-
1
-
-
0037025309
-
Crystal structure and biochemical characterization of human kallikrein 6 reveals that a trypsin-like kallikrein is expressed in the central nervous system
-
Bernett M.J., Blaber S.I., Scarisbrick I.A., Dhanarajan P., Thompson S.M., Blaber M. Crystal structure and biochemical characterization of human kallikrein 6 reveals that a trypsin-like kallikrein is expressed in the central nervous system. J. Biol. Chem. 2002, 277:24562-24570.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 24562-24570
-
-
Bernett, M.J.1
Blaber, S.I.2
Scarisbrick, I.A.3
Dhanarajan, P.4
Thompson, S.M.5
Blaber, M.6
-
2
-
-
3042750282
-
The tissue kallikrein family of serine proteases: functional roles in human disease and potential as clinical biomarkers
-
Clements J.A., Willemsen N.M., Myers S.A., Dong Y. The tissue kallikrein family of serine proteases: functional roles in human disease and potential as clinical biomarkers. Crit. Rev. Clin. Lab. Sci. 2004, 41:265-312.
-
(2004)
Crit. Rev. Clin. Lab. Sci.
, vol.41
, pp. 265-312
-
-
Clements, J.A.1
Willemsen, N.M.2
Myers, S.A.3
Dong, Y.4
-
3
-
-
33344457699
-
Human kallikrein 6 expression in salivary gland tumors
-
Darling M.R., Jackson-Boeters L., Daley T.D., Diamandis E.P. Human kallikrein 6 expression in salivary gland tumors. J. Histochem. Cytochem. 2006, 54:337-342.
-
(2006)
J. Histochem. Cytochem.
, vol.54
, pp. 337-342
-
-
Darling, M.R.1
Jackson-Boeters, L.2
Daley, T.D.3
Diamandis, E.P.4
-
4
-
-
0037445253
-
Human kallikrein 6 (hK6): a new potential serum biomarker for diagnosis and prognosis of ovarian carcinoma
-
Diamandis E.P., Scorilas A., Fracchioli S., Van Gramberen M., De Bruijn H., Henrik A., Soosaipillai A., Grass L., Yousef G.M., Stenman U.H., Massobrio M., Van Der Zee A.G., Vergote I., Katsaros D. Human kallikrein 6 (hK6): a new potential serum biomarker for diagnosis and prognosis of ovarian carcinoma. J. Clin. Oncol. 2003, 21:1035-1043.
-
(2003)
J. Clin. Oncol.
, vol.21
, pp. 1035-1043
-
-
Diamandis, E.P.1
Scorilas, A.2
Fracchioli, S.3
Van Gramberen, M.4
De Bruijn, H.5
Henrik, A.6
Soosaipillai, A.7
Grass, L.8
Yousef, G.M.9
Stenman, U.H.10
Massobrio, M.11
Van Der Zee, A.G.12
Vergote, I.13
Katsaros, D.14
-
5
-
-
0036320526
-
Human tissue kallikreins: a family of new cancer biomarkers
-
Diamandis E.P., Yousef G.M. Human tissue kallikreins: a family of new cancer biomarkers. Clin. Chem. 2002, 48:1198-1205.
-
(2002)
Clin. Chem.
, vol.48
, pp. 1198-1205
-
-
Diamandis, E.P.1
Yousef, G.M.2
-
6
-
-
0034543474
-
Human kallikrein 6 (zyme/protease M/neurosin): a new serum biomarker of ovarian carcinoma
-
Diamandis E.P., Yousef G.M., Soosaipillai A.R., Bunting P. Human kallikrein 6 (zyme/protease M/neurosin): a new serum biomarker of ovarian carcinoma. Clin. Biochem. 2000, 33:579-583.
-
(2000)
Clin. Biochem.
, vol.33
, pp. 579-583
-
-
Diamandis, E.P.1
Yousef, G.M.2
Soosaipillai, A.R.3
Bunting, P.4
-
7
-
-
54049150854
-
Utility of kallikrein-related peptidases (KLKs) as cancer biomarkers
-
Emami N., Diamandis E.P. Utility of kallikrein-related peptidases (KLKs) as cancer biomarkers. Clin. Chem. 2008, 54:1600-1607.
-
(2008)
Clin. Chem.
