-
1
-
-
0034958947
-
Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care
-
Angus DC, et al. 2001. Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care. Crit. Care Med. 29:1303-1310.
-
(2001)
Crit. Care Med.
, vol.29
, pp. 1303-1310
-
-
Angus, D.C.1
-
2
-
-
34250700118
-
Factor Xa or thrombin: is factor Xa a better target?
-
Ansell J. 2007. Factor Xa or thrombin: is factor Xa a better target? J. Thromb. Haemost. 5(Suppl. 1):60-64.
-
(2007)
J. Thromb. Haemost.
, vol.5
, Issue.1
, pp. 60-64
-
-
Ansell, J.1
-
4
-
-
0035826096
-
Efficacy and safety of recombinant human activated protein C for severe sepsis
-
Bernard GR, et al. 2001. Efficacy and safety of recombinant human activated protein C for severe sepsis. N. Engl. J. Med. 344:699-709.
-
(2001)
N. Engl. J. Med.
, vol.344
, pp. 699-709
-
-
Bernard, G.R.1
-
5
-
-
0026710191
-
Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP/SCCM Consensus Conference Committee. American College of Chest Physicians/ Society of Critical Care Medicine
-
Bone RC, et al. 1992. Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP/SCCM Consensus Conference Committee. American College of Chest Physicians/ Society of Critical Care Medicine. Chest 101:1644-1655.
-
(1992)
Chest
, vol.101
, pp. 1644-1655
-
-
Bone, R.C.1
-
6
-
-
78149428887
-
A role for factor XIIa-mediated factor XI activation in thrombus formation in vivo
-
Cheng Q, et al. 2010. A role for factor XIIa-mediated factor XI activation in thrombus formation in vivo. Blood 116:3981-3989.
-
(2010)
Blood
, vol.116
, pp. 3981-3989
-
-
Cheng, Q.1
-
7
-
-
79953292076
-
Cecal ligation and puncture: the gold standard model for polymicrobial sepsis?
-
Dejager L, Pinheiro I, Dejonckheere E, Libert C. 2011. Cecal ligation and puncture: the gold standard model for polymicrobial sepsis? Trends Microbiol. 19:198-208.
-
(2011)
Trends Microbiol
, vol.19
, pp. 198-208
-
-
Dejager, L.1
Pinheiro, I.2
Dejonckheere, E.3
Libert, C.4
-
8
-
-
58849093274
-
Animal models of sepsis: why does preclinical efficacy fail to translate to the clinical setting?
-
Dyson A, Singer M. 2009. Animal models of sepsis: why does preclinical efficacy fail to translate to the clinical setting? Crit. Care Med. 37:S30-S37.
-
(2009)
Crit. Care Med.
, vol.37
-
-
Dyson, A.1
Singer, M.2
-
9
-
-
0034662157
-
The in vivo kinetics of tissue factor messenger RNA expression during human endotoxemia: relationship with activation of coagulation
-
Franco RF, et al. 2000. The in vivo kinetics of tissue factor messenger RNA expression during human endotoxemia: relationship with activation of coagulation. Blood 96:554-559.
-
(2000)
Blood
, vol.96
, pp. 554-559
-
-
Franco, R.F.1
-
10
-
-
0024292694
-
The molecular basis of blood coagulation
-
Furie B, Furie BC. 1988. The molecular basis of blood coagulation. Cell 53:505-518.
-
(1988)
Cell
, vol.53
, pp. 505-518
-
-
Furie, B.1
Furie, B.C.2
-
11
-
-
0025874052
-
Factor XI activation in a revised model of blood coagulation
-
Gailani D, Broze GJ, Jr. 1991. Factor XI activation in a revised model of blood coagulation. Science 253:909-912.
-
(1991)
Science
, vol.253
, pp. 909-912
-
-
Gailani, D.1
Broze Jr., G.J.2
-
12
-
-
0030916451
-
A murine model of factor XI deficiency. Blood Coagul
-
Gailani D, Lasky NM, Broze GJ, Jr. 1997. A murine model of factor XI deficiency. Blood Coagul. Fibrinolysis 8:134-144.
