SIK3 is essential for chondrocyte hypertrophy during skeletal development in mice

Development

Volumn 139, Issue 6, 2012, Pages 1153-1163

  Sasagawa, Satoru ^a,b,e   Takemori, Hiroshi ^c   Uebi, Tatsuya ^c   Ikegami, Daisuke ^a   Hiramatsu, Kunihiko ^a   Ikegawa, Shiro ^d   Yoshikawa, Hideki ^a   Tsumaki, Noriyuki ^a,b,f  

^a OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^c NATIONAL INSTITUTE OF BIOMEDICAL INNOVATION   (Japan)

^d RIKEN   (Japan)

^e OSAKA MEDICAL CENTER FOR CANCER AND CARDIOVASCULAR DISEASES   (Japan)

^f KYOTO UNIVERSITY   (Japan)

Author keywords

Chondrocyte hypertrophy; Col11a2; Endochondral bone formation; HDAC4; Knockout mouse; SIK3

Indexed keywords

HISTONE DEACETYLASE 4; PROTEIN KINASE; SALT INDUCIBLE KINASE 3; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ARTICULAR CARTILAGE; BODY SIZE; BONE DEVELOPMENT; BONE DISEASE; BONE TISSUE; CARTILAGE CELL; CELL EXPANSION; CELL NUCLEUS; CHONDROCYTE HYPERTROPHY; CONTROLLED STUDY; CYTOPLASM; DWARFISM; EMBRYO DEVELOPMENT; ENZYME DEFICIENCY; FEMALE; HISTOPATHOLOGY; HUMERUS; LIMB; MALE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RIB; SALT INDUCIBLE KINASE 3 DEFICIENCY; SKULL; SPINE; STERNUM;

ANIMALS; BONE AND BONES; BONE DEVELOPMENT; CELL DIFFERENTIATION; CELL NUCLEUS; CELLS, CULTURED; CHONDROCYTES; CHONDROGENESIS; COLLAGEN TYPE XI; DWARFISM; EMBRYO, MAMMALIAN; GROWTH PLATE; HISTONE DEACETYLASES; HYPERTROPHY; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; MYOGENIC REGULATORY FACTORS; OSTEOGENESIS; PROTEIN-SERINE-THREONINE KINASES;

EID: 84857254443     PISSN: 09501991     EISSN: 14779129     Source Type: Journal    
DOI: 10.1242/dev.072652     Document Type: Article

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