurosci. Res. 2008, 86:1635-1646.
8. Lai M., Horsburgh K., Bae S.E., Carter R.N., Stenvers D.J., Fowler J.H., Yau J.L., Gomez-Sanchez C.E., Holmes M.C., Kenyon C.J., Seckl J.R., Macleod M.R. Forebrain mineralocorticoid receptor overexpression enhances memory, reduces anxiety and attenuates neuronal loss in cerebral ischaemia. Eur. J. Neurosci. 2007, 25:1832-1842.
9. Min L.J., Mogi M., Iwanami J., Sakata A., Jing F., Tsukuda K., Ohshima K., Horiuchi M. Angiotensin II and aldosterone-induced neuronal damage in neurons through an astrocyte-dependent mechanism. Hypertens. Res. 2011, 34:773-778.
10. Ogita K., Nitta Y., Watanabe Y., Nakatani Y., Nishiyama N., Sugiyama C., Yoneda Y. In vivo activation of c-Jun N-terminal kinase signaling cascade prior to granule cell death induced by trimethyltin in the dentate gyrus of mice. Neuropharmacology 2004, 47:619-630.
11. Ogita K., Nishiyama N., Sugiyama C., Higuchi K., Yoneyama M., Yoneda Y. Regeneration of granule neurons after lesioning of hippocampal dentate gyrus: evaluation using adult mice treated with trimethyltin chloride as a model. J. Neurosci. Res. 2005, 82:609-621.
12. Reul J.M., deKloet E.R. Two receptor systems for corticosterone in rat brain: microdistribution and differential occupation. Endocrinology 1985, 117:2505-2511.
13. Rogalska J. Mineralocorticoid and glucocorticoid receptors in hippocampus: their impact on neurons survival and behavioral impairment after neonatal brain injury. Vitam. Horm. 2010, 82:391-419.
14. Schmued L.C., Hopkins K.J. Fluoro-Jade: novel fluorochromes for detecting toxicant-induced neuronal degeneration. Toxicol. Pathol. 2000, 28:91-99.
15. Shuto M., Higuchi K., Sugiyama C., Yoneyama M., Kuramoto N., Nagashima R., Kawada K., Ogita K. Endogenous and exogenous glucocorticoids prevent trimethyltin from causing neuronal degeneration of the mouse brain in vivo: involvement of oxidative stress pathways. J. Pharmacol. Sci. 2009, 110:424-436.
16. Stumpf W.E., Heiss C., Sar M., Duncan G.E., Craver C. Dexamethasone and corticosterone receptor sites. Differential topographic distribution in rat hippocampus revealed by high resolution autoradiography. Histochemistry 1989, 92:201-210.
17. Tsutsumi S., Akaike M., Arimitsu H., Imai H., Kato N. Circulating corticosterone alters the rate of neuropathological and behavioral changes induced by trimethyltin in rats. Exp. Neurol. 2002, 173:86-94.
18. Unlap T., Jope R.S. Inhibition of NFkB DNA binding activity by glucocorticoids in rat brain. Neurosci. Lett. 1995, 198:41-44.
19. Wang Z., Kang J.S., Li Y., Yuan Z.X., Liu S.S., Sun L.K. The effects of dexamethasone on rat brain cortical nuclear factor kappa B (NF-kappaB) in endotoxic shock. Toxicol. Appl. Pharmacol. 2006, 214:263-269.
20. Wenzel A., Grimm C., Seeliger M.W., Jaissle G., Hafezi F., Kretschmer R., Zrenner E., Remé C.E. Prevention of photoreceptor apoptosis by activation of the glucocorticoid receptor. Invest. Ophthalmol. Vis. Sci. 2001, 42:1653-1659.
21. Yoneyama M., Nishiyama N., Shuto M., Sugiyama C., Kawada K., Seko K., Nagashima R., Ogita K. In vivo depletion of endogenous glutathione facilitates trimethyltin-induced neuronal damage in the dentate gyrus of mice by enhancing oxidative stress. Neurochem. Int. 2008, 52:761-769.
22. Yoneyama M., Iwamoto N., Nagashima R., Sugiyama C., Kawada K., Kuramoto N., Shuto M., Ogita K. Altered expression of heat shock protein 110 family members in mouse hippocampal neurons following trimethyltin treatment in vivo and in vitro. Neuropharmacology 2008, 55:693-703.