-
1
-
-
84857197083
-
Evidence of CYP3A allosterism in vivo: Analysis of interaction between fluconazole and midazolam
-
Yang, J., Atkins, W.M., Isoherranen, N., Paine, M.F. & Thummel, K.E. Evidence of CYP3A allosterism in vivo: analysis of interaction between fluconazole and midazolam. Clin. Pharmacol. Ther. 91, 442-449 (2012).
-
(2012)
Clin. Pharmacol. Ther.
, vol.91
, pp. 442-449
-
-
Yang, J.1
Atkins, W.M.2
Isoherranen, N.3
Paine, M.F.4
Thummel, K.E.5
-
2
-
-
47749131934
-
Heterotropic cooperativity in oxidation mediated by cytochrome P450
-
DOI 10.2174/138920008784746364
-
Niwa, T., Murayama, N. & Yamazaki, H. Heterotropic cooperativity in oxidation mediated by cytochrome P450. Curr. Drug Metab. 9, 453-462 (2008). (Pubitemid 352025198)
-
(2008)
Current Drug Metabolism
, vol.9
, Issue.5
, pp. 453-462
-
-
Niwa, T.1
Murayama, N.2
Yamazaki, H.3
-
3
-
-
0032735988
-
CYP3A4 drug interactions: Correlation of 10 in vitro probe substrates
-
DOI 10.1046/j.1365-2125.1999.00073.x
-
Kenworthy, K.E., Bloomer, J.C., Clarke, S.E. & Houston, J.B. CYP3A4 drug interactions: correlation of 10 in vitro probe substrates. Br. J. Clin. Pharmacol. 48, 716-727 (1999). (Pubitemid 29520596)
-
(1999)
British Journal of Clinical Pharmacology
, vol.48
, Issue.5
, pp. 716-727
-
-
Kenworthy, K.E.1
Bloomer, J.C.2
Clarke, S.E.3
Houston, J.B.4
-
4
-
-
29244447987
-
The utility of in vitro cytochrome P450 inhibition data in the prediction of drug-drug interactions
-
DOI 10.1124/jpet.105.093229
-
Obach, R.S. et al. The utility of in vitro cytochrome P450 inhibition data in the prediction of drug-drug interactions. J. Pharmacol. Exp. Ther. 316, 336-348 (2006). (Pubitemid 41832613)
-
(2006)
Journal of Pharmacology and Experimental Therapeutics
, vol.316
, Issue.1
, pp. 336-348
-
-
Obach, R.S.1
Walsky, R.L.2
Venkatakrishnan, K.3
Gaman, E.A.4
Houston, J.B.5
Tremaine, L.M.6
-
5
-
-
10744232330
-
The conduct of in vitro and in vivo drug-drug interaction studies: A Pharmaceutical Research and Manufacturers of America (PhRMA) perspective
-
DOI 10.1124/dmd.31.7.815
-
Bjornsson, T.D. et al. The conduct of in vitro and in vivo drug-drug interaction studies: a Pharmaceutical ResearcHand Manufacturers of America (PhRMA) perspective. Drug Metab. Dispos. 31, 815-832 (2003). (Pubitemid 36759050)
-
(2003)
Drug Metabolism and Disposition
, vol.31
, Issue.7
, pp. 815-832
-
-
Bjornsson, T.D.1
Callaghan, J.T.2
Einolf, H.J.3
Fischer, V.4
Gan, L.5
Grimm, S.6
Kao, J.7
King, S.P.8
Miwa, G.9
Ni, L.10
Kumar, G.11
McLeod, J.12
Obach, R.S.13
Roberts, S.14
Roe, A.15
Shah, A.16
Snikeris, F.17
Sullivan, J.T.18
Tweedie, D.19
Vega, J.M.20
Walsh, J.21
Wrighton, S.A.22
more..
-
7
-
-
4644301430
-
The structure of human microsomal cytochrome P450 3A4 determined by X-ray crystallography to 2.05-Å resolution
-
DOI 10.1074/jbc.C400293200
-
Yano, J.K. et al. The structure of human microsomal cytochrome P450 3A4 determined by X-ray crystallography to 2.05 Å resolution. J. Biol. Chem. 279, 38091-38094 (2004). (Pubitemid 39295952)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.37
, pp. 38091-38094
-
-
Yano, J.K.1
Wester, M.R.2
Schoch, G.A.3
Griffin, K.J.4
Stout, C.D.5
Johnson, E.F.6
-
8
-
-
3442896773
-
Crystal structures of human cytochrome P450 3A4 bound to metyrapone and progesterone
-
DOI 10.1126/science.1099736
-
Williams, P.A. et al. Crystal structures of human cytochrome P450 3A4 bound to metyrapone and progesterone. Science 305, 683-686 (2004). (Pubitemid 39006760)
-
(2004)
Science
, vol.305
, Issue.5684
, pp. 683-686
-
-
Williams, P.A.1
Cosme, J.2
Matak Vinkovic, D.3
Ward, A.4
Angove, H.C.5
Day, P.J.6
Vonrhein, C.7
Tickle, I.J.8
Jhoti, H.9
-
9
-
-
0032732349
-
Interaction of diclofenac and quinidine in monkeys: Stimulation of diclofenac metabolism
-
Tang, W. et al. Interaction of diclofenac and quinidine in monkeys: stimulation of diclofenac metabolism. J. Pharmacol. Exp.Ther. 291, 1068-1074 (1999).
-
(1999)
J. Pharmacol. Exp.Ther.
, vol.291
, pp. 1068-1074
-
-
Tang, W.1
-
10
-
-
0037799740
-
In vivo CYP3A4 heteroactivation is a possible mechanism for the drug interaction between felbamate and carbamazepine
-
DOI 10.1124/jpet.102.047530
-
Egnell, A.C., Houston, B. & Boyer, S. In vivo CYP3A4 heteroactivation is a possible mechanism for the drug interaction between felbamate and carbamazepine. J. Pharmacol. Exp. Ther. 305, 1251-1262 (2003). (Pubitemid 36618005)
-
(2003)
Journal of Pharmacology and Experimental Therapeutics
, vol.305
, Issue.3
, pp. 1251-1262
-
-
Egnell, A.-C.1
Houston, B.2
Boyer, S.3
|