Selective digestive decontamination and antibiotic resistance

The Lancet Infectious Diseases

Volumn 12, Issue 3, 2012, Pages 181-

  Bion, J ^a   Taylor, N ^b   Petros, A J ^c   Silvestri, L ^d   Van Saene, H K F ^b  

^a QUEEN ELIZABETH HOSPITAL   (United Kingdom)

^b UNIVERSITY OF LIVERPOOL   (United Kingdom)

^c GREAT ORMOND STREET HOSPITAL   (United Kingdom)

^d Unit of Anaesthesia and Intensive Care   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; POLYMYXIN; TOBRAMYCIN;

ANTIBIOTIC RESISTANCE; ASPERGILLUS FUMIGATUS; BACTERIAL OVERGROWTH; CRITICAL ILLNESS; DIGESTIVE SYSTEM; DISINFECTION; EUROPE; EVIDENCE BASED MEDICINE; HUMAN; INTENSIVE CARE UNIT; LETTER; PRIORITY JOURNAL; SELECTIVE DIGESTIVE DECONTAMINATION; VANCOMYCIN RESISTANT ENTEROCOCCUS;

EID: 84857184502     PISSN: 14733099     EISSN: 14744457     Source Type: Journal    
DOI: 10.1016/S1473-3099(11)70276-6     Document Type: Letter

References (6)

1. Vincent JL, Jacobs F Effect of selective decontamination on antibiotic resistance. Lancet Infect Dis 2011, 11:337-338.
2. de Smet AMGA, Kluytmans AJW, Blok HEM, et al. Selective digestive tract decontamination and selective oropharyngeal decontamination and antibiotic resistance in patients in intensive-care units: an open-label, clustered group-randomised, crossover study. Lancet Infect Dis 2011, 11:372-380.
3. van Saene HKF, Taylor N, Damjanovic V, et al. Microbial gut overgrowth guarantees increased spontaneous mutation leading to polyclonality and antibiotic resistance in the critically ill. Current Drug Targets 2008, 9:419-421.
4. Silvestri L, van Saene HKF Selective decontamination of the digestive tract does not increase resistance in critically ill patients: evidence from randomized controlled trials. Crit Care Med 2006, 34:2027-2030.
5. Heininger A, Meyer E, Schwab F, et al. Effects of long-term routine use of selective digestive decontamination on antimicrobial resistance. Intensive Care Med 2006, 32:1569-1576.
6. Hellinger WC, Yao JD, Alvarez S, et al. A randomized, prospective, double-blinded evaluation of selective bowel decontamination in liver transplantation. Transplantation 2002, 73:1904-1909.