Simple conversion of fully protected amino acids to zwitterions

Tetrahedron Letters

Volumn 53, Issue 12, 2012, Pages 1433-1434

  Hao, Junliang ^a   Reinhard, Matt ^a   Henry, Steven S ^a   Seest, Eric P ^a   Belvo, Matthew D ^a   Monn, James A ^a  

^a ELI LILLY AND COMPANY   (United States)

Author keywords

Amino acids deprotection; mGlu receptors; Microwave assisted synthesis; Zwitterions

Indexed keywords

AMINO ACID DERIVATIVE; AMPHOLYTE;

ACIDITY; ARTICLE; BIOTRANSFORMATION; ION EXCHANGE CHROMATOGRAPHY; ISOELECTRIC POINT; PRECIPITATION;

EID: 84857237175     PISSN: 00404039     EISSN: 18733581     Source Type: Journal    
DOI: 10.1016/j.tetlet.2012.01.033     Document Type: Article

References (4)

1. T.W. Greene, and P.G.M. Wuts Protective Groups in Organic Synthesis 1999 John Wiley & Sons New York
2. M.G. Moloney Nat. Prod. Rep. 19 2002 597 616
3. J.A. Monn, M.J. Valli, S.M. Massey, R.A. Wright, C.R. Salhoff, B.G. Johnson, T. Howe, C.A. Alt, G.A. Rhodes, R.L. Robey, K.R. Griffey, J.P. Tizzano, M.J. Kallman, D.R. Helton, and D.D. Schoepp J. Med. Chem. 40 1997 528 537
4. C. Dominguez, L. Prieto, M.J. Valli, S.M. Massey, M. Bures, R.A. Wright, B.G. Johnson, S.L. Andis, A. Kingston, D.D. Schoepp, and J.A. Monn J. Med. Chem. 48 2005 3605 3612