Paradoxical cognitive capacities in dual diagnosis schizophrenia: The quest for explanatory factors

Journal of Dual Diagnosis

Volumn 8, Issue 1, 2012, Pages 35-47

  Potvin, Stéphane ^a,b   Stavro, Katherine ^a,b   Pelletier, Julie ^a  

^a CENTRE DE RECHERCHE FERNAND SEGUIN   (Canada)

^b UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

cognition; schizophrenia; substance use disorder

Indexed keywords

ALCOHOL; AMPHETAMINE; CANNABIS; COCAINE; PHENCYCLIDINE;

COCAINE DEPENDENCE; COGNITION; COGNITIVE DEFECT; COMORBIDITY; CROSS-SECTIONAL STUDY; HUMAN; IMPULSIVENESS; MEDLINE; PSYCHOMOTOR ACTIVITY; REVIEW; SCHIZOPHRENIA; SCHIZOPHRENIA SPECTRUM DISORDER; TASK PERFORMANCE; VERBAL MEMORY;

EID: 84857207186     PISSN: 15504263     EISSN: 15504271     Source Type: Journal    
DOI: 10.1080/15504263.2012.648549     Document Type: Review

References (103)

1. Addington, J., and, Addington, D. 1997. Substance abuse and cognitive functioning in schizophrenia. Journal of Psychiatry Neuroscience, 22: 99-104. (Pubitemid 127488583)
2. Allen, D. N., Goldstein, G., Forman, S. D., Kashavan, M. S., van Kammen, D. P., and, Sanders, R. D. 2000. Neurologic examination abnormalities in schizophrenia with and without a history of alcoholism. Neuropsychiatry Neuropsychology and Behavioural Neurology, 13 (3): 184-187. (Pubitemid 30495479)
3. Allen, D. N., and, Remy, C. J. 2000. Neuropsychological deficits in patients with schizophrenia and alcohol dependence. Archives of Clinical Neuropsychology, 15: 762-763.
4. Allen, D. N., Goldstein, G., and, Aldarondo, F. 1999. Neurocognitive dysfunction in patients diagnosed with schizophrenia and alcoholism. Neuropsychology, 13: 62-68. doi: 10.1037/0894-4105.13.1.62 (Pubitemid 29066439)
5. Ameri, A. 1999. The effects of cannabinoids on the brain. Progress in Neurobiology, 58 (4): 315-348. doi: 10.1016/S0301-0082(98)00087-2 (Pubitemid 29230000)
6. Barnes, T. R. E., Mutsatsa, S. H., Hutton, S. B., Watt, H. C., and, Joyce, E. M. 2006. Comorbid substance use and age at onset of schizophrenia. The British Journal of Psychiatry, 188: 237-242. doi: 10.1192/ bjp.bp.104.007237 (Pubitemid 43341651)
7. Bates, M. E., Bowden, S. C., and, Barry, D. 2002. Neurocognitive impairment associated with alcohol use disorders: Implications for treatment. Experimental and Clinical Psychopharmacology, 10 (3): 193-212. doi: 10.1037/1064-1297.10.3.193 (Pubitemid 34919929)
8. Bechara, A., Tranel, D., and, Damasio, H. 2000. Characterization of the decision-making impairment of patients with bilateral lesions of the ventromedial prefrontal cortex. Brain, 123: 189-202 doi: 10.1093/ brain/123.11.2189
9. Bilder, R. M., Goldman, R. S., Robinson, D., Reiter, G., Bell, L., Bates, J. A., and, Lieberman, J. A. 2000. Neuropsychology of first-episode schizophrenia: Initial characterization and clinical correlates. American Journal of Psychiatry, 157 (4): 549-559 doi: 10.1176/appi.ajp.157.4.549 (Pubitemid 30191193)
10. Bowie, C. R., Serper, M. R., Riggio, S., and, Harvey, P. D. 2005. Neurocognition, symptomatology, and functional skills in older alcohol-abusing schizophrenia patients. Schizophrenia Bulletin, 31 (1): 175-182. doi: 10.1093/jschbul/sbi001 (Pubitemid 41214366)
11. Caplan, B., Schutt, R. K., Turner, W. M., Goldfinger, S. M., and, Seidman, L. J. 2006. Change in neurocognition by housing type and substance abuse among formerly homeless seriously mentally ill persons. Schizophrenia Research, 83 (1): 77-86. doi: 10.1016/j.schres.2005.11.013
12. Carey, K. B., Carey, M. P., and, Simons, J. S. 2003. Correlates of substance use disorder among psychiatric outpatients: Focus on cognition, social role functioning, and psychiatric status. Journal of Nervous and Mental Disease, 191 (5): 300-308. doi: 10.1097/01.NMD.0000066152.87832.A9 (Pubitemid 36627204)
13. Cleghorn, J. M., Kaplan, R. D., Szechtman, B., Szechtman, H., Brown, G. M., and, Franco, S. 1991. Substance abuse and schizophrenia: Effect on symptoms but not on neurocognitive function. Journal of Clinical Psychiatry, 52 (1): 26-30.
