-
1
-
-
8244254377
-
Improvements in survival and clinical benefit with gemcitabine as first- line therapy for patients with advanced pancreas cancer: A randomized trial
-
Burris HA III, Moore MJ, Andersen J, et al: Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: a randomized trial. J Clin Oncol 15: 2403-2413, 1997. (Pubitemid 27251144)
-
(1997)
Journal of Clinical Oncology
, vol.15
, Issue.6
, pp. 2403-2413
-
-
Burris III, H.A.1
Moore, M.J.2
Andersen, J.3
Green, M.R.4
Rothenberg, M.L.5
Modiano, M.R.6
Cripps, M.C.7
Portenoy, R.K.8
Storniolo, A.M.9
Tarassoff, P.10
Nelson, R.11
Dorr, F.A.12
Stephens, C.D.13
Von Hoff, D.D.14
-
2
-
-
77951755278
-
Pancreatic cancer
-
Hidalgo M: Pancreatic cancer. N Engl J Med 362: 1605-1617, 2010.
-
(2010)
N Engl J Med
, vol.362
, pp. 1605-1617
-
-
Hidalgo, M.1
-
3
-
-
78651108985
-
Pancreatic cancer: Understanding and overcoming chemoresistance
-
Wang Z, Li Y, Ahmad A, Banerjee S, Azmi AS, Kong D and Sarkar FH: Pancreatic cancer: understanding and overcoming chemoresistance. Nat Rev Gastroenterol Hepatol 8: 27-33, 2011.
-
(2011)
Nat Rev Gastroenterol Hepatol
, vol.8
, pp. 27-33
-
-
Wang, Z.1
Li, Y.2
Ahmad, A.3
Banerjee, S.4
Azmi, A.S.5
Kong, D.6
Sarkar, F.H.7
-
4
-
-
0031671246
-
Differentiation and reversal of malignant changes in colon cancer through PPARγ
-
DOI 10.1038/2030
-
Sarraf P, Mueller E, Jones D, et al: Differentiation and reversal of malignant changes in colon cancer through PPARγ. Nat Med 4: 1046-1052, 1998. (Pubitemid 28417337)
-
(1998)
Nature Medicine
, vol.4
, Issue.9
, pp. 1046-1052
-
-
Sarraf, P.1
Mueller, E.2
Jones, D.3
King, F.J.4
DeAngelo, D.J.5
Partridge, J.B.6
Holden, S.A.7
Chen, L.B.8
Singer, S.9
Fletcher, C.10
Spiegelman, B.M.11
-
6
-
-
0035929351
-
Peroxisome proliferator-activated receptor γ induces pancreatic cancer cell apoptosis
-
DOI 10.1006/bbrc.2001.5619
-
Eibl G, Wente MN, Reber HA and Hines OJ: Peroxisome proliferator- activated receptor γ induces pancreatic cancer cell apoptosis. Biochem Biophys Res Commun 287: 522-529, 2001. (Pubitemid 32917630)
-
(2001)
Biochemical and Biophysical Research Communications
, vol.287
, Issue.2
, pp. 522-529
-
-
Eibl, G.1
Wente, M.N.2
Reber, H.A.3
Hines, O.J.4
-
7
-
-
0035035402
-
INK4cin troglitazone-induced cell-cycle arrest in human hepatoma cell lines
-
INK4c in troglitazone-induced cell-cycle arrest in human hepatoma cell lines. Hepatology 33: 1087-1097, 2001.
