Facilitating the use of counter-current chromatography in pharmaceutical purification through use of organic solvent nanofiltration

Journal of Chromatography A

Volumn 1229, Issue , 2012, Pages 156-163

  Rundquist, Elin ^a,b   Pink, Christopher ^a   Vilminot, Elsa ^a   Livingston, Andrew ^b  

^a GLAXOSMITHKLINE   (United Kingdom)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

Counter current chromatography; Organic solvent nanofiltration; Pharmaceutical processing; Solvent exchange; Solvent recovery

Indexed keywords

ACTIVE PHARMACEUTICAL INGREDIENTS; COUNTERCURRENT CHROMATOGRAPHY; INDUSTRIAL PROCESSS; MOBILE PHASE; ORGANIC SOLVENT NANOFILTRATION; PHARMACEUTICAL PROCESS; RECOVERED SOLVENT; SOLVENT EXCHANGE; SOLVENT RECOVERY; WASTE STREAM;

CHROMATOGRAPHY; IMPURITIES; NANOFILTRATION; ORGANIC SOLVENTS;

SOLVENTS;

ORGANIC SOLVENT;

ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; COUNTER CURRENT CHROMATOGRAPHY; CRYSTALLIZATION; DEGRADATION; DRUG IMPURITY; DRUG PURIFICATION; MOLECULAR WEIGHT; NANOFILTRATION; PARTICLE SIZE; PHASE SEPARATION; PRIORITY JOURNAL; PRODUCT RECOVERY; SOLVENT EFFECT; SOLVENT EXTRACTION;

COUNTERCURRENT DISTRIBUTION; FILTRATION; MEMBRANES, ARTIFICIAL; NANOTECHNOLOGY; ORGANIC CHEMICALS; PHARMACEUTICAL PREPARATIONS; SOLVENTS; TECHNOLOGY, PHARMACEUTICAL;

EID: 84857141621     PISSN: 00219673     EISSN: 18733778     Source Type: Journal    
DOI: 10.1016/j.chroma.2012.01.021     Document Type: Article

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