Dual surface modification with PEG and corn trypsin inhibitor: Effect of PEG:CTI ratio on protein resistance and anticoagulant properties

Journal of Biomedical Materials Research - Part A

Volumn 100 A, Issue 4, 2012, Pages 856-862

  Alibeik, Sara ^a   Zhu, Shiping ^a   Yau, Jonathan W ^a   Weitz, Jeffrey I ^a   Brash, John L ^a  

^a MCMASTER UNIVERSITY   (Canada)

Author keywords

anticoagulant; bioactive surface; blood compatibility; polyethylene glycol protein conjugate; protein resistant surface; surface modification

Indexed keywords

ANTICOAGULANT; ANTICOAGULANT PROPERTIES; BINARY SOLUTIONS; BIOACTIVE SURFACES; BLOOD COMPATIBILITY; CLOTTING TIME; FIBRINOGEN ADSORPTION; GOLD SUBSTRATES; GOLD SURFACES; HUMAN PLASMAS; PROTEIN RESISTANCE; PROTEIN RESISTANT SURFACES; PROTEIN-RESISTANT PROPERTIES; RADIOLABELING; TRYPSIN INHIBITOR; WATER CONTACT ANGLE;

ADSORPTION; BIOACTIVITY; CONTACT ANGLE; GOLD; POLYETHYLENE GLYCOLS; SURFACE TREATMENT;

PROTEINS;

ALPHA LACTALBUMIN; BLOOD CLOTTING FACTOR 12A; BUFFER; CORN TRYPSIN INHIBITOR; FIBRINOGEN; GOLD; MACROGOL; TRYPSIN INHIBITOR; UNCLASSIFIED DRUG;

ADSORPTION; ANTICOAGULATION; ARTICLE; BLOOD CLOTTING TIME; CONTACT ANGLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG ADSORPTION; DRUG CONJUGATION; ELLIPSOMETRY; HUMAN; IMMOBILIZATION; ISOTOPE LABELING; PLASMA;

ANTICOAGULANTS; PLANT PROTEINS; POLYETHYLENE GLYCOLS; PROTEINS;

EID: 84857370836     PISSN: 15493296     EISSN: 15524965     Source Type: Journal    
DOI: 10.1002/jbm.a.34022     Document Type: Article

References (30)