-
(2001)
Hepatology
, vol.33
, pp. 1087-1097
-
-
Koga, H.1
Sakisaka, S.2
Harada, M.3
-
8
-
-
33751303104
-
Peroxisome proliferator-activated receptor γ is highly expressed in pancreatic cancer and is associated with shorter overall survival times
-
DOI 10.1158/1078-0432.CCR-06-0834
-
Kristiansen G, Jacob J, Buckendahl AC, et al: Peroxisome proliferator- activated receptor γ is highly expressed in pancreatic cancer and is associated with shorter overall survival times. Clin Cancer Res 12: 6444-6451, 2006. (Pubitemid 44799717)
-
(2006)
Clinical Cancer Research
, vol.12
, Issue.21
, pp. 6444-6451
-
-
Kristiansen, G.1
Jacob, J.2
Buckendahl, A.-C.3
Grutzmann, R.4
Alldinger, I.5
Sipos, B.6
Kloppel, G.7
Bahra, M.8
Langrehr, J.M.9
Neuhaus, P.10
Dietel, M.11
Pilarsky, C.12
-
9
-
-
0032746173
-
A novel therapy for colitis utilizing PPAR-γ ligands to inhibit the epithelial inflammatory response
-
Su CG, Wen X, Bailey ST, et al: A novel therapy for colitis utilizing PPAR-γ ligands to inhibit the epithelial inflammatory response. J Clin Invest 104: 383-389, 1999. (Pubitemid 29534322)
-
(1999)
Journal of Clinical Investigation
, vol.104
, Issue.4
, pp. 383-389
-
-
Su, C.G.1
Wen, X.2
Bailey, S.T.3
Jiang, W.4
Rangwala, S.M.5
Keilbaugh, S.A.6
Flanigan, A.7
Murthy, S.8
Lazar, M.A.9
Wu, G.D.10
-
10
-
-
16844366650
-
Nuclear factor-kappaB inhibitors as sensitizers to anticancer drugs
-
DOI 10.1038/nrc1588
-
Nakanishi C and Toi M: Nuclear factor-κB inhibitors as sensitizers to anticancer drugs. Nat Rev Cancer 5: 297-309, 2005. (Pubitemid 40488635)
-
(2005)
Nature Reviews Cancer
, vol.5
, Issue.4
, pp. 297-309
-
-
Nakanishi, C.1
Toi, M.2
-
11
-
-
0036900873
-
The retinoblastoma-histone deacetylase 3 complex inhibits PPARγ and adipocyte differentiation
-
DOI 10.1016/S1534-5807(02)00360-X
-
Fajas L, Egler V, Reiter R, et al: The retinoblastoma-histone deacetylase 3 complex inhibits PPARγ and adipocyte differentiation. Dev Cell 3: 903-910, 2002. (Pubitemid 35460789)
-
(2002)
Developmental Cell
, vol.3
, Issue.6
, pp. 903-910
-
-
Fajas, L.1
Egler, V.2
Reiter, R.3
Hansen, J.4
Kristiansen, K.5
Debril, M.-B.6
Mirard, S.7
Auwerx, J.8
-
12
-
-
33749626553
-
Peroxisome proliferator-activated receptor γ regulates E-cadherin expression and inhibits growth and invasion of prostate cancer
-
DOI 10.1128/MCB.00605-06
-
Annicotte JS, Iankova I, Miard S, et al: Peroxisome proliferator- activated receptor γ regulates E-cadherin expression and inhibits growth and invasion of prostate cancer. Mol Cell Biol 26: 7561-7574, 2006. (Pubitemid 44547706)
-
(2006)
Molecular and Cellular Biology
, vol.26
, Issue.20
, pp. 7561-7574
-
-
Annicotte, J.-S.1
Iankova, I.2
Miard, S.3
Fritz, V.4
Sarruf, D.5
Abella, A.6
Berthe, M.-L.7
Noel, D.8
Pillon, A.9
Iborra, F.10
Dubus, P.11
Maudelonde, T.12
Culine, S.13
Fajas, L.14
-
13
-
-
0038713185
-
Kip1-associated cell-cycle arrest through down-regulating Skp2 in human hepatoma cells
-
Kip1-associated cell-cycle arrest through down-regulating Skp2 in human hepatoma cells. Hepatology 37: 1086-1096, 2003.
-
(2003)
Hepatology
, vol.37
, pp. 1086-1096
-
-
Koga, H.1
Harada, M.2
Ohtsubo, M.3
-
14
-
-
0034721937
-
Ligand type-specific interactions of peroxisome proliferator-activated receptor γ with transcriptional coactivators
-
Kodera Y, Takeyama K, Murayama A, Suzawa M, Masuhiro Y and Kato S: Ligand type-specific interactions of peroxisome proliferator-activated receptor γ with transcriptional coactivators. J Biol Chem 275: 33201-33204, 2000.