14. Cooper, L., Liberman, D., Tucker, D., Neuchterlein, K. H., Tsuang, J., and, Barnett, H. L. 1999. Neurocognitive deficits in the dually diagnosed with schizophrenia and cocaine abuse. Psychiatric Rehabilitation Skills, 3 (2): 231-234. doi: 10.1080/10973439908408386
15. Copersino, M. L., Serper, M. R., Vadhan, N., Goldberg, B. R., Richarme, D., Chou, J. C. Y., and, Cancro, R. 2004. Cocaine craving and attentional bias in cocaine-dependent schizophrenic patients. Psychiatry Research, 128 (3): 209-218. doi: 10.1016/j.psychres.2004.07.006 (Pubitemid 39490840)
16. Coulston, C. M., Perdices, M., and, Tennant, C. C. 2007a. The neuropsychological correlates of cannabis use in schizophrenia: Lifetime abuse/dependence, frequency of use, and recency of use. Schizophrenia Research, 96 (1-3): 169-184. doi: 10.1016/j.schres.2007.08.006 (Pubitemid 47494647)
17. Coulston, C. M., Perdices, M., and, Tennant, C. C. 2007b. The neuropsychology of cannabis and other substance use in schizophrenia: Review of the literature and critical evaluation of methodological issues. Australian and New Zealand Journal of Psychiatry, 41 (11): 869-884. doi: 10.1080/ 00048670701634952 (Pubitemid 47555110)
18. De la Serna, E., Mayoral, M., Baeza, I., Arango, C., Andrés, P., Bombin, I., and, Castro-Fornieles, J. 2010. Cognitive functioning in children and adolescents in their first episode of psychosis. The Journal of Nervous and Mental Disease, 198 (2): 159-162. doi: 10.1097/NMD.0b013e3181cc0d41
19. DeRosse, P., Kaplan, A., Burdick, K. E., Lencz, T., and, Malhotra, A. K. 2010. Cannabis use disorders in schizophrenia: Effects on cognition and symptoms. Schizophrenia Research, 120 (1-3): 95-100. doi: 10.1016/ j.schres.2010.04.007
20. Dervaux, A., Baylé, F. J., Laqueille, X., Bourdel, M-C., Le Borgne, M-H., Olié, J-P., and, Krebs, M-O. 2001. Is substance abuse in schizophrenia related to impulsivity, sensation seeking or anhedonia?. American Journal of Psychiatry, 158 (3): 492-494. doi: 10.1176/appi.ajp.158.3.492 (Pubitemid 32205213)
21. Desfossés, J., Stip, E., Bentaleb, L. A., and, Potvin, S. 2010. Endocannabinoids and schizophrenia. Pharmaceuticals, 3: 3101-3126. doi: 10.3390/ph3103101
22. De Witt, H. 2009. Impulsivity as a determinant and consequence of drug use: A review of underlying processes. Addiction Biology, 14 (1): 22-31. doi: 10.1111/j.1369-1600.2008.00129.x
23. Dumais, A., Potvin, S., Joyal, C., Allaire, J. F., Stip, E., Lesage, A., and, Cté, G. 2011. Schizophrenia and serious violence: A clinical-profile incorporating impulsivity and substance-use disorders. Schizophrenia Research, 130 (1-3): 234-237. doi: 10.1016/j.schres.2011.02.024
24. Duva, S. M., Silverstein, S. M., and, Spiga, R. 2011. Impulsivity and risk-taking in co-occurring psychotic disorders and substance abuse. Psychiatry Research, 186 (2-3): 351-355. doi: 10.1016/j.psychres.2010.08. 014
25. Eyler Zorrilla, L. T., Heaton, R. K., McAdams, L. A., Zisook, S., Harris, M. J., and, Jeste, D. V. 2000. Cross-sectional study of older outpatients with schizophrenia and healthy comparison subjects: No differences in age-related cognitive decline. American Journal of Psychiatry, 157 (8): 1324-1326. doi: 10.1176/appi.ajp.157.8.1324 (Pubitemid 30659818)
