PARP inhibition in epithelial ovarian cancer: High hopes undergo a reality check

Oncology

Volumn 26, Issue 2, 2012, Pages 1-11

  Zorn, Kristin K ^a  

^a UNIVERSITY OF PITTSBURGH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; BEVACIZUMAB; CARBOPLATIN; CEDIRANIB; DOXORUBICIN; GEMCITABINE; INIPARIB; IRINOTECAN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NIRAPARIB; OLAPARIB; ORPHAN DRUG; PACLITAXEL; PLACEBO; PLATINUM COMPLEX; POLY(ADP RIBOSE)POLYMERASE 1; POLY(ADP RIBOSE)POLYMERASE 2; POLY(ADP RIBOSE)POLYMERASE INHIBITOR; RUCAPARIB; TEMOZOLOMIDE; UNCLASSIFIED DRUG; VELIPARIB;

ABSENCE OF SIDE EFFECTS; ANEMIA; BONE MARROW SUPPRESSION; BREAST CANCER; CANCER COMBINATION CHEMOTHERAPY; CELL DEATH; DIARRHEA; DNA STRAND BREAKAGE; DRUG DOSE COMPARISON; DRUG DOSE ESCALATION; DRUG FORMULATION; DRUG MECHANISM; DRUG MEGADOSE; DRUG SENSITIVITY; DRUG TOLERABILITY; ENZYME INHIBITION; EPITHELIAL OVARIAN CANCER; EPITHELIUM TUMOR; EXCISION REPAIR; FALLOPIAN TUBE CANCER; FATIGUE; FEBRILE NEUTROPENIA; GASTROINTESTINAL SYMPTOM; GENE MUTATION; GERMLINE MUTATION; HOMOLOGOUS RECOMBINATION; HUMAN; LOW DRUG DOSE; MAXIMUM TOLERATED DOSE; MONOTHERAPY; MULTIPLE CYCLE TREATMENT; NAUSEA; ONCOGENE; OVARY CANCER; PERITONEUM CANCER; PHASE 1 CLINICAL TRIAL (TOPIC); PHASE 2 CLINICAL TRIAL (TOPIC); PRIMARY PERITONEAL CANCER; PRIMARY TUMOR; PROGRESSION FREE SURVIVAL; RECOMMENDED DRUG DOSE; REVIEW; SOLID TUMOR; SOMATIC MUTATION; TRIPLE NEGATIVE BREAST CANCER; UTERINE TUBE TUMOR;

EID: 84857070593     PISSN: 08909091     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

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