, vol.54
, pp. 1600-1607
-
-
Emami, N.1
Diamandis, E.P.2
-
8
-
-
47549105735
-
Kallikrein 6 is a mediator of K-RAS-dependent migration of colon carcinoma cells
-
Henkhaus R.S., Gerner E.W., Ignatenko N.A. Kallikrein 6 is a mediator of K-RAS-dependent migration of colon carcinoma cells. Biol. Chem. 2008, 389:757-764.
-
(2008)
Biol. Chem.
, vol.389
, pp. 757-764
-
-
Henkhaus, R.S.1
Gerner, E.W.2
Ignatenko, N.A.3
-
9
-
-
84856949151
-
Up-regulation and clinical significance of serine protease kallikrein 6 in colon cancer
-
Kim J.T., Song E.Y., Chung K.S., Kang M.A., Kim J.W., Kim S.J., Yeom Y.I., Kim J.H., Kim K.H., Lee H.G. Up-regulation and clinical significance of serine protease kallikrein 6 in colon cancer. Cancer 2010.
-
(2010)
Cancer
-
-
Kim, J.T.1
Song, E.Y.2
Chung, K.S.3
Kang, M.A.4
Kim, J.W.5
Kim, S.J.6
Yeom, Y.I.7
Kim, J.H.8
Kim, K.H.9
Lee, H.G.10
-
10
-
-
79958840876
-
Up-regulation and clinical significance of serine protease kallikrein 6 in colon cancer
-
Kim J.T., Song E.Y., Chung K.S., Kang M.A., Kim J.W., Kim S.J., Yeom Y.I., Kim J.H., Kim K.H., Lee H.G. Up-regulation and clinical significance of serine protease kallikrein 6 in colon cancer. Cancer 2011, 117:2608-2619.
-
(2011)
Cancer
, vol.117
, pp. 2608-2619
-
-
Kim, J.T.1
Song, E.Y.2
Chung, K.S.3
Kang, M.A.4
Kim, J.W.5
Kim, S.J.6
Yeom, Y.I.7
Kim, J.H.8
Kim, K.H.9
Lee, H.G.10
-
11
-
-
0029901712
-
Identification of a novel serine protease-like gene, the expression of which is down-regulated during breast cancer progression
-
Liu X.L., Wazer D.E., Watanabe K., Band V. Identification of a novel serine protease-like gene, the expression of which is down-regulated during breast cancer progression. Cancer Res. 1996, 56:3371-3379.
-
(1996)
Cancer Res.
, vol.56
, pp. 3371-3379
-
-
Liu, X.L.1
Wazer, D.E.2
Watanabe, K.3
Band, V.4
-
12
-
-
0037767804
-
Characterization of the enzymatic activity of human kallikrein 6: autoactivation, substrate specificity, and regulation by inhibitors
-
Magklara A., Mellati A.A., Wasney G.A., Little S.P., Sotiropoulou G., Becker G.W., Diamandis E.P. Characterization of the enzymatic activity of human kallikrein 6: autoactivation, substrate specificity, and regulation by inhibitors. Biochem. Biophys. Res. Commun. 2003, 307:948-955.
-
(2003)
Biochem. Biophys. Res. Commun.
, vol.307
, pp. 948-955
-
-
Magklara, A.1
Mellati, A.A.2
Wasney, G.A.3
Little, S.P.4
Sotiropoulou, G.5
Becker, G.W.6
Diamandis, E.P.7
-
13
-
-
77952487860
-
Prognostic value and biological role of the kallikrein-related peptidases in human malignancies
-
Mavridis K., Scorilas A. Prognostic value and biological role of the kallikrein-related peptidases in human malignancies. Future Oncol. 2010, 6:269-285.
-
(2010)
Future Oncol.
, vol.6
, pp. 269-285
-
-
Mavridis, K.1
Scorilas, A.2
-
14
-
-
17144391833
-
Clinical significance of human kallikrein gene 6 messenger RNA expression in colorectal cancer
-
Ogawa K., Utsunomiya T., Mimori K., Tanaka F., Inoue H., Nagahara H., Murayama S., Mori M. Clinical significance of human kallikrein gene 6 messenger RNA expression in colorectal cancer. Clin. Cancer Res. 2005, 11:2889-2893.
-
(2005)
Clin. Cancer Res.