26. Fein, G., Torres, J., Price, L. J., and, Di Sclafani, V. 2006. Cognitive performance in long term abstinent alcoholic individuals. Alcoholism: Clinical and Experimental Research, 30 (9): 1538-1544. doi: 10.1111/j.1530-0277.2006. 00185.x (Pubitemid 44272743)
27. Gonzalez, R., Carey, C., and, Grant, I. 2002. Nonacute (residual) neuropsychological effects of cannabis use: A qualitative analysis and systematic review. The Journal of Clinical Pharmacology, 42 (11 Suppl.): 48S-57S. doi: 10.1177/009127000223879 (Pubitemid 35205046)
28. Grant, I., Gonzalez, R., Carey, C. L., Natarajan, L., and, Wolfson, T. 2003. Non-acute (residual) neurocognitive effects of cannabis use: A meta-analytic study. Journal of the International Neuropsychological Society, 9 (5): 679-689. doi: 10.1017/S1355617703950016 (Pubitemid 36889595)
29. Green, M. F. 1996. What are the functional consequences of neurocognitive deficits in schizophrenia?. American Journal of Psychiatry, 153 (3): 321-330. (Pubitemid 26074706)
30. Green, M., and, Nuechterlein, K. 2004. The MATRICS initiative: Developing a consensus cognitive battery for clinical trials. Schizophrenia Research, 72: 1-3. doi: 10.1016/j.schres.2004.09.006 (Pubitemid 39452899)
31. Harrison, I., Joyce, E. M., Mutsatsa, S. H., Hutton, S. B., Huddy, V., Kapasi, M., and, Barnes, T. R. E. 2008. Naturalistic follow-up of comorbid substance use in schizophrenia: The West London first-episode study. Psychological Medicine, 38 (1): 79-88. doi: 10.1017/S0033291707000797 (Pubitemid 350275206)
32. Herman, M. 2004. Neurocognitive functioning and quality of life among dually-diagnosed and non-substance abusing schizophrenia in patients. International Journal of Mental Health Nursing, 13 (4): 282-291. doi: 10.1111/j.1440-0979.2004.00346.x (Pubitemid 40993929)
33. Ho, B. C., Wassink, T. H., Ziebell, S., and, Andreasen, N. C. 2011. Cannabinoid receptor 1 gene polymorphisms and marijuana misuse interactions on white matter and cognitive deficits in schizophrenia. Schizophrenia Research, 128 (1-3): 66-75. doi: 10.1016/j.schres.2011.02.021
34. Jockers-Scherbl, M. C., Wolf, T., Radzei, N., Schlattmann, P., Rentzsch, J., Gómez-Carrillo de Castro, A., and, Khl, K. P. 2007. Cannabis induces different cognitive changes in schizophrenic patients and in healthy controls. Progress in Neuropsychopharmacology and Biological Psychiatry, 31 (5): 1054-1063. doi: 10.1016/j.pnpbp.2007.03.006 (Pubitemid 46824020)
35. Jovanovski, E., Erb, S., and, Zakzanis, K. K. 2005. Neurocognitive deficits in cocaine users: A quantitative review of the evidence. Journal of Clinical and Experimental Neuropsychology, 27 (2): 189-204. doi: 10.1080/13803390490515694 (Pubitemid 40389048)
36. Joyal, C. C, Hallé, P., Lapierre, D., and, Hodgins, S. 2003. Drug abuse and/or dependence and better neuropsychological performance in patients with schizophrenia. Schizophrenia Research, 63 (3): 297-299. doi: 10.1016/S0920-9964(02)00387-0 (Pubitemid 37101121)