1. Labarre D,. Improving blood-compatibility of polymeric surfaces. Trends Biomater Artif Organs 2001; 15:1-3.
2. Sefton MV, Gemmell CH, Gorbet MB,. What really is blood compatibility? J Biomater Sci Polym Ed 2000; 11: 1165-1182.
3. Brash JL, Tenhove P,. Protein adsorption studies on standard polymeric materials. J Biomater Sci Polym Ed 1993; 4: 591-599.
4. Wu YG, Simonovsky FI, Ratner BD, Horbett TA,. The role of adsorbed fibrinogen in platelet adhesion to polyurethane surfaces: A comparison of surface hydrophobicity, protein adsorption, monoclonal antibody binding, and platelet adhesion. J Biomed Mater Res A 2005; 74A: 722-738.
5. Gorbet MB, Sefton MV,. Biomaterial-associated thrombosis: Roles of coagulation factors, complement, platelets and leukocytes. Biomaterials 2004; 25: 5681-5703.
6. Jin ZL, Brash JL, Zhu SP,. ATRP grafting of oligo(ethylene glycol) methacrylates from gold surface-Effect of monomer size on grafted chain and EO unit densities. Can J Chem Rev Can Chim 2010;88: 411-417.
7. Brash JL,. Exploiting the current paradigm of blood-material interactions for the rational design of blood-compatible materials. J Biomater Sci Polym Ed 2000; 11: 1135-1146.
8. Unsworth LD, Sheardown H, Brash JL,. Polyethylene oxide surfaces of variable chain density by chemisorption of PEO-thiol on gold: Adsorption of proteins from plasma studied by radiolabelling and immunoblotting. Biomaterials 2005; 26: 5927-5933.
9. Zhang Z, Zhang M, Chen SF, Horbetta TA, Ratner BD, Jiang SY,. Blood compatibility of surfaces with superlow protein adsorption. Biomaterials 2008; 29: 4285-4291.
10. McClung WG, Clapper DL, Hu SP, Brash JL,. Adsorption of plasminogen from human plasma to lysine-containing surfaces. J Biomed Mater Res 2000; 49: 409-414.
11. Martins MCL, Curtin SA, Freitas SC, Salgueiro P, Ratner BD, Barbosa MA,. Molecularly designed surfaces for blood deheparinization using an immobilized heparin-binding peptide. J Biomed Mater Res A 2009; 88A: 162-173.
12. Yang Z, Wang J, Luo R, Maitz MF, Jing F, Sun H, Huang N,. The covalent immobilization of heparin to pulsed-plasma polymeric allylamine films on 316L stainless steel and the resulting effects on hemocompatibility. Biomaterials 2010; 31: 2072-2083.
13. Murugesan S, Xie J, Linhardt RJ,. Immobilization of heparin: Approaches and applications. Curr Top Med Chem 2008; 8: 80-100.
14. Li D, Chen H, McClung WG, Brash JL,. Lysine-PEG-modified polyurethane as a fibrinolytic surface: Effect of PEG chain length on protein interactions, platelet interactions and clot lysis. Acta Biomater 2009; 5: 1864-1871.
15. Sask KN, Zhitomirsky I, Berry LR, Chan AKC, Brash JL,. Surface modification with an antithrombin-heparin complex for anticoagulation: Studies on a model surface with gold as substrate. Acta Biomater 2010; 6: 2911-2919.
16. Alibeik S, Zhu S, Brash JL,. Surface modification with PEG and hirudin for protein resistance and thrombin neutralization in blood contact. Coll Surf B Biointerf 2010; 81: 389-396.
17. Pedersen LC, Yee VC, Vondassow G, Hazeghazam M, Reeck GR, Stenkamp RE, Teller DC,. The corn inhibitor of blood-coagulation factor Xiia-Crystallization and preliminary crystallographic analysis. J Mol Biol 1994; 236: 385-387.
18. Alibeik S, Zhu S, Yau JW, Weitz JI, Brash JL,. Surface modification with polyethylene glycol-corn trypsin inhibitor conjugate for inhibition of contact factor pathway on blood-contacting surfaces. Acta Biomater 2011;7:4177-4186.
19. Knight LC, Budzynski AZ, Olexa SA,. Radiolabeling of fibrinogen using the Lodogen technique. Thromb Hemost 1981; 46: 593-596.
20. Tokumitsu S, Liebich A, Herrwerth S, Eck W, Himmelhaus M, Grunze M,. Grafting of alkanethiol-terminated poly(ethylene glycol) on gold. Langmuir 2002; 18: 8862-8870.
21. Tosatti S, De Paul SM, Askendal A, VandeVondele S, Hubbell JA, Tengvall P, Textor M,. Peptide functionalized poly(L -lysine)-g-poly(ethylene glycol) on titanium: Resistance to protein adsorption in full heparinized human blood plasma. Biomaterials 2003; 24: 4949-4958.
22. Unsworth LD, Tun Z, Sheardown H, Brash JL,. Chemisorption of thiolated poly(ethylene oxide) to gold: Surface chain densities measured by ellipsometry and neutron reflectometry. J Coll Interf Sci 2005; 281: 112-121.
23. Price ME, Cornelius RM, Brash JL,. Protein adsorption to polyethylene glycol modified liposomes from fibrinogen solution and from plasma. Biochim Biophys Acta Biomembr 2001; 1512: 191-205.
24. Du YJ, Cornelius RM, Brash JL,. Measurement of protein adsorption to gold surface by radioiodination methods: Suppression of free iodide sorption. Colloids Surf B Biointerf 2000; 17: 59-67.
25. Jin ZL, Feng W, Beisser K, Zhu SP, Sheardown H, Brash JL,. Protein-resistant polyurethane prepared by surface-initiated atom transfer radical graft polymerization (ATRgP) of water-soluble polymers: Effects of main chain and side chain lengths of grafts. Colloids Surf B Biointerf 2009; 70: 53-59.
26. Unsworth LD, Sheardown H, Brash JL,. Protein resistance of surfaces prepared by sorption of end-thiolated poly(ethylene glycol) to gold: Effect of surface chain density. Langmuir 2005; 21: 1036-1041.
27. Feng W, Brash JL, Zhu SP,. Nonbiofouling materials prepared by atom transfer radical polymerization grafting of 2-methacryloloxyethyl phosphorylcholine: Separate effects of graft density and chain length on protein repulsion. Biomaterials 2006; 27: 847-855.
28. Jin ZL, Feng W, Zhu SP, Sheardown H, Brash JL,. Protein-resistant polyurethane by sequential grafting of poly(2-hydroxyethyl methacrylate) and poly(oligo(ethylene glycol) methacrylate) via surface-initiated ATRP. J Biomed Mater Res A 2010; 95A: 1223-1232.
29. Alibeik S, Zhu S, Yau J, Weitz J, Brash J,. Modification of polyurethane with polyethylene glycol-corn trypsin inhibitor for inhibition of factor XIIa in blood contact. J Biomater Sci Polym Ed; in press. DOI: 10.1163/ 092050611X603250.
30. Lee JH, Lee HB, Andrade JD,. Blood compatibility of polyethylene oxide surfaces. Prog Polym Sci 1995; 20: 1043-1079.