Full-length myosin Va exhibits altered gating during processive movement on actin

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 5, 2012, Pages

  Armstrong, Jessica M ^a   Krementsova, Elena ^a   Michalek, Arthur J ^a   Heaslip, Aoife T ^a   Nelson, Shane R ^a   Trybus, Kathleen M ^a   Warshaw, David M ^a  

^a UNIVERSITY OF VERMONT   (United States)

Author keywords

Molecular motors; Regulation; Single molecules

Indexed keywords

ACTIN; ADENOSINE TRIPHOSPHATE MAGNESIUM; MYOSIN VA; QUANTUM DOT; SODIUM CHLORIDE;

ARTICLE; IONIC STRENGTH; MOLECULE; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN INTERACTION;

ACTINS; ANIMALS; MICE; MYOSIN HEAVY CHAINS; MYOSIN TYPE V; OSMOLAR CONCENTRATION; ULTRACENTRIFUGATION;

EID: 84857136367     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1109709109     Document Type: Article

References (38)

1. Yildiz A, et al. (2003) Myosin V walks hand-over-hand: Single fluorophore imaging with 1.5-nm localization. Science 300:2061-2065. (Pubitemid 36760126)
2. Warshaw DM, et al. (2005) Differential labeling of myosin V heads with quantum dots allows direct visualization of hand-over-hand processivity. Biophys J 88:L30-32. (Pubitemid 40586558)
3. Trybus KM (2008) Myosin V from head to tail. Cell Mol Life Sci 65:1378-1389.
4. 2+-induced activation of ATPase activity of myosin Va is accompanied with a large conformational change. Biochem Biophys Res Commun 315:538-545.
5. Lu H, Krementsova EB, Trybus KM (2006) Regulation of myosin V processivity by calcium at the single molecule level. J Biol Chem 281:31987-31994. (Pubitemid 46041460)
6. Wang F, et al. (2004) Regulated conformation of myosin V. J Biol Chem 279:2333-2336. (Pubitemid 38114214)
7. Liu J, Taylor DW, Krementsova EB, Trybus KM, Taylor KA (2006) Three-dimensional structure of the myosin V inhibited state by cryoelectron tomography. Nature 442:208-211. (Pubitemid 44086568)
8. Thirumurugan K, Sakamoto T, Hammer JA, 3rd, Sellers JR, Knight PJ (2006) The cargobinding domain regulates structure and activity of myosin 5. Nature 442:212-215. (Pubitemid 44086569)
9. Olivares AO, Chang W, Mooseker MS, Hackney DD, De La Cruz EM (2006) The tail domain of myosin Va modulates actin binding to one head. J Biol Chem 281:31326-31336. (Pubitemid 46041397)
10. Sato O, Li XD, Ikebe M (2007) Myosin Va becomes a low duty ratio motor in the inhibited form. J Biol Chem 282:13228-13239. (Pubitemid 47100520)
11. Trybus KM, et al. (2007) Effect of calcium on calmodulin bound to the IQ motifs of myosin V. J Biol Chem 282:23316-23325. (Pubitemid 47311916)
12. Wang Z, et al. (2008) Myosin Vb mobilizes recycling endosomes and AMPA receptors for postsynaptic plasticity. Cell 135:535-548.
13. Wu X, Sakamoto T, Zhang F, Sellers JR, Hammer JA, 3rd (2006) In vitro reconstitution of a transport complex containing Rab27a, melanophilin and myosin Va. FEBS Lett 580:5863-5868. (Pubitemid 44584286)
14. Sakamoto T, Amitani I, Yokota E, Ando T (2000) Direct observation of processive movement by individual myosin V molecules. Biochem Biophys Res Commun 272:586-590. (Pubitemid 30444660)
15. Forkey JN, Quinlan ME, Shaw MA, Corrie JE, Goldman YE (2003) Three-dimensional structural dynamics of myosin V by single-molecule fluorescence polarization. Nature 422:399-404. (Pubitemid 36411387)
16. Huang JD, et al. (1998) Molecular genetic dissection of mouse unconventional myosin- VA: Tail region mutations. Genetics 148:1963-1972.
17. Lambert J, Naeyaert JM, Callens T, De Paepe A, Messiaen L (1998) Human myosin V gene produces different transcripts in a cell type-specific manner. Biochem Biophys Res Commun 252:329-333. (Pubitemid 28542886)