37. Kalkstein, S., Hurford, I., and, Gur, R. C. 2010. Neurocognition in schizophrenia. Current Topics in Behavioural Neurosciences, 4: 373-390. doi: 10.1007/7854-2010-42
38. Kavanagh, D. J., McGrath, J., Saunders, J. B., Dore, G., and, Clark, D. 2002. Substance misuse in patients with schizophrenia: Epidemiology and management. Drugs, 62 (5): 743-755. (Pubitemid 34494020)
39. Krysta, K., Krupka-Matsuszczyk, I., and, Klaslik, A. 2005. Impact of drug abuse on cognitive functioning in schizophrenia. European Neuropsychopharmacology, 15 (Suppl. 3): S579
40. Kumra, S., Thaden, E., DeThomas, C., and, Kranzler, H. 2005. Correlates of substance abuse in adolescents with treatment-refractory schizophrenia and schizoaffective disorder. Schizophrenia Research, 73 (2-3): 369-371. doi: 10.1016/j.schres.2004.08.006 (Pubitemid 40093902)
41. Leeson, V. C., Harrison, I., Ron, M. A., Barnes, T. R. E., and, Joyce, E. M. 2011. The effect of cannabis use and cognitive reserve on age at onset and psychosis outcomes in first-episode schizophrenia. In Schizophrenia Bulletin, Advance online publication. doi: 10.1093/schbul/sbq153
42. Liraud, F., and, Verdoux, H. 2002. Impact neuropsychologique de labus de substances psychoactives dans les troubles psychotiques et de lhumeur. LEncephale, 28 (2): 160-168. (Pubitemid 34627317)
43. Liraud, F., and, Verdoux, H. 2000. Which temperamental characteristics are associated with substance use in subjects with psychotic and mood disorders?. Psychiatry Research, 93 (1): 63-72. doi: 10.1016/S0165-1781(99) 00120-1 (Pubitemid 30123135)
44. Loberg, E. M., and, Hughdahl, K. 2009. Cannabis use and cognition in schizophrenia. Frontiers in Human Neuroscience, 3 (53): 1-8. doi: 10.3389/neuro.09.053.2009
45. Loberg, E. M., Hugdahl, K., and, Jorgensen, H. A. 2008. Lower neurocognitive vulnerability in schizophrenia with a history of cannabis abuse?. Schizophrenia Research, 98 (Suppl. S): 73 doi: 10.1016/ j.schres.2007.12.164
46. Loberg, E. M., Jorgensen, H. A., and, Hugdahl, K. 2003. The effects of previous drug abuse on neurocognition in schizophrenia. Journal of the International Neuropsychological Society, 9: 172
47. Lysaker, P. H., Bell, M. D., Biotty, S. M., and, Zito, W. S. 1997. Cognitive impairment and substance abuse history as predictor of the temporal stability of negative symptoms in schizophrenia. The Journal of Nervous and Mental Disease, 185 (1): 21-26. (Pubitemid 27086591)
48. Manning, V., Betteridge, S., Wanigaratne, S., Best, D., Strang, J., and, Gossop, M. 2009. Cognitive impairment in dual diagnosis inpatients with schizophrenia and alcohol use disorder. Schizophrenia Research, 114 (1-3): 98-104. doi: 10.1016/j.schres.2009.05.020
49. Manning, V., Wanigaratne, S., Best, D., Strathdee, G., Schrover, I., and, Gossop, M. 2007. Screening for cognitive functioning in psychiatric outpatients with schizophrenia, alcohol dependence, and dual diagnosis. Schizophrenia Research, 91 (1-3): 151-158. doi: 10.1016/j.schres.2006.11.019 (Pubitemid 46371278)
