Microbial gut overgrowth guarantees increased spontaneous mutation leading to polyclonality and antibiotic resistance in the critically ill

Current Drug Targets

Volumn 9, Issue 5, 2008, Pages 419-421

  van Saene, H K F ^a   Taylor, N ^a   Damjanovic, V ^a   Sarginson, R E ^b  

^a UNIVERSITY OF LIVERPOOL   (United Kingdom)

^b ALDER HEY CHILDREN'S NHS FOUNDATION TRUST   (United Kingdom)

Author keywords

Antimicrobial resistance; Gut overgrowth; Polyclonality; Spontaneous mutation

Indexed keywords

ANTIBIOTIC AGENT; ANTIINFECTIVE AGENT; HISTAMINE H2 RECEPTOR ANTAGONIST; LINEZOLID; OPIATE DERIVATIVE; VANCOMYCIN;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ANTIBIOTIC RESISTANCE; ARTIFICIAL VENTILATION; BACTERIAL MUTATION; BACTERIAL OVERGROWTH; CLONAL VARIATION; CRITICAL ILLNESS; CRITICALLY ILL PATIENT; ESCHERICHIA COLI; HOSPITAL INFECTION; HUMAN; INTENSIVE CARE; INTESTINE FLORA; NEUTROPENIA; NONHUMAN; PSEUDOMONAS AERUGINOSA; REVIEW; SPONTANEOUS MUTATION; VANCOMYCIN RESISTANT ENTEROCOCCUS; ARTICLE; BACTERIAL INFECTION; BACTERIUM; DIGESTIVE SYSTEM; DISEASE TRANSMISSION; GENE EXPRESSION REGULATION; GENETICS; GENOTYPE; GROWTH, DEVELOPMENT AND AGING; MICROBIOLOGY; MUTATION; PHENOTYPE;

ANTI-BACTERIAL AGENTS; BACTERIA; BACTERIAL INFECTIONS; CRITICAL ILLNESS; DIGESTIVE SYSTEM; DRUG RESISTANCE, BACTERIAL; GENE EXPRESSION REGULATION, BACTERIAL; GENOTYPE; HUMANS; MUTATION; PHENOTYPE;

EID: 44949221696     PISSN: 13894501     EISSN: None     Source Type: Journal    
DOI: 10.2174/138945008784221189     Document Type: Review

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