Effects of different degrees of insulin sensitivity on endothelial function in obese patients

Arquivos Brasileiros de Cardiologia

Volumn 98, Issue 1, 2012, Pages 45-50

  Galvão, Roberto ^a   Plavnik, Frida Liane ^a   Ribeiro, Fernando Flexa ^a   Ajzen, Sérgio Aron ^a   Christofalo, Dejaldo M de J ^a   Kohlmann, Osvaldo ^a  

^a FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Diabetes mellitus; Endothelium; Hypertension; Insulin resistance; Obesity

Indexed keywords

TRIACYLGLYCEROL;

ADULT; AGED; ANTHROPOMETRY; ARTICLE; BLOOD PRESSURE; BLOOD PRESSURE MONITORING; BODY HEIGHT; BODY MASS; BODY WEIGHT; CARDIOVASCULAR DISEASE; CELL FUNCTION; CLINICAL ARTICLE; CONTROLLED STUDY; ENDOTHELIUM CELL; FEMALE; HUMAN; INSULIN RESISTANCE; INSULIN SENSITIVITY; LABORATORY TEST; MALE; METABOLIC SYNDROME X; OBESITY; OUTCOME ASSESSMENT; ULTRASOUND; VASODILATATION; WAIST CIRCUMFERENCE;

EID: 84857153823     PISSN: 0066782X     EISSN: 16784170     Source Type: Journal    
DOI: 10.1590/S0066-782X2011005000119     Document Type: Article

References (34)

1. Pi-Sunyer FX The obesity epidemic: pathophysiology and consequences of obesity. Obes Res. 2002;10(Suppl 2):97S-104S.
2. Arcaro G, Zamboni M, Rossi L, Turcato E, Covi G, Armellini F, et al. Body fat distribution predicts the degree of endothelial dysfunction in uncomplicated obesity. Int J Obes Relat Metab Disord. 1999;23(9):936-42.
3. Williams IL, Chowienczyk PJ, Wheatcroft SB, Patel A, Sherwood R, Momin A, et al. Effect of fat distribution on endothelial-dependent and endothelial-independent vasodilatation in healthy humans. Diabetes Obes Metab. 2006;8(3):296-301.
4. Giorgino F, Laviola L, Eriksson JW. Regional differences of insulin action in adipose tissue: insights from in vivo and in vitro studies. Acta Physiol Scand. 2005;183(1):13-30.
5. Lima NK, Abbasi F, Lamendola C, Reaven GM. Prevalence of insulin resistance and related risk factors for cardiovascular disease in patients with essential hypertension. Am J Hypertens. 2009;22(1):106-11.
6. Sjöholm A, Nyström T. Endothelial inflammation in insulin resistance. Lancet. 2005;365(9459):610-2.
7. Despres JP, Lamarche B, Mauriege P, Cantin B, Dagenais GR, Moorjani S, et al. Hyperinsulinemia as an independent risk factor for ischemic heart disease. N Engl J Med. 1996;334(15):952-7.
8. Arcaro G, Cretti A, Balzano S, Lechi A, Muggeo M, Bonora E, et al. Insulin causes endothelial dysfunction in humans: sites and mechanisms. Circulation. 2002;105(5):576-82
9. Steinberg HO, Chaker H, Leaming R, Johnson A, Brechtel G, Baron AD. Obesity/insulin resistance is associated with endothelial dysfunction: implications for the syndrome of insulin resistance. J Clin Invest. 1996;97(11):2601-10.
10. Perticone F, Sciacqua A, Maio R, Perticone M, Galiano Leone G, Bruni R, et al. Endothelial dysfunction, ADMA and insulin resistance in essential hypertension. Int J Cardiol. 2010;142(3):236-41
11. Giannarelli C, De Negri F, Virdis A, Ghiadoni L, Cipriano A, Magagna A, et al. Nitric oxide modulates tissue plasminogen activator release in normotensive subjects and hypertensive patients. Hypertension. 2007;49(4):878-84.
12. Melikian N, Chowienczyk P, Maccarthy PA, Williams IL, Wheatcroft SB, Sherwood R, et al. Determinants of endothelial function in asymptomatic subjects with and without the metabolic syndrome. Atherosclerosis. 2008;197(1):375-82.
13. National Heart, Lung, and Blood Institute in cooperation with The National Institute of Diabetes and Digestive and Kidney Disease. Clinical guidelines on the identification, evaluation, and treatment overweight and obesity in adults. The Evidence Report NIH Publication. 1998;98-4083.
14. Mion Jr D, Kohlmann Jr O, Machado CA, Amodeo C, Gomes MAN, Praxedes JN, et al. Sociedade Brasileira de Cardiologia, Sociedade Brasileira de Hipertensão, Sociedade Brasileira de Nefrologia. V Diretrizes brasileiras de hipertensão arterial. Rev bras hipertens. 2006;13(4):260-312.
15. Pickering TG, Hall JE, Appel LJ, Falkner BE, Graves J, Hill MN, et al. Recommendations for blood pressure measurement in humans and experimental animals: part 1: blood pressure measurement in humans: a statement for professionals from the Subcommittee of Professional and Public Education of the American Heart Association Council on High Blood Pressure Research. Circulation. 2005;111(5):697-716.
16. Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia. 1985;28(7):412-9.
17. National Heart, Lung, and Blood Institute; National Institutes of Health. Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). NIH Publication. 2002;02-5215.
18. Celermajer DS, Sorensen KE, Gooch VM, Spiegelhalter DJ, Miller OI, Sullivan ID, et al. Non-invasive detection of endothelial dysfunction in children and adults at risk of atherosclerosis. Lancet. 1992;340(8828):1111-5.
19. Anderson TJ, Gerhard MD, Meredith IT, Charbonneau F, Delagrange D, Creager MA, et al. Systemic nature of endothelial dysfunction in atherosclerosis. Am J Cardiol. 1995;75(6):71B-74B.
20. Ford ES, Giles WH, Dietz WH. Prevalence of the metabolic syndrome among US adults: findings from the third National Health and Nutrition Examination Survey. JAMA. 2002;287(3):356-9.
21. Plavnik FL, Ajzen SA, Christofalo DM, Barbosa CS, Kohlmann O Jr. Endothelial function in normotensive and high-normal hypertensive subjects. J Hum Hypertens. 2007;21(6):467-72.
22. Oliveira EP, Souza MLA, Lima MDA. Índice HOMA (homeostasis model assessment) na prática clínica: uma revisão. J Bras Patol Med Lab. 2005;41(4):237-43.
23. Hanley AJ, Williams K, Stern MP, Haffner SM. Homeostasis model assessment of insulin resistance in relation to the incidence of cardiovascular disease: The San Antonio Heart Study. Diabetes Care. 2002;25(7):1177-84.
24. Geloneze B, Repetto EM, Geloneze SR, Tambascia MA, Ermetice MN. The threshold value for insulin resistance (HOMA-IR) in an admixtured population IR in the Brazilian Metabolic Syndrome Study. Diabetes Res Clin Pract. 2006;72(2):219-20.
25. Balletshofer BM, Rittig K, Enderle MD, Volk A, Maerker E, Jacob S, et al. Endothelial dysfunction is detectable in young normotensive first-degree relatives of subjects with type 2 diabetes in association with insulin resistance. Circulation. 2000;101(15):1780-4.
26. Kuboki K, Jiang ZY, Takahara N, Ha SW, Igarashi M, Yamauchi T, et al. Regulation of endothelial constitutive nitric oxide synthase gene expression in endothelial cells and in vivo: a specific vascular action of insulin. Circulation. 2000;101(6):676-81.
27. Kim JA, Montagnani M, Koh KK, Quon MJ. Reciprocal relationships between insulin resistance and endothelial dysfunction: molecular and pathophysiological mechanisms. Circulation. 2006;113(15):1888-904.
28. Winkler G, Lakatos P, Salamon F, Nagy Z, Speer G, Kovács M, et al. Elevated serum TNF-alpha level as a link between endothelial dysfunction and insulin resistance in normotensive obese patients. Diabet Med. 1999;16(3):207-11.
29. Bonora E, Targher G, Alberiche M, Bonadonna RC, Saggiani F, Zenere MB, et al. Homeostasis model assessment closely mirrors the glucose clamp technique in the assessment of insulin sensitivity: studies in subjects with various degrees of glucose tolerance and insulin sensitivity. Diabetes Care. 2002;25(3):626-40.
30. Lamarche B, Tchernof A, Mauriège P, Cantin B, Dagenais GR, Lupien PJ, et al. Fasting insulin and apolipoprotein B levels and low-density lipoprotein particle size as risk factors for ischemic heart disease. JAMA. 1998;279(24):1955-61.
31. Lundman P, Eriksson MJ, Silveira A, Hansson LO, Pernow J, Ericsson CG, et al. Relation of hypertriglyceridemia to plasma concentrations of biochemical markers of inflammation and endothelial activation (C-reactive protein, interleukin-6, soluble adhesion molecules, von Willebrand factor, and endothelin-1). Am J Cardiol. 2003;91(9):1128-31.
32. Carvalho MH, Colaço AL, Fortes ZB. Citocinas, disfunção endotelial e resistência à insulina. Arq Bras Endocrinol Metab. 2006;50(2):304-12.
33. Rapp RJ. Hypertriglyceridemia: a review beyond low-density lipoprotein. Cardiol Rev. 2002;10(3):163-72.
34. Lin CY, Chen MF, Lin LY, Liau CS, Lee YT, Su TC. Insulin resistance is the major determinant for microalbuminuria in severe hypertriglyceridemia: implication for high-risk stratification. Intern Med. 2008;47(12):1091-7.