50. Mata, I., Rodrguez-Sánchez, J. M., Pelayo-Terán, J. M., Pérez-Iglesias, R., González-Blanch, C., Ramrez-Bonilla, M., and, Crespo-Facorro, B. 2008. Cannabis abuse is associated with decision-making impairment among first-episode patients with schizophrenia-spectrum psychosis. Psychological Medicine, 38 (9): 1257-1266. doi: 10.1017/S0033291707002218
51. McCleery, A., Addington, J., and, Addington, D. 2006. Substance misuse and cognitive functioning in early psychosis: A 2-year follow-up. Schizophrenia Research, 88 (1-3): 187-191. doi: 10.1016/j.schres.2006.06.040 (Pubitemid 44693239)
52. Mitelman, S. A., and, Buchsbaum, M. S. 2007. Very poor outcome schizophrenia: Clinical and neuroimaging aspects. International Review of Psychiatry, 19 (4): 345-357. doi: 10.1080/09540260701486563 (Pubitemid 47206976)
53. Mohamed, S., Bondi, M. W., Kasckow, J. W., Golshan, S., and, Jeste, D. V. 2006. Neurocognitive functioning in dually diagnosed middle aged and elderly patients with alcoholism and schizophrenia. International Journal of Geriatric Psychiatry, 21 (8): 711-718. doi: 10.1002/gps.1528 (Pubitemid 44322841)
54. Moore, T. H., Zammit, S., Lingford-Hughes, A., Barnes, T. R., Jones, P. B., Burke, M., and, Lewis, G. 2007. Cannabis use and risk of psychotic or affective mental health outcomes: A systematic review. The Lancet, 370 (9584): 319-328. doi: 10.1016/S0140-6736(07)61162-3 (Pubitemid 47094993)
55. Mueser, K. T., Yarnold, P. R., Rosenberg, S. D., Swett, C., Miles, K. M., and, Hill, D. 2000. Substance use disorder in hospitalized severely mentally ill psychiatric patients: Prevalence, correlates, and subgroups. Schizophrenia Bulletin, 26 (1): 179-192. (Pubitemid 30317704)
56. Mueser, K. T., Drake, R. E., and, Wallach, M. A. 1998. Dual diagnosis: A review of etiological theories. Addictive Behaviors, 23 (6): 717-734. doi: 10.1016/S0306-4603(98)00073-2 (Pubitemid 28443188)
57. Negrete, J. C. 2003. Clinical aspects of substance abuse in persons with schizophrenia. Canadian Journal of Psychiatry, 48 (1): 14-21. (Pubitemid 36331415)
58. Nixon, S. J., Hallford, G. H., and, Tivis, R. D. 1996. Neurocognitive function in alcoholic, schizophrenic, and dually diagnosed patients. Psychiatry Research, 64 (1): 35-45. doi: 10.1016/0165-1781(96)02911-3 (Pubitemid 26298081)
59. Nuechterlein, K. H., Barch, D. M., Gold, J. M., Goldberg, T. E., Green, M. F., and, Heaton, R. K. 2004. Identification of separable cognitive factors in schizophrenia. Schizophrenia Research, 72 (1): 29-39. doi: 10.1016/j.schres. 2004.09.007 (Pubitemid 39452903)
60. Peer, J., Bennett, M. E., and, Bellack, A. S. 2009. Neurocognitive characteristics of individuals with schizophrenia and cocaine dependence. Journal of Nervous and Mental Disease, 197 (8): 631-634. doi: 10.1097/NMD.0b013e3181b08bf4
61. Pencer, A., and, Addington, J. 2003. Substance use and cognition in early psychosis. Journal of Psychiatry and Neuroscience, 28 (1): 48-54. (Pubitemid 36315351)
62. Perry, J. L., and, Carroll, M. E. 2008. The role of impulsive behavior in drug abuse. Psychopharmacology, 200 (1): 1-26. doi: 10.1007/s00213-008-1173-0
63. Pope, H. G., Gruber, A. J., and, Yurgelun-Todd, D. 2001. Residual neuropsychologic effects of cannabis. Current Psychiatry Reports, 3 (6): 507-512.