-
(2000)
J Biol Chem
, vol.275
, pp. 33201-33204
-
-
Kodera, Y.1
Takeyama, K.2
Murayama, A.3
Suzawa, M.4
Masuhiro, Y.5
Kato, S.6
-
15
-
-
77958581453
-
Identification of up- and down-regulated proteins in gemcitabine- resistant pancreatic cancer cells using two-dimensional gel electrophoresis and mass spectrometry
-
Kuramitsu Y, Taba K, Ryozawa S, et al: Identification of up- and down-regulated proteins in gemcitabine-resistant pancreatic cancer cells using two-dimensional gel electrophoresis and mass spectrometry. Anticancer Res 30: 3367-3372, 2010.
-
(2010)
Anticancer Res
, vol.30
, pp. 3367-3372
-
-
Kuramitsu, Y.1
Taba, K.2
Ryozawa, S.3
-
16
-
-
79960209335
-
Randomized phase III study of gemcitabine plus S-1 (GS) versus S-1 versus gemcitabine (GEM) in unresectable advanced pancreatic cancer (PC) in Japan and Taiwan: GEST study
-
GEST study group. abstr 4007
-
Ioka T, Ikeda M, Ohkawa S, et al: GEST study group. Randomized phase III study of gemcitabine plus S-1 (GS) versus S-1 versus gemcitabine (GEM) in unresectable advanced pancreatic cancer (PC) in Japan and Taiwan: GEST study. J Clin Oncol 29: (suppl) abstr 4007, 2011.
-
(2011)
J Clin Oncol
, vol.29
, Issue.SUPPL.
-
-
Ioka, T.1
Ikeda, M.2
Ohkawa, S.3
-
17
-
-
79958273231
-
Overcoming drug resistance in pancreatic cancer
-
Long J, Zhang Y, Yu X, et al: Overcoming drug resistance in pancreatic cancer. Expert Opin Ther Targets 15: 817-828, 2011.
-
(2011)
Expert Opin Ther Targets
, vol.15
, pp. 817-828
-
-
Long, J.1
Zhang, Y.2
Yu, X.3
-
18
-
-
79955921754
-
FOLFIRINOX versus gemcitabine for metastatic pancreatic cancer
-
Groupe Tumeurs Digestives of Unicancer; PRODIGE Intergroup
-
Conroy T, Desseigne F, Ychou M, et al: Groupe Tumeurs Digestives of Unicancer; PRODIGE Intergroup. FOLFIRINOX versus gemcitabine for metastatic pancreatic cancer. N Engl J Med 364: 1817-1825, 2011.
-
(2011)
N Engl J Med
, vol.364
, pp. 1817-1825
-
-
Conroy, T.1
Desseigne, F.2
Ychou, M.3
-
19
-
-
34249933404
-
Erlotinib plus gemcitabine compared with gemcitabine alone in patients with advanced pancreatic cancer: A phase III trial of the National Cancer Institute of Canada Clinical Trials Group
-
DOI 10.1200/JCO.2006.07.9525
-
Moore MJ, Goldstein D, Hamm J, et al: National Cancer Institute of Canada Clinical Trials Group. Erlotinib plus gemcitabine compared with gemcitabine alone in patients with advanced pancreatic cancer: a phase III trial of the National Cancer Institute of Canada Clinical Trials Group. J Clin Oncol 25: 1960-1966, 2007. (Pubitemid 46972777)
-
(2007)
Journal of Clinical Oncology
, vol.25
, Issue.15
, pp. 1960-1966
-
-
Moore, M.J.1
Goldstein, D.2
Hamm, J.3
Figer, A.4
Hecht, J.R.5
Gallinger, S.6
Au, H.J.7
Murawa, P.8
Walde, D.9
Wolff, R.A.10
Campos, D.11
Lim, R.12
Ding, K.13
Clark, G.14
Voskoglou-Nomikos, T.15
Ptasynski, M.16
Parulekar, W.17
-
20
-
-
67650924582
-
Pancreatic cancer: Molecular pathogenesis and new therapeutic targets
-
Wong HH and Lemoine NR: Pancreatic cancer: molecular pathogenesis and new therapeutic targets. Nat Rev Gastroenterol Hepatol 6: 412-422, 2009.
