Artesunate/dihydroartemisinin pharmacokinetics in acute falciparum malaria in pregnancy: Absorption, bioavailability, disposition and disease effects

British Journal of Clinical Pharmacology

Volumn 73, Issue 3, 2012, Pages 467-477

  Mcgready, Rose ^a,b,c   Phyo, Aung Pyae ^a   Rijken, Marcus J ^a   Tarning, Joel ^b,c   Lindegardh, Niklas ^b,c   Hanpithakpon, Warunee ^b   Than, Hla Hla ^a   Hlaing, Nathar ^a   Zin, Naw Thida ^a   Singhasivanon, Pratap ^b   White, Nicholas J ^b,c   Nosten, François ^a,b,c  

^a SHOKLO MALARIA RESEARCH UNIT   (Thailand)

^b MAHIDOL UNIVERSITY   (Thailand)

^c UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Artesunate; Dihyroartemisinin; Malaria; Pharmacokinetics; Post partum; Pregnancy

Indexed keywords

ARTEMISININ DERIVATIVE; ARTESUNATE; DIHYROARTEMISININ; UNCLASSIFIED DRUG;

ADULT; ANEMIA; ANOREXIA; AREA UNDER THE CURVE; ARTHRALGIA; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; CROSSOVER PROCEDURE; DIZZINESS; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG DISPOSITION; DRUG DISTRIBUTION; DRUG EFFICACY; DRUG EXPOSURE; FATIGUE; FEMALE; HEADACHE; HEMATOCRIT; HUMAN; LIQUID CHROMATOGRAPHY; MALARIA FALCIPARUM; MASS SPECTROMETRY; PREGNANCY; PRIORITY JOURNAL; SIDE EFFECT;

ADOLESCENT; ADULT; ANTIMALARIALS; ARTEMISININS; BIOLOGICAL AVAILABILITY; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HUMANS; MALARIA, FALCIPARUM; METABOLIC CLEARANCE RATE; POSTPARTUM PERIOD; PREGNANCY; PREGNANCY COMPLICATIONS, PARASITIC; SEVERITY OF ILLNESS INDEX; YOUNG ADULT;

EID: 84857003505     PISSN: 03065251     EISSN: 13652125     Source Type: Journal    
DOI: 10.1111/j.1365-2125.2011.04103.x     Document Type: Article

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