-
(1997)
Fibrinolysis
, vol.8
, pp. 134-144
-
-
Gailani, D.1
Lasky, N.M.2
Broze Jr., G.J.3
-
13
-
-
34250170510
-
The intrinsic pathway of coagulation: a target for treating thromboembolic disease?
-
Gailani D, Renne T. 2007. The intrinsic pathway of coagulation: a target for treating thromboembolic disease? J. Thromb. Haemost. 5:1106-1112.
-
(2007)
J. Thromb. Haemost.
, vol.5
, pp. 1106-1112
-
-
Gailani, D.1
Renne, T.2
-
14
-
-
0029986326
-
Inhibition of factor XII in septic baboons attenuates the activation of complement and fibrinolytic systems and reduces the release of interleukin-6 and neutrophil elastase
-
Jansen PM, et al. 1996. Inhibition of factor XII in septic baboons attenuates the activation of complement and fibrinolytic systems and reduces the release of interleukin-6 and neutrophil elastase. Blood 87:2337-2344.
-
(1996)
Blood
, vol.87
, pp. 2337-2344
-
-
Jansen, P.M.1
-
15
-
-
0037451170
-
Fibrin-mediated protection against infection-stimulated immunopathology
-
Johnson LL, Berggren KN, Szaba FM, Chen W, Smiley ST. 2003. Fibrin-mediated protection against infection-stimulated immunopathology. J. Exp. Med. 197:801-806.
-
(2003)
J. Exp. Med.
, vol.197
, pp. 801-806
-
-
Johnson, L.L.1
Berggren, K.N.2
Szaba, F.M.3
Chen, W.4
Smiley, S.T.5
-
16
-
-
34948866150
-
Endotoxemia and sepsis mortality reduction by non-anticoagulant activated protein C
-
Kerschen EJ, et al. 2007. Endotoxemia and sepsis mortality reduction by non-anticoagulant activated protein C. J. Exp. Med. 204:2439-2448.
-
(2007)
J. Exp. Med.
, vol.204
, pp. 2439-2448
-
-
Kerschen, E.J.1
-
17
-
-
1842600276
-
Universal changes in biomarkers of coagulation and inflammation occur in patients with severe sepsis, regardless of causative micro-organism
-
Kinasewitz GT, et al. 2004. Universal changes in biomarkers of coagulation and inflammation occur in patients with severe sepsis, regardless of causative micro-organism. Crit. Care 8:R82-R90.
-
(2004)
Crit. Care
, vol.8
-
-
Kinasewitz, G.T.1
-
18
-
-
55249103671
-
Activated protein C in sepsis: a critical review
-
Levi M. 2008. Activated protein C in sepsis: a critical review. Curr. Opin. Hematol. 15:481-486.
-
(2008)
Curr. Opin. Hematol.
, vol.15
, pp. 481-486
-
-
Levi, M.1
-
19
-
-
34548214668
-
Disseminated intravascular coagulation
-
Levi M. 2007. Disseminated intravascular coagulation. Crit. Care Med. 35:2191-2195.
-
(2007)
Crit. Care Med.
, vol.35
, pp. 2191-2195
-
-
Levi, M.1
-
20
-
-
1842478877
-
Coagulation in sepsis: all bugs bite equally
-
Levi M, Van Der Poll T. 2004. Coagulation in sepsis: all bugs bite equally. Crit. Care 8:99-100.
-
(2004)
Crit. Care
, vol.8
, pp. 99-100
-
-
Levi, M.1
Van Der Poll, T.2
-
23
-
-
0032212326
-
Activation of clotting factor XI without detectable contact activation in experimental human endotoxemia
-
Minnema MC, et al. 1998. Activation of clotting factor XI without detectable contact activation in experimental human endotoxemia. Blood 92:3294-3301.
-
(1998)
Blood
, vol.92
, pp. 3294-3301
-
-
Minnema, M.C.1
-
24
-
-
77953779759
-
What has been learnt from the thrombin-activatable fibrinolysis inhibitor-deficient mouse?
-
Morser J, Gabazza EC, Myles T, Leung LL. 2010. What has been learnt from the thrombin-activatable fibrinolysis inhibitor-deficient mouse? J. Thromb. Haemost. 8:868-876.