18. Nagashima K, et al. (2002) Melanophilin directly links Rab27a and myosin Va through its distinct coiled-coil regions. FEBS Lett 517:233-238. (Pubitemid 34327666)
19. Roland JT, Lapierre LA, Goldenring JR (2009) Alternative splicing in class V myosins determines association with Rab10. J Biol Chem 284:1213-1223.
20. Seperack PK, Mercer JA, Strobel MC, Copeland NG, Jenkins NA (1995) Retroviral sequences located within an intron of the dilute gene alter dilute expression in a tissue-specific manner. EMBO J 14:2326-2332.
21. Wagner W, Fodor E, Ginsburg A, Hammer JA, 3rd (2006) The binding of DYNLL2 to myosin Va requires alternatively spliced exon B and stabilizes a portion of the myosin's coiled-coil domain. Biochemistry 45:11564-11577. (Pubitemid 44454004)
22. Wu XS, et al. (2002) Identification of an organelle receptor for myosin-Va. Nat Cell Biol 4:271-278. (Pubitemid 34308852)
23. Walker ML, et al. (2000) Two-headed binding of a processive myosin to F-actin. Nature 405:804-807. (Pubitemid 30407854)
24. Yengo CM, De la Cruz EM, Safer D, Ostap EM, Sweeney HL (2002) Kinetic characterization of the weak binding states of myosin V. Biochemistry 41:8508-8517. (Pubitemid 34705506)
25. Baker JE, et al. (2004) Myosin V processivity: multiple kinetic pathways for head-to-head coordination. Proc Natl Acad Sci USA 101:5542-5546. (Pubitemid 38481193)
26. Cheney RE, et al. (1993) Brain myosin-V is a two-headed unconventional myosin with motor activity. Cell 75:13-23. (Pubitemid 23306017)
27. Snyder GE, Sakamoto T, Hammer JA, 3rd, Sellers JR, Selvin PR (2004) Nanometer localization of single green fluorescent proteins: Evidence that myosin V walks hand-over-hand via telemark configuration. Biophys J 87:1776-1783. (Pubitemid 39167033)
28. Kad NM, Trybus KM, Warshaw DM (2008) Load and Pi control flux through the branched kinetic cycle of myosin V. J Biol Chem 283:17477-17484.
29. Nishikawa S, et al. (2010) Switch between large hand-over-hand and small inchworm-like steps in myosin VI. Cell 142:879-888.
30. Krementsov DN, Krementsova EB, Trybus KM (2004) Myosin V: regulation by calcium, calmodulin, and the tail domain. J Cell Biol 164:877-886. (Pubitemid 38366899)
31. Veigel C, Schmitz S, Wang F, Sellers JR (2005) Load-dependent kinetics of myosin-V can explain its high processivity. Nat Cell Biol 7:861-869. (Pubitemid 41486286)
32. Hackney DD, Stock MF (2000) Kinesin's IAK tail domain inhibits initial microtubule-stimulated ADP release. Nat Cell Biol 2:257-260.
33. Coy DL, Hancock WO, Wagenbach M, Howard J (1999) Kinesin's tail domain is an inhibitory regulator of the motor domain. Nat Cell Biol 1:288-292. (Pubitemid 129495779)
34. Ali MY, Lu H, Bookwalter CS, Warshaw DM, Trybus KM (2008) Myosin V and Kinesin act as tethers to enhance each others' processivity. Proc Natl Acad Sci USA 105:4691-4696. (Pubitemid 351753808)
35. Nelson SR, Ali MY, Trybus KM, Warshaw DM (2009) Random walk of processive, quantum dot-labeled myosin Va molecules within the actin cortex of COS-7 cells. Biophys J 97:509-518.
36. Philo JS (2000) A method for directly fitting the time derivative of sedimentation velocity data and an alternative algorithm for calculating sedimentation coefficient distribution functions. Anal Biochem 279:151-163.
37. Sage D, Neumann FR, Hediger F, Gasser SM, Unser M (2005) Automatic tracking of individual fluorescence particles: application to the study of chromosome dynamics. IEEE Trans Image Process 14:1372-1383. (Pubitemid 41430899)
38. Kerssemakers JW, et al. (2006) Assembly dynamics of microtubules at molecular resolution. Nature 442:709-712. (Pubitemid 44215328)