GABA A receptor modulators from Chinese herbal medicines traditionally applied against insomnia and anxiety

Phytomedicine

Volumn 19, Issue 3-4, 2012, Pages 334-340

  Singhuber, Judith ^a   Baburin, Igor ^a   Kählig, Hanspeter ^a   Urban, Ernst ^a   Kopp, Brigitte ^a   Hering, Steffen ^a  

^a UNIVERSITY OF VIENNA   (Austria)

Author keywords

Atractylenolide; Atractylodes macrocephala; GABA A receptors; Positive allosteric modulation; Sesquiterpene lactones; Voltage clamp

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID A RECEPTOR ALPHA1BETA2GAMMA2S; ACETIC ACID ETHYL ESTER; ANXIOLYTIC AGENT; ATRACTYLENOLIDE; ATRACTYLODES MACROCEPHALA EXTRACT; BENZODIAZEPINE; CHLORIDE; METHANOL; PETROLEUM ETHER; RECOMBINANT RECEPTOR; SEDATIVE AGENT; SESQUITERPENE LACTONE DERIVATIVE; UNCLASSIFIED DRUG; WATER;

ANXIETY; ARTICLE; ATRACTYLODES; ATRACTYLODES MACROCEPHALA; BINDING SITE; CHINESE MEDICINE; CHLORIDE CURRENT; CONTROLLED STUDY; DRUG ACTIVITY; DRUG POTENCY; FRACTIONATION; INSOMNIA; MICROELECTRODE; NONHUMAN; OOCYTE; PRIORITY JOURNAL; RHIZOME; VOLTAGE CLAMP; XENOPUS LAEVIS;

ACETATES; ALKANES; ALLOSTERIC REGULATION; ANIMALS; ANTI-ANXIETY AGENTS; ANXIETY; BENZODIAZEPINES; BINDING SITES; CHEMICAL FRACTIONATION; DRUGS, CHINESE HERBAL; GABA AGONISTS; HYPNOTICS AND SEDATIVES; LACTONES; METHANOL; OOCYTES; PATCH-CLAMP TECHNIQUES; RECEPTORS, GABA-A; RECOMBINANT PROTEINS; RHIZOME; SESQUITERPENES; SLEEP INITIATION AND MAINTENANCE DISORDERS; WATER; XENOPUS LAEVIS;

ATRACTYLODES MACROCEPHALA; XENOPUS LAEVIS;

EID: 84857045369     PISSN: 09447113     EISSN: 1618095X     Source Type: Journal    
DOI: 10.1016/j.phymed.2011.10.009     Document Type: Article

References (38)

1. I. Baburin, S. Khom, E. Timin, A. Hohaus, W. Sieghart, and S. Hering Estimating the efficiency of benzodiazepines on GABA(A) receptors comprising gamma1 or gamma2 subunits Br. J. Pharmacol. 155 2008 424 433
2. D. Bensky, S. Clavey, and E. Stoeger Chinese Herbal Medicine: Materia Medica 2006 Eastland Press Seattle, WA
3. A.J. Boileau, T. Li, C. Benkwitz, C. Czajkowski, and R.A. Pearce Effects of [gamma]2S subunit incorporation on GABAA receptor macroscopic kinetics Neuropharmacology 44 2003 1003 1012 (Pubitemid 36570424)
4. C.A. Bourke, G.R. Stevens, and M.J. Carrigan Locomotor effects in sheep of alkaloids identified in Australian Tribulus terrestris Aust. Vet. J. 69 1992 163 165
5. E.L. Campbell, M. Chebib, and G.A. Johnston The dietary flavonoids apigenin and (-)-epigallocatechin gallate enhance the positive modulation by diazepam of the activation by GABA of recombinant GABA(A) receptors Biochem. Pharmacol. 68 2004 1631 1638 (Pubitemid 39286467)
6. L.C. Chen, I.C. Chen, B.R. Wang, and C.H. Shao Drug-use pattern of Chinese herbal medicines in insomnia: a 4-year survey in Taiwan J. Clin. Pharm. Ther. 34 2009 555 560
7. Z.L. Chen The Acetylenes from Atractylodes macrocephala Planta Med. 53 1987 493 494
8. Z.L. Chen, W.Y. Cao, G.X. Zhou, and M. Wichtl A sesquiterpene lactam from Artractylodes macrocephala Phytochemistry 45 1997 765 767 (Pubitemid 27248695)
9. H.-Y. Ding, M.-Y. Liu, W.-L. Chang, and H.-C. Lin New sesquiterpenoids from the rhizomes of Atractylodes macrocephala Chinese Pharm. J. (Taipei, Taiwan) 57 2005 37 42 (Pubitemid 43074382)
10. H. Dong, L. He, M. Huang, and Y. Dong Anti-inflammatory components isolated from Atractylodes macrocephala Koidz Nat. Prod. Res. 22 2008 1418 1427
11. K. Endo, T. Taguchi, F. Taguchi, H. Hikino, J. Yamahara, and H. Fujimura Sesquiterpenoids 55 anti-inflammatory principles of Atractylodes rhizomes Chem. Pharm. Bull. 27 1979 2954 2958 (Pubitemid 10145388)
12. C.-H. Hempen A Materia Medica for Chinese Medicine 2007 Elsevier Munich, Germany
13. H. Hikino, Y. Hikino, and I. Yosioka Studies on the constituents of Atractylodes. IX. Structure and autooxidation of atractylon Chem. Pharm. Bull. 12 1964 755 760
14. K.C. Huang The Pharmacology of Chinese Herbs 1999 CRC Press Boca Raton, US
15. G.A.R. Johnston, J.R. Hanrahan, M. Chebib, R.K. Duke, K.N. Mewett, and S.J. Enna Modulation of Ionotropic GABA Receptors by Natural Products of Plant Origin. Adv. Pharmacol. 2006 Elsevier San Diego, CA pp. 285-316
16. T.F. Kang, S.J. Jeong, N.Y. Kim, R. Higuchi, and Y.C. Kim Sedative activity of two flavonol glycosides isolated from the flowers of Albizzia julibrissin J. Ethnopharmacol. 71 2000 321 323 (Pubitemid 30440685)
17. A receptors: molecular mechanism and subunit specificity Neuropharmacology 53 2007 178 187 (Pubitemid 47125958)
18. A receptors containing gamma1 subunits Mol. Pharmacol. 69 2006 640 649 (Pubitemid 43121961)
19. W.K. Kim, J.W. Jung, N.Y. Ahn, H.R. Oh, B.K. Lee, J.K. Oh, J.H. Cheong, H.S. Chun, and J.H. Ryu Anxiolytic-like effects of extracts from Albizzia julibrissin bark in the elevated plus-maze in rats Life Sci. 75 2004 2787 2795 (Pubitemid 39349265)
20. J.C. Lee, K.Y. Lee, Y.O. Son, K.C. Choi, J. Kim, S.H. Kim, G.H. Chung, and Y.S. Jang Stimulating effects on mouse splenocytes of glycoproteins from rhe herbal medicine Atractylodes macrocephala Koidz Phytomedicine 14 2007 390 395 (Pubitemid 46818011)
21. C. Li, L. He, and T. Deng Pharmacokinetics and tissue distribution of atractylenolide III in rats Zhongyaocai 29 2006 807 809
22. Z. Lin, D. Zhu, Y. Yan, and B. Yu Neuroprotection by herbal formula FBD and its active compounds Pharm. Biol. 47 2009 608 614
23. A receptors Trends Neurosci. 27 2004 569 575 (Pubitemid 39149827)
24. H. Moehler GABAA receptor diversity and pharmacology Cell Tissue Res. 326 2006 505 516
25. E. Okuyama, H. Ebihara, H. Takeuchi, and M. Yamazaki Adenosine, the anxiolytic-like principle of the Arillus of Euphoria longana Planta Med. 65 1999 115 119 (Pubitemid 29138141)
26. R.W. Olsen, and W. Sieghart GABAA receptors: subtypes provide diversity of function and pharmacology Neuropharmacology 56 2009 141 148
27. T. Roth Insomnia: definition, prevalence, etiology, and consequences J. Clin. Sleep Med. 3 2007 7 10
28. J.J. Shan, and G.Y. Tian Studies on physico-chemical properties and hypoglycemic activity of complex polysaccharide AMP-B from Atractylodes macrocephala Koidz Yaoxue Xuebao 38 2003 438 441
29. J.M. Somers, E.M. Goldner, P. Waraich, and L. Hsu Prevalence and incidence studies of anxiety disorders: a systematic review of the literature Can. J. Psychiatry 51 2006 100 113
30. E. Stahl-Biskup, and A.-K. Drogen fifth ed. W. Blaschek, R. Hänsel, K. Keller, J. Reichling, H. Rimpler, G. Schneider, Hagers Handbuch der Pharmazeutischen Praxis, vol. 2 1998 Springer Berlin, Heidelberg, Germany 224 227
31. Y. Sugimoto, S. Furutani, A. Itoh, T. Tanahashi, H. Nakajima, H. Oshiro, S. Sun, and J. Yamada Effects of extracts and neferine from the embryo of Nelumbo nucifera seeds on the central nervous system Phytomedicine 15 2008 1117 1124
32. A receptors by valerian extracts is related to the content of valerenic acid Planta Med. 74 2008 19 24 (Pubitemid 351251378)
33. H. Wagner, and R. Bauer Chinese Drug Monographs And Analysis. Rhizoma Atractylodis Macrocephalae (Baizhu) 1997 Verlag für ganzheitzliche Medizin Dr. Erich Wühr Kotzing, Germany
34. C.C. Wang, S.Y. Lin, H.C. Cheng, and W.C. Hou Pro-oxidant and cytotoxic activities of atractylenolide I in human promyeloleukemic HL-60 cells Food Chem. Toxicol. 44 2006 1308 1315
35. J. Yamahara, T. Sawada, T. Tani, T. Nishino, I. Kitagawa, and H. Fujimura Biologically active principles of crude drugs. Pharmacological evaluation of the crude drug "Zhu" Yakugaku Zasshi 97 1977 873 879 (Pubitemid 8182254)
36. J. Yang, J. Xu, L. Zhou, L. Huang, S. Yang, T. Xiong, and L. Dong Sedative-hypnotic effect of caulis Polygoni multiflori decoction Hua Xi Yi Ke Da Xue Xue Bao 21 1990 175 177
37. + currents in cells of human pregnant myometrial smooth muscles J. Huazhong Univ. Sci. Technol. Med. Sci. 28 2008 200 203
38. C. Zhao, and C. He Preparative isolation and purification of atractylon and atractylenoide III from the Chinese medicinal plant Atractylodes macroephala by high-speed counter-current chromatography J. Sep. Sci. 29 2006 1630 1636 (Pubitemid 44184060)