-
(2010)
J. Thromb. Haemost.
, vol.8
, pp. 868-876
-
-
Morser, J.1
Gabazza, E.C.2
Myles, T.3
Leung, L.L.4
-
25
-
-
21544436571
-
Infection-stimulated fibrin deposition controls hemorrhage and limits hepatic bacterial growth during listeriosis
-
Mullarky IK, et al. 2005. Infection-stimulated fibrin deposition controls hemorrhage and limits hepatic bacterial growth during listeriosis. Infect. Immun. 73:3888-3895.
-
(2005)
Infect. Immun.
, vol.73
, pp. 3888-3895
-
-
Mullarky, I.K.1
-
26
-
-
0025788582
-
Activation of human blood coagulation factor XI independent of factor XII. sFactor XI is activated by thrombin and factor XIa in the presence of negatively charged surfaces
-
Naito K, Fujikawa K. 1991. Activation of human blood coagulation factor XI independent of factor XII. Factor XI is activated by thrombin and factor XIa in the presence of negatively charged surfaces. J. Biol. Chem. 266:7353-7358.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 7353-7358
-
-
Naito, K.1
Fujikawa, K.2
-
27
-
-
77951205291
-
Contact system activation in severe infectious diseases
-
Oehmcke S, Herwald H. 2010. Contact system activation in severe infectious diseases. J. Mol. Med. 88:121-126.
-
(2010)
J. Mol. Med.
, vol.88
, pp. 121-126
-
-
Oehmcke, S.1
Herwald, H.2
-
28
-
-
67651113977
-
Treatment of invasive streptococcal infection with a peptide derived from human high-molecular weight kininogen
-
Oehmcke S, et al. 2009. Treatment of invasive streptococcal infection with a peptide derived from human high-molecular weight kininogen. Blood 114:444-451.
-
(2009)
Blood
, vol.114
, pp. 444-451
-
-
Oehmcke, S.1
-
29
-
-
5044222206
-
Immune responses to Listeria monocytogenes
-
Pamer EG. 2004. Immune responses to Listeria monocytogenes. Nat. Rev. Immunol. 4:812-823.
-
(2004)
Nat. Rev. Immunol.
, vol.4
, pp. 812-823
-
-
Pamer, E.G.1
-
30
-
-
77949263041
-
Cellular sources of tissue factor in endotoxemia and sepsis
-
Pawlinski R, Mackman N. 2010. Cellular sources of tissue factor in endotoxemia and sepsis. Thromb. Res. 125(Suppl. 1):S70-S73.
-
(2010)
Thromb. Res.
, vol.125
, Issue.1
-
-
Pawlinski, R.1
Mackman, N.2
-
31
-
-
0027469403
-
The contact system contributes to hypotension but not disseminated intravascular coagulation in lethal bacteremia. In vivo use of a monoclonal anti-factor XII antibody to block contact activation in baboons
-
Pixley RA, et al. 1993. The contact system contributes to hypotension but not disseminated intravascular coagulation in lethal bacteremia. In vivo use of a monoclonal anti-factor XII antibody to block contact activation in baboons. J. Clin. Invest. 91:61-68.
-
(1993)
J. Clin. Invest.
, vol.91
, pp. 61-68
-
-
Pixley, R.A.1
-
32
-
-
67849119604
-
Factor XI deficiency in animal models
-
Renne T, et al. 2009. Factor XI deficiency in animal models. J. Thromb. Haemost. 7(Suppl. 1):79-83.
-
(2009)
J. Thromb. Haemost.
, vol.7
, Issue.1
, pp. 79-83
-
-
Renne, T.1
-
34
-
-
0037036069
-
Activation of endothelial cell protease activated receptor 1 by the protein C pathway
-
Riewald M, Petrovan RJ, Donner A, Mueller BM, Ruf W. 2002. Activation of endothelial cell protease activated receptor 1 by the protein C pathway. Science 296:1880-1882.
-
(2002)
Science
, vol.296
, pp. 1880-1882
-
-
Riewald, M.1
Petrovan, R.J.2
Donner, A.3
Mueller, B.M.4
Ruf, W.5
-
35
-
-
67849097372
-
Factor XI deficiency in humans
-
Seligsohn U. 2009. Factor XI deficiency in humans. J. Thromb. Haemost. 7(Suppl. 1):84-87.
-
(2009)
J. Thromb. Haemost.
, vol.7
, Issue.1
, pp. 84-87
-
-
Seligsohn, U.1
-
36
-
-
79751504193
-
The pathogenesis of sepsis
-
Stearns-Kurosawa DJ, Osuchowski MF, Valentine C, Kurosawa S, Remick DG. 2011. The pathogenesis of sepsis. Annu. Rev. Pathol. 6:19-48.
-
(2011)
Annu. Rev. Pathol.
, vol.6
, pp. 19-48
-
-
Stearns-Kurosawa, D.J.1
Osuchowski, M.F.2
Valentine, C.3
Kurosawa, S.4
Remick, D.G.5
-
37
-
-
0029147959
-
Resolution of spontaneous bleeding events but failure of pregnancy in fibrinogen-deficient mice
-
Suh TT, et al. 1995. Resolution of spontaneous bleeding events but failure of pregnancy in fibrinogen-deficient mice. Genes Dev. 9:2020-2033.
-
(1995)
Genes Dev.
, vol.9
, pp. 2020-2033
-
-
Suh, T.T.1
-
38
-
-
0034307654
-
Modulation of hemostatic mechanisms in bacterial infectious diseases
-
Tapper H, Herwald H. 2000. Modulation of hemostatic mechanisms in bacterial infectious diseases. Blood 96:2329-2337.
-
(2000)
Blood
, vol.96
, pp. 2329-2337
-
-
Tapper, H.1
Herwald, H.2
-
39
-
-
33644511050
-
Tissue factor in hemostasis and thrombosis
-
Tilley R, Mackman N. 2006. Tissue factor in hemostasis and thrombosis. Semin. Thromb. Hemost. 32:5-10.
-
(2006)
Semin. Thromb. Hemost.
, vol.32
, pp. 5-10
-
-
Tilley, R.1
Mackman, N.2
-
40
-
-
47649108101
-
Survival advantage of coagulation factor XIdeficient mice during peritoneal sepsis
-
Tucker EI, et al. 2008. Survival advantage of coagulation factor XIdeficient mice during peritoneal sepsis. J. Infect. Dis. 198:271-274.
-
(2008)
J. Infect. Dis.
, vol.198
, pp. 271-274
-
-
Tucker, E.I.1
-
41
-
-
0035009042
-
Activation of coagulation factor XI, without detectable contact activation in dengue haemorrhagic fever
-
van Gorp EC, et al. 2001. Activation of coagulation factor XI, without detectable contact activation in dengue haemorrhagic fever. Br. J. Haematol. 113:94-99.
-
(2001)
Br. J. Haematol.
, vol.113
, pp. 94-99
-
-
van Gorp, E.C.1
-
42
-
-
0028843737
-
Feedback activation of factor XI by thrombin in plasma results in additional formation of thrombin that protects fibrin clots from fibrinolysis
-
von dem Borne PA, Meijers JC, Bouma BN. 1995. Feedback activation of factor XI by thrombin in plasma results in additional formation of thrombin that protects fibrin clots from fibrinolysis. Blood 86:3035-3042.
-
(1995)
Blood
, vol.86
, pp. 3035-3042
-
-
von dem Borne, P.A.1
Meijers, J.C.2
Bouma, B.N.3
-
43
-
-
33947104111
-
Beyond heparin and warfarin: the new generation of anticoagulants
-
Weitz JI, Linkins LA. 2007. Beyond heparin and warfarin: the new generation of anticoagulants. Expert Opin. Invest. Drugs 16:271-282.
-
(2007)
Expert Opin. Invest. Drugs
, vol.16
, pp. 271-282
-
-
Weitz, J.I.1
Linkins, L.A.2
-
44
-
-
0037083267
-
Listeria monocytogenes: clinical and experimental update
-
Wing EJ, Gregory SH. 2002. Listeria monocytogenes: clinical and experimental update. J. Infect. Dis. 185(Suppl. 1):S18-S24.
-
(2002)
J. Infect. Dis.
, vol.185
, Issue.1
-
-
Wing, E.J.1
Gregory, S.H.2
|