Bacteria-reactive immune response may induce RANKL-expressing T cells in the mouse periapical bone loss lesion

Journal of Endodontics

Volumn 38, Issue 3, 2012, Pages 346-350

  Silva, Marcelo J B ^a,c   Kajiya, Mikihito ^a,b   Alshwaimi, Emad ^a,d   Sasaki, Hajime ^a,b   Hong, Jennifer ^a,b   Ok, Peter ^a,b   Rezende, Taia M B ^a,e   Pagonis, Tom C ^b   White, Robert R ^b   Paster, Bruce J ^a,b   Stashenko, Philip ^a,b   Kawai, Toshihisa ^a,b  

^a FORSYTH INSTITUTE   (United States)

^b HARVARD SCHOOL OF DENTAL MEDICINE   (United States)

^c FEDERAL UNIVERSITY OF UBERLÂNDIA   (Brazil)

^d IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY   (Saudi Arabia)

^e UNIVERSIDADE CATÓLICA DE BRASÍLIA   (Brazil)

Author keywords

Bacterial infectcion; memory T cell; periapical bone lesion; RANKL

Indexed keywords

ACID PHOSPHATASE; ACID PHOSPHATASE TARTRATE RESISTANT ISOENZYME; BACTERIAL RNA; BACTERIUM ANTIBODY; BIOLOGICAL MARKER; CD3 ANTIGEN; DIAGNOSTIC AGENT; FLUORESCEIN ISOTHIOCYANATE; FLUORESCENT DYE; IMMUNOGLOBULIN G; ISOENZYME; OSTEOCLAST DIFFERENTIATION FACTOR; RNA 16S; TARTRATE-RESISTANT ACID PHOSPHATASE; TNFSF11 PROTEIN, MOUSE;

ALVEOLAR BONE LOSS; ANIMAL; ARTICLE; BLOOD; C57BL MOUSE; CLASSIFICATION; COMPARATIVE STUDY; CONFOCAL MICROSCOPY; DISEASE MODEL; ENDODONTICS; ENTEROCOCCUS; IMMUNIZATION; IMMUNOLOGICAL MEMORY; IMMUNOLOGY; MALE; MICROBIOLOGY; MOUSE; MOUSE STRAIN; OSTEOCLAST; PASTEURELLA PNEUMOTROPICA; PASTEURELLOSIS; PATHOLOGY; T LYMPHOCYTE; TOOTH PERIAPICAL DISEASE; TOOTH PULP;

ACID PHOSPHATASE; ALVEOLAR BONE LOSS; ANIMALS; ANTIBODIES, BACTERIAL; ANTIGENS, CD3; BIOLOGICAL MARKERS; DENTAL PULP CAVITY; DENTAL PULP EXPOSURE; DISEASE MODELS, ANIMAL; ENTEROCOCCUS; FLUORESCEIN-5-ISOTHIOCYANATE; FLUORESCENT DYES; IMMUNIZATION; IMMUNOGLOBULIN G; IMMUNOLOGIC MEMORY; ISOENZYMES; MALE; MICE; MICE, INBRED C57BL; MICE, INBRED STRAINS; MICROSCOPY, CONFOCAL; OSTEOCLASTS; PASTEURELLA INFECTIONS; PASTEURELLA PNEUMOTROPICA; PERIAPICAL DISEASES; RANK LIGAND; RNA, BACTERIAL; RNA, RIBOSOMAL, 16S; T-LYMPHOCYTES;

EID: 84857194708     PISSN: 00992399     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.joen.2011.12.029     Document Type: Article

References (22)

1. I.J. Marton, and C. Kiss Protective and destructive immune reactions in apical periodontitis Oral Microbiol Immunol 15 2000 139 150 (Pubitemid 30208575)
2. P. Stashenko, R. Teles, and R. D'Souza Periapical inflammatory responses and their modulation Crit Rev Oral Biol Med 9 1998 498 521 (Pubitemid 29402013)
3. N. Kawashima, T. Okiji, T. Kosaka, and H. Suda Kinetics of macrophages and lymphoid cells during the development of experimentally induced periapical lesions in rat molars: a quantitative immunohistochemical study J Endod 22 1996 311 316 (Pubitemid 126730461)
4. P. Stashenko, and S.M. Yu T helper and T suppressor cell reversal during the development of induced rat periapical lesions J Dent Res 68 1989 830 834
5. T. Ataoglu, M. Ungor, B. Serpek, S. Haliloglu, H. Ataoglu, and H. Ari Interleukin-1beta and tumour necrosis factor-alpha levels in periapical exudates Int Endod J 35 2002 181 185
6. T. Radics, C. Kiss, I. Tar, and I.J. Marton Interleukin-6 and granulocyte-macrophage colony-stimulating factor in apical periodontitis: correlation with clinical and histologic findings of the involved teeth Oral Microbiol Immunol 18 2003 9 13 (Pubitemid 36596700)
7. D.L. Lacey, E. Timms, and H.L. Tan Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation Cell 93 1998 165 176 (Pubitemid 28180851)
8. W.S. Simonet, D.L. Lacey, and C.R. Dunstan Osteoprotegerin: a novel secreted protein involved in the regulation of bone density Cell 89 1997 309 319 (Pubitemid 27199902)
9. N. Kawashima, N. Suzuki, and G. Yang Kinetics of RANKL, RANK and OPG expressions in experimentally induced rat periapical lesions Oral Surg Oral Med Oral Pathol Oral Radiol Endod 103 2007 707 711
10. R. Vernal, A. Dezerega, and N. Dutzan RANKL in human periapical granuloma: possible involvement in periapical bone destruction Oral Dis 12 2006 283 289 (Pubitemid 43736416)
11. M. Kajiya, G. Giro, M.A. Taubman, X. Han, M.P. Mayer, and T. Kawai Role of periodontal pathogenic bacteria in RANKL-mediated bone destruction in periodontal disease J Oral Microbiol 2010 doi: 10.3402/jom.v2i0.5532
12. T. Kawai, T. Matsuyama, and Y. Hosokawa B and T lymphocytes are the primary sources of RANKL in the bone resorptive lesion of periodontal disease Am J Pathol 169 2006 987 998 (Pubitemid 44411961)
13. T. Kawai, B.J. Paster, and H. Komatsuzawa Cross-reactive adaptive immune response to oral commensal bacteria results in an induction of receptor activator of nuclear factor-kappaB ligand (RANKL)-dependent periodontal bone resorption in a mouse model Oral Microbiol Immunol 22 2007 208 215 (Pubitemid 46691094)
14. X. Zhang, and B. Peng Immunolocalization of receptor activator of NF kappa B ligand in rat periapical lesions J Endod 31 2005 574 577 (Pubitemid 41128767)
15. E. Alshwaimi, P. Purcell, and T. Kawai Regulatory T cells in mouse periapical lesions J Endod 35 2009 1229 1233
16. J.G. Fox, F.E. Dewhirst, and Z. Shen Hepatic Helicobacter species identified in bile and gallbladder tissue from Chileans with chronic cholecystitis Gastroenterology 114 1998 755 763 (Pubitemid 28160410)
17. T.M. Rezende, L.Q. Vieira, A.P. Sobrinho, R.R. Oliveira, M.A. Taubman, and T. Kawai The influence of mineral trioxide aggregate on adaptive immune responses to endodontic pathogens in mice J Endod 34 2008 1066 1071
18. M. Kajiya, K. Sato, and M.J. Silva Hydrogen from intestinal bacteria is protective for Concanavalin A-induced hepatitis Biochem Biophys Res Commun 386 2009 316 321
19. Y.Y. Kong, H. Yoshida, and I. Sarosi OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis Nature 397 1999 315 323
20. P.A. Farber, and S. Seltzer Endodontic microbiology. I. Etiology J Endod 14 1988 363 371
21. G. Sundqvist, E. Johansson, and U. Sjogren Prevalence of black-pigmented bacteroides species in root canal infections J Endod 15 1989 13 19 (Pubitemid 19041191)
22. M. Yoshida, H. Fukushima, K. Yamamoto, K. Ogawa, T. Toda, and H. Sagawa Correlation between clinical symptoms and microorganisms isolated from root canals of teeth with periapical pathosis J Endod 13 1987 24 28