64. Pope, H. G. 2002. Cannabis, cognition and residual confounding. Journal of the American Medical Association, 287 (9): 1172-1174. doi: 10.1001/jama.287.9.1172
65. Pope, H. G., Gruber, A. J., Hudson, J. I., Huestis, M. A., and, Yurgelun-Todd, D. 2002. Cognitive measures in long-term cannabis users. Journal of Clinical Pharmacology, 42 (11 Suppl.): 41S-47S. (Pubitemid 35205045)
66. Pope, H. G., Gruber, A. J., Hudson, J. I., Cohane, G., Huestis, M. A., and, Yurgelun-Todd, D. 2003. Early-onset cannabis use and cognitive deficits: What is the nature of the association?. Drug and Alcohol Dependence, 69 (3): 303-310. doi: 10.1016/S0376-8716(02)00334-4 (Pubitemid 36293942)
67. Potvin, S. 2009. Neuroimaging studies of substance abuse in schizophrenia. Current Psychiatry Reviews, 5 (4): 250-260.
68. Potvin, S., Pampoulova, T., Lipp, O., Ait Bentaleb, L., Lalonde, P., and, Stip, E. 2008. Working memory and depressive symptoms in patients with schizophrenia and substance use disorders. Cognitive Neuropsychiatry, 13 (4): 357-366. doi: 10.1080/13546800802264330 (Pubitemid 351990218)
69. Potvin, S., Joyal, C. C., Pelletier, J., and, Stip, E. 2008. Contradictory cognitive capacities among substance-abusing patients with schizophrenia: A meta-analysis. Schizophrenia Research, 100 (1-3): 242-251. doi: 10.1016/j.schres.2007.04.022 (Pubitemid 351318147)
70. Potvin, S., Sepehry, A. A., and, Stip, E. 2007. A meta-analysis of depressive symptoms in dual-diagnosis schizophrenia. Australian and New Zealand Journal of Psychiatry, 41 (10): 792-799. doi: 10.1080/ 00048670701579041 (Pubitemid 47399957)
71. Potvin, S., Sepehry, A. A., and, Stip, E. 2006. Negative symptoms in dual diagnosis schizophrenia: A meta-analysis. Psychological Medicine, 36 (4): 431-440. doi: 10.1017/S003329170500574X (Pubitemid 43380996)
72. Potvin, S., Briand, C., Prouteau, A., Bouchard, R. H., Lipp, O., Lalonde, P., and, Stip, E. 2005. CANTAB explicit memory is less impaired in addicted schizophrenia patients. Brain and Cognition, 59 (1): 38-42. doi: 10.1016/j.bandc.2005.04.002 (Pubitemid 41405838)
73. Potvin, S., Stip, E., and, Roy, J. Y. 2003. Schizophrenia and addiction: An evaluation of the self-medication hypothesis [in French]. LEncéphale, 29 (3): 193-203. doi: ENC-6-2003-29-3-0013-7006-101019-ART1 (Pubitemid 36799005)
74. Rabin, R. A., Zakzanis, K. K., and, George, T. P. 2011. The effects of cannabis use on neurocognition in schizophrenia: A meta-analysis. Schizophrenia Research, 128 (1-3): 111-116. doi: 10.1016/j.schres.2011.02.017
75. Rais, M., Cahn, W., Van Haren, N., Schnack, H., Hulshoff Pol, H., and, Kahn, R. 2008. Excessive brain volume loss over time in cannabis-using first episode schizophrenia patients. American Journal of Psychiatry, 165 (4): 490-496. doi: 10.1176/appi.ajp.2007.07071110 (Pubitemid 351694292)
76. Rentzsch, J., Penzhorn, A., Kernbichler, K., Plckl, D., Gómez-Carrillo de Castro, A., Gallinat, J., and, Jockers-Scherbl, M. C. 2007. Differential impact of heavy cannabis use on sensory gating in schizophrenic patients and otherwise healthy controls. Experimental Neurology, 205 (1): 241-249. doi: 10.1016/j.expneurol.2007.02.004 (Pubitemid 46621177)
77. Ringen, P. A., Vaskinn, A., Sundet, K., Engh, J. A., Jonsdottir, H., Simonsen, C., and, Andreassen, O. A. 2010. Opposite relationships between cannabis use and neurocognitive functioning in bipolar disorder and schizophrenia. Psychological Medicine, 40 (8): 1337-1347. doi: 10.1017/S0033291709991620