-
(2009)
Nat Rev Gastroenterol Hepatol
, vol.6
, pp. 412-422
-
-
Wong, H.H.1
Lemoine, N.R.2
-
21
-
-
77955914277
-
Phase III study comparing gemcitabine plus cetuximab versus gemcitabine in patients with advanced pancreatic adenocarcinoma: Southwest Oncology Group-directed intergroup trial S0205
-
Philip PA, Benedetti J, Corless CL, et al: Phase III study comparing gemcitabine plus cetuximab versus gemcitabine in patients with advanced pancreatic adenocarcinoma: Southwest Oncology Group-directed intergroup trial S0205. J Clin Oncol 28: 3605-3610, 2010.
-
(2010)
J Clin Oncol
, vol.28
, pp. 3605-3610
-
-
Philip, P.A.1
Benedetti, J.2
Corless, C.L.3
-
22
-
-
79956094173
-
Does erlotinib restore chemosensitivity to chemotherapy in pancreatic cancer? A case series
-
Saif MW: Does erlotinib restore chemosensitivity to chemotherapy in pancreatic cancer? A case series. Anticancer Res 31: 1039-1042, 2011.
-
(2011)
Anticancer Res
, vol.31
, pp. 1039-1042
-
-
Saif, M.W.1
-
23
-
-
67649637824
-
Sulforaphane targets pancreatic tumour-initiating cells by NF-κB-induced antiapoptotic signalling
-
Kallifatidis G, Rausch V, Baumann B, et al: Sulforaphane targets pancreatic tumour-initiating cells by NF-κB-induced antiapoptotic signalling. Gut 58: 949-963, 2009.
-
(2009)
Gut
, vol.58
, pp. 949-963
-
-
Kallifatidis, G.1
Rausch, V.2
Baumann, B.3
-
24
-
-
78650743255
-
Restoring sensitivity to oxaliplatin by a novel approach in gemcitabine-resistant pancreatic cancer cells in vitro and in vivo
-
Banerjee S, Kong D, Azmi AS, et al: Restoring sensitivity to oxaliplatin by a novel approach in gemcitabine-resistant pancreatic cancer cells in vitro and in vivo. Int J Cancer 128: 1240-1250, 2011.
-
(2011)
Int J Cancer
, vol.128
, pp. 1240-1250
-
-
Banerjee, S.1
Kong, D.2
Azmi, A.S.3
-
25
-
-
58149359830
-
Nuclear factor-κB p65/relA silencing induces apoptosis and increases gemcitabine effectiveness in a subset of pancreatic cancer cells
-
Pan X, Arumugam T, Yamamoto T, et al: Nuclear factor-κB p65/relA silencing induces apoptosis and increases gemcitabine effectiveness in a subset of pancreatic cancer cells. Clin Cancer Res 14: 8143-8151, 2008.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 8143-8151
-
-
Pan, X.1
Arumugam, T.2
Yamamoto, T.3
-
26
-
-
78651355589
-
Complexities of obesity and diabetes mellitus with the development and progression of pancreatic cancer
-
Bao B, Wang Z, Li Y, et al: Complexities of obesity and diabetes mellitus with the development and progression of pancreatic cancer. Biochim Biophys Acta 1815: 135-146, 2011.
-
(2011)
Biochim Biophys Acta
, vol.1815
, pp. 135-146
-
-
Bao, B.1
Wang, Z.2
Li, Y.3
-
27
-
-
66749130761
-
Glycogen synthase kinase-3 inhibition disrupts nuclear factor-κB activity in pancreatic cancer, but fails to sensitize to gemcitabine chemotherapy
-
Mamaghani S, Patel S and Hedley DW: Glycogen synthase kinase-3 inhibition disrupts nuclear factor-κB activity in pancreatic cancer, but fails to sensitize to gemcitabine chemotherapy. BMC Cancer 9: 132, 2009.
-
(2009)
BMC Cancer
, vol.9
, pp. 132
-
-
Mamaghani, S.1
Patel, S.2
Hedley, D.W.3
|