Thermally-triggered 'off-on-off' response of gadolinium-hydrogel-lipid hybrid nanoparticles defines a customizable temperature window for non-invasive magnetic resonance imaging thermometry

Journal of Controlled Release

Volumn 157, Issue 3, 2012, Pages 478-484

  Shuhendler, Adam J ^a   Staruch, Robert ^b,c   Oakden, Wendy ^b,c   Gordijo, Claudia R ^a   Rauth, Andrew M ^b,d   Stanisz, Greg J ^b,c   Chopra, Rajiv ^b,c   Wu, Xiao Yu ^a  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c Sunnybrook Health Sciences Centre   (Canada)

^d PRINCESS MARGARET HOSPITAL   (Canada)

Author keywords

Hydrogel lipid hybrid nanoparticles; Keywords; Magnetic resonance imaging; T1 weighted; Temperature responsive contrast agent; Thermometry; Thermotherapy

Indexed keywords

HYBRID NANOPARTICLE; KEYWORDS; T1-WEIGHTED; TEMPERATURE RESPONSIVE CONTRAST AGENT; THERMOMETRY; THERMOTHERAPIES;

ACRYLIC MONOMERS; AMIDES; CHELATION; GADOLINIUM; MAGNETIC RESONANCE IMAGING; NANOPARTICLES; PHASE TRANSITIONS; PHYSICAL THERAPY; THERMOMETERS; TISSUE;

HYDROGELS;

GADOLINIUM; SOLID LIPID NANOPARTICLE;

ARTICLE; CHELATION; CONTRAST ENHANCEMENT; DRUG RESPONSE; ENCAPSULATION; HYDROGEL; NON INVASIVE PROCEDURE; NUCLEAR MAGNETIC RESONANCE IMAGING; PHASE TRANSITION; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TEMPERATURE; THERMOMETRY;

ACETIC ACIDS; ACRYLIC RESINS; CHELATING AGENTS; CONTRAST MEDIA; DRUG CARRIERS; GADOLINIUM; HOT TEMPERATURE; HYDROGELS; MAGNETIC RESONANCE IMAGING; NANOPARTICLES; POLYETHYLENE GLYCOLS;

EID: 84857363962     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2011.09.061     Document Type: Article

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