78. Rodriguez-Jimenez, R., Arages, M., Jimenez-Arriero, M. A., Ponce, G., Martinez, I., Hoenicka, J., and Psychosis and Addictions Research Group (PARG). 2008. Psychopathology and Wisconsin Card Sorting Test performance in male schizophrenic patients: Influence of dual diagnosis. Psychopathology, 41 (1): 58-64. doi: 10.1159/000110627 (Pubitemid 350146915)
79. Rodriguez-Jimenez, R., Bagney, A., Martinez-Gras, I., Ponce, G., Sanchez-Morla, E. M., Arages, M., and PARG. 2010. Executive function in schizophrenia: Influence of substance use disorder history. Schizophrenia Research, 118 (1-3): 34-40. doi: 10.1016/j.schres.2009.09.025
80. Rodriguez-Sanchez, J. M., Ayesa-Arriola, R., Mata, I., Moreno-Calle, T., Perez-Iglesias, R., Gonzalez-Blanch, C., and, Crespo-Facorro, B. 2010. Cannabis use and cognitive functioning in first-episode schizophrenia patients. Schizophrenia Research, 124 (1-3): 142-151. doi: 10.1016/j.schres.2010.08.017
81. Rogers, R. D., Moeller, F. G., Swann, A. C., and, Clark, L. 2010. Recent research on impulsivity in individuals with drug use and mental health disorders: Implications for alcoholism. Alcoholism: Clinical and Experimental Research, 34 (8): 1319-1333. doi: 10.1111/j.1530-0277.2010.01216.x
82. Ruiz-Veguilla, M., Gurpegui, M., Barrigon, M. L., Ferrin, M., Marin, E., Rubio, J. L., and, Cervilla, J. 2009. Fewer neurological soft signs among first episode psychosis patients with heavy cannabis use. Schizophrenia Research, 107 (2-3): 158-164. doi: 10.1016/j.schres.2008.08.001
83. Schiffer, B., Mller, B. W., Scherbaum, N., Forsting, M., Wiltfang, J., Leygraf, N., and, Gizewski, E. R. 2010. Impulsivity-related brain volume deficits in schizophrenia-addiction comorbidity. Brain, 133 (10): 3093-3103. doi: 10.1093/brain/awq153
84. Schnell, T., Koethe, D., Daumann, J., and, Gouzoulis-Mayfrank, E. 2009. The role of cannabis in cognitive functioning of patients with schizophrenia. Psychopharmacology, 205 (1): 45-52. doi: 10.1007/s00213-009-1512-9
85. Scholes, K. E., and, Martin-Iverson, M. T. 2010. Cannabis use and neuropsychological performance in healthy individuals and patients with schizophrenia. Psychological Medicine, 40 (10): 1635-1646. doi: 10.1017/S0033291709992078
86. Scotter, E. L., Abood, M. E., and, Glass, M. 2010. The endocannabinoid system as a target for the treatment of neurodegenerative disease. British Journal of Pharmacology, 160 (3): 480-498. doi: 10.1111/j.1476-5381.2010.00735.x
87. Serper, M. R., Bergman, A., Copersino, M. L., Chou, J. C. Y., Richarme, D., and, Cancro, R. 2002. Learning and memory impairment in cocaine-dependent and comorbid schizophrenic patients. Psychiatry Research, 93 (1): 21-32. doi: 10.1016/S0165-1781(99)00122-5
88. Serper, M. R., Copersino, M. L., Richarme, D., Vadhan, N., and, Cancro, R. 2002. Neurocognitive functioning in recently abstinent, cocaine-abusing schizophrenic patients. Journal of Substance Abuse, 11 (2): 205-213. doi: 10.1016/S0899-3289(00)00021-3
89. Sevy, S., Burdick, K. E., Visweswaraiah, H., Abdelmessih, S., Lukin, M., Yechiam, E., and, Bechara, A. 2007. Iowa gambling task in schizophrenia: A review and new data in patients with schizophrenia and co-occurring cannabis use disorders. Schizophrenia Research, 92 (1-3): 74-84. doi: 10.1016/j.schres.2007. 01.005 (Pubitemid 46561220)
90. Sevy, S., Robinson, D. G., Solloway, S., Alvir, J. M., Woerner, M. B., Bilder, R., and, Kane, J. 2001. Correlates of substance misuse in patients with first-episode schizophrenia and schizoaffective disorder. Acta Psychiatrica Scandinavica, 104 (5): 367-374. doi: 10.1111/j.1600-0447.2001.00452.x (Pubitemid 34284785)
91. Sevy, S., Kay, S. R., Opler, L., and, van Praag, H. M. 1990. Significance of cocaine history in schizophrenia. Journal of Nervous and Mental Disease, 178 (10): 642-648. (Pubitemid 20378884)
92. Smelson, D. A., Davis, C. W., Eisenstein, N., Engelhart, C., Williams, J., Losonczy, M. F., and, Ziedonis, D. 2003. Cognitive disparity in schizophrenics with and without cocaine dependency. Journal of Substance Abuse Treatment, 24 (1): 75-79. doi: 10.1016/S0740-5472(02)00324-0 (Pubitemid 36315773)
93. Smelson, D. A., Davis, C. W., Di Pano, R., Johnson, V., Losonczy, M. F., and, Ziedonis, D. 2002. Executive and motor skill functioning among cocaine-dependent schizophrenics and non-drug abusing schizophrenics. The Journal of Nervous and Mental Disease, 190 (3): 200-202. (Pubitemid 34263951)
94. Stavro, K., Pelletier, J., and, Potvin, S. 2011a. Significant deficits in problem solving persist throughout the first year of abstinence and slowly begin to remit thereafter. In Canadian College of Neuropsychopharmacology, Montréal. May
95. Stavro, K., Pelletier, J., and, Potvin, S. 2011b. Comparing short to long term deficits of verbal and visual cognitive functions: probing the lateralization hypothesis. In Canadian College of Neuropsychopharmacology, Montréal. May
96. Stip, E. 2006. Cognition, schizophrenia and the effects of antipsychotics. LEncephale, 31 (3 Pt. 1): 341-350.
97. Stirling, J., Lewis, S., Hopkins, R., and, White, C. 2005. Cannabis use prior to first onset psychosis predicts spared neurocognition at 10-year follow-up. Schizophrenia Research, 75 (1): 135-137. doi: 10.1016/ j.schres.2004.10.006 (Pubitemid 40487981)
98. Thoma, P., and, Daum, I. 2008. Working memory and multi-tasking in paranoid schizophrenia with and without comorbid substance use disorder. Addiction, 103 (5): 774-786. doi: 10.1111/j.1360-0443.2008.02156.x (Pubitemid 351537678)
99. Thoma, P., Wiebel, B., and, Daum, I. 2007. Response inhibition and cognitive flexibility in schizophrenia with and without comorbid substance use disorder. Schizophrenia Research, 92 (1-3): 168-180. doi: 10.1016/ j.schres.2007.02.004 (Pubitemid 46561240)
100. Thoma, R. J., Hanlon, F. M., Miller, G. A., Huang, M., Weisend, M. P., Sanchez, F. P., and, Canive, J. M. 2006. Neuropsychological and sensory gating deficits related to remote alcohol abuse history in schizophrenia. Journal of the International Neuropsychological Society, 12 (1): 34-44. doi: 10.1017/S1355617706060097 (Pubitemid 43379949)
101. Wobrock, T., Sittinger, H., Behrendt, B., DAmelio, R., Falkai, P., and, Caspari, D. 2007. Comorbid substance abuse and neurocognitive function in recent-onset schizophrenia. European Archives of Psychiatry and Clinical Neuroscience, 257 (4): 203-210. doi: 10.1007/s00406-006-0707-x (Pubitemid 47036718)
102. Ycel, M., Lubman, D. I., Solowij, N., and, Brewer, W. J. 2007. Understanding drug addiction: A neuropsychological perspective. Australian and New Zealand Journal of Psychiatry, 41 (12): 957-968. doi: 10.1080/ 00048670701689444 (Pubitemid 350120825)
103. Ycel, M., Bora, E., Lubman, D. I., Solowij, N., Brewer, W. J., Cotton, S. M., and, Pantelis, C. 2010. The impact of cannabis use on cognitive functioning in patients with schizophrenia: A meta-analysis of existing findings and new data in a first-episode sample. In Schizophrenia Bulletin, Advance online publication. doi: 10.1093/schbul/ sbq079