Influence of vascular comorbidities on the antioxidant defense system in Alzheimers disease;Einfluss vaskulärer Komorbiditäten auf die antioxidative Abwehr bei Alzheimer-Demenz

Deutsche Medizinische Wochenschrift

Volumn 137, Issue 7, 2012, Pages 305-308

  Polidori, M C ^a,b   Stahl, W ^b   De Spirt, S ^b   Pientka, L ^a  

^a RUHR UNIVERSITY BOCHUM   (Germany)

^b Department of Orthopedic Surgery   (Germany)

Author keywords

Alzheimers disease; antioxidants; dementia; oxidative stress

Indexed keywords

ALPHA CAROTENE; ALPHA TOCOPHEROL; ANTIOXIDANT; BETA CAROTENE; BETA CRYPTOXANTHIN; LYCOPENE; RETINOL; TRACE ELEMENT; XANTHOPHYLL; ZEAXANTHIN;

ALZHEIMER DISEASE; ARTERIAL WALL THICKNESS; ARTICLE; ATHEROSCLEROSIS; CARDIOVASCULAR RISK; CLINICAL ARTICLE; COMMON CAROTID ARTERY; COMORBIDITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; NEUROPSYCHOLOGICAL TEST; NON INSULIN DEPENDENT DIABETES MELLITUS; VASCULAR DISEASE; VITAMIN BLOOD LEVEL;

AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; ANTIOXIDANTS; DIABETES MELLITUS, TYPE 2; FEMALE; HUMANS; MALE; MICRONUTRIENTS; NEUROPSYCHOLOGICAL TESTS; OXIDATIVE STRESS; RISK FACTORS; VASCULAR DISEASES; VITAMIN A;

EID: 84857029410     PISSN: 00120472     EISSN: 14394413     Source Type: Journal    
DOI: 10.1055/s-0031-1298883     Document Type: Article

References (24)

1. Altman R, Rutledge JC. The vascular contribution to Alzheimers Disease. Clin Sci (Lond): 2010; 119 407 421
2. Anlasik T, Sies H, Griffiths HR et al. Dietary habits are major determinants of the plasma antioxidant status in healthy elderly subjects. Br J Nutr: 2005; 94 639 642 (Pubitemid 41672365)
3. Dumont T, Lin MT, Beal MF. Mitochondria and antioxidant targeted therapeutic strategies for Alzheimer's disease. J Alzheimers Dis: 2010; 20 02 633 643
4. Folstein MF, Robins LN, Helzer JE. The Mini-Mental State Examination. Arch Gen Psychiatry: 1983; 40 812
5. Fratiglioni L, Mangialasche F, Qiu C. Brain aging: lessons from community studies. Nutr Rev: 2010; 68 02 119 127
6. Giacco F, Brownlee M. Oxidative stress and diabetic complications. Circ Res: 2010; 107 1058 1070
7. Harman D. The biologic clock. The mitochondria? J Am Geriatr Soc: 1972; 20 145 147
8. Jakob S, Haelender J. Molecular mechanisms involved in endothelial cell aging: role of telomerase reverse transcriptase. Z Gerontol Geriat: 2007; 40 334 338
9. Kalaria RN. Vascular basis for brain degeneration: faltering controls and risk factors for dementia. Nutr Rev: 2010; 68 02 74 87
10. Kalbe E, Kessler J, Calabrese P et al. DemTect: a new, sensitive cognitive screening test to support the diagnosis of mild cognitive impairment and early dementia. Int J Ger Psych: 2004; 19 136 143 (Pubitemid 38247848)
11. Li L, Smith A, Hagen TM et al. Vascular oxidative stress and inflammation increase with age: ameliorating effects of -lipoic acid supplementation. Ann NY Acad Sci: 2010; 1203 151 159
12. Mangialasche F, Polidori MC, Monastero R et al. Biomarkers of oxidative and nitrosative damage in Alzheimer's disease and mild cognitive impairment. Ageing Res Rev: 2009; 8 285 305
13. Mariani E, Polidori MC, Cherubini A et al. Oxidative stress in brain aging, neurodegenerative and vascular diseases: an overview. Chromatogr B Analyt Technol Biomed Life Sci: 2005; 827 65 75 (Pubitemid 41551598)
14. Mecocci P, Mariani E, Polidori MC et al. Antioxidant agents in Alzheimers disease. Centr Nerv Syst Ag Med Chem: 2008; 8 48 63
15. McKhann G, Drachman D, Folstein M et al. Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA work group under the auspices of Department of Health and Human Services Task Force on Alzheimer's disease. Neurology: 1984; 34 939 944 (Pubitemid 14076461)
16. Polidori MC, Mecocci P, Stahl W et al. Plasma levels of lipophilic antioxidants in very old patients with type 2 diabetes. Diab Met Res Rev: 2000; 16 15 19 (Pubitemid 30160612)
17. Polidori MC, Pratic D, Parente B et al. Elevated lipid peroxidation biomarkers and low antioxidant status in atherosclerotic patients with increased carotid or iliofemoral intima-media thickness. J Invest Med: 2007; 55 163 167 (Pubitemid 47492774)
18. Polidori MC, Pratic D, Mariani E et al. High fruit and vegetable intake, high antioxidant status and good cognitive performance are associated in healthy subjects. J Alzheimers Dis: 2009; 17 921 927
19. Polidori MC, Nelles G, Pientka L. Prevention of dementia: focus on lifestyle. Int J Alzheimers Dis: 2010; pii 393579
20. Shulman KI. Clock Drawing Test: is it the ideal cognitive test? Intern J Ger Psych: 2000; 15 548 561 (Pubitemid 30410000)
21. Sies H. Oxidative stress: introductory remarks. In: Sies H. Hrsg. Oxidative Stress. Orlando Academic Press: 1985
22. Sies H. Antioxidants in disease mechanisms and therapy. London: 1997
23. Stahl W, Sundquist AR, Hanusch M et al. Separation of -carotene and lycopene geometrical isomers in biological samples. Clin Chem: 1993; 39 810 814 (Pubitemid 23145670)
24. Stroppe G. Demenz. München Ernst Rheinardt Verlag: 2007