, vol.11
, pp. 2889-2893
-
-
Ogawa, K.1
Utsunomiya, T.2
Mimori, K.3
Tanaka, F.4
Inoue, H.5
Nagahara, H.6
Murayama, S.7
Mori, M.8
-
15
-
-
2942650115
-
Cloning and characterization of novel isoforms of the human kallikrein 6 gene
-
Pampalakis G., Kurlender L., Diamandis E.P., Sotiropoulou G. Cloning and characterization of novel isoforms of the human kallikrein 6 gene. Biochem. Biophys. Res. Commun. 2004, 320:54-61.
-
(2004)
Biochem. Biophys. Res. Commun.
, vol.320
, pp. 54-61
-
-
Pampalakis, G.1
Kurlender, L.2
Diamandis, E.P.3
Sotiropoulou, G.4
-
16
-
-
65949090534
-
A tumor-protective role for human kallikrein-related peptidase 6 in breast cancer mediated by inhibition of epithelial-to-mesenchymal transition
-
Pampalakis G., Prosnikli E., Agalioti T., Vlahou A., Zoumpourlis V., Sotiropoulou G. A tumor-protective role for human kallikrein-related peptidase 6 in breast cancer mediated by inhibition of epithelial-to-mesenchymal transition. Cancer Res. 2009, 69:3779-3787.
-
(2009)
Cancer Res.
, vol.69
, pp. 3779-3787
-
-
Pampalakis, G.1
Prosnikli, E.2
Agalioti, T.3
Vlahou, A.4
Zoumpourlis, V.5
Sotiropoulou, G.6
-
17
-
-
33745667041
-
Multiple mechanisms underlie the aberrant expression of the human kallikrein 6 gene in breast cancer
-
Pampalakis G., Sotiropoulou G. Multiple mechanisms underlie the aberrant expression of the human kallikrein 6 gene in breast cancer. Biol. Chem. 2006, 387:773-782.
-
(2006)
Biol. Chem.
, vol.387
, pp. 773-782
-
-
Pampalakis, G.1
Sotiropoulou, G.2
-
18
-
-
0037740746
-
Immunohistochemical localization of human kallikreins 6 and 10 in pancreatic islets
-
Petraki C.D., Karavana V.N., Revelos K.I., Luo L.Y., Diamandis E.P. Immunohistochemical localization of human kallikreins 6 and 10 in pancreatic islets. Histochem. J. 2002, 34:313-322.
-
(2002)
Histochem. J.
, vol.34
, pp. 313-322
-
-
Petraki, C.D.1
Karavana, V.N.2
Revelos, K.I.3
Luo, L.Y.4
Diamandis, E.P.5
-
19
-
-
33745655393
-
Cellular distribution of human tissue kallikreins: immunohistochemical localization
-
Petraki C.D., Papanastasiou P.A., Karavana V.N., Diamandis E.P. Cellular distribution of human tissue kallikreins: immunohistochemical localization. Biol. Chem. 2006, 387:653-663.
-
(2006)
Biol. Chem.
, vol.387
, pp. 653-663
-
-
Petraki, C.D.1
Papanastasiou, P.A.2
Karavana, V.N.3
Diamandis, E.P.4
-
20
-
-
0037597389
-
Structure-function relationship in protein families
-
Wiley-liss Inc., New York, T.M. Devlin (Ed.)
-
Schultz R.M., Liebman M.N. Structure-function relationship in protein families. Textbook of Biochemistry with Clinical Correlations 1997, 1-2. Wiley-liss Inc., New York. T.M. Devlin (Ed.).
-
(1997)
Textbook of Biochemistry with Clinical Correlations
, pp. 1-2
-
-
Schultz, R.M.1
Liebman, M.N.2
-
21
-
-
33645458299
-
Serum human glandular kallikrein 2 (hK2) for distinguishing stage and grade of prostate cancer
-
Stephan C., Jung K., Nakamura T., Yousef G.M., Kristiansen G., Diamandis E.P. Serum human glandular kallikrein 2 (hK2) for distinguishing stage and grade of prostate cancer. Int. J. Urol. 2006, 13:238-243.
-
(2006)
Int. J. Urol.
, vol.13
, pp. 238-243
-
-
Stephan, C.1
Jung, K.2
Nakamura, T.3
Yousef, G.M.4
Kristiansen, G.5
Diamandis, E.P.6
-
22
-
-
33745645642
-
Kallikrein-related peptidase (KLK) family mRNA variants and protein isoforms in hormone-related cancers: do they have a function?
-
Tan O.L., Whitbread A.K., Clements J.A., Dong Y. Kallikrein-related peptidