Increased incidence of anti-GBM disease in Fcgamma receptor 2b deficient mice, but not mice with conditional deletion of Fcgr2b on either B cells or myeloid cells alone

Molecular Immunology

Volumn 50, Issue 1-2, 2012, Pages 49-56

  Sharp, Phoebe E H ^a   Martin Ramirez, Javier ^b   Boross, Peter ^b,c   Mangsbo, Sara M ^b,d   Reynolds, John ^a   Moss, Jill ^a   Pusey, Charles D ^a   Cook, H Terence ^a   Tarzi, Ruth M ^a   Verbeek, J Sjef ^b  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^c UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^d UPPSALA UNIVERSITY   (Sweden)

Author keywords

Anti glomerular basement membrane antibody disease; Conditional gene deletion; Fcgamma receptor; Goodpasture's disease; Mouse

Indexed keywords

CD11B ANTIGEN; COLLAGEN TYPE 4; FC RECEPTOR IIB; GLOMERULUS BASEMENT MEMBRANE ANTIBODY; GLYCOPROTEIN P 15095;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY PRODUCTION; ARTICLE; B LYMPHOCYTE; BONE MARROW CELL; CELL INFILTRATION; CONTROLLED STUDY; DENDRITIC CELL; EMBRYO; FLOW CYTOMETRY; GENE DELETION; GENE SEQUENCE; GENETIC SUSCEPTIBILITY; GLOMERULUS BASEMENT MEMBRANE ANTIBODY DISEASE; HISTOPATHOLOGY; IMMUNOPATHOLOGY; IMMUNOREGULATION; KIDNEY DYSFUNCTION; KNOCKOUT MOUSE; MACROPHAGE; MALE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEINURIA; RAPIDLY PROGRESSIVE GLOMERULONEPHRITIS; SEQUENCE ANALYSIS; WILD TYPE;

ANIMALS; ANTI-GLOMERULAR BASEMENT MEMBRANE DISEASE; AUTOANTIGENS; B-LYMPHOCYTES; COLLAGEN TYPE IV; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; GLOMERULONEPHRITIS; IMMUNIZATION; IMMUNOGLOBULIN G; KIDNEY; MALE; MICE; MICE, 129 STRAIN; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROSCOPY, ELECTRON; MYELOID CELLS; RECEPTORS, IGG;

MUS;

EID: 84857038613     PISSN: 01615890     EISSN: 18729142     Source Type: Journal    
DOI: 10.1016/j.molimm.2011.12.007     Document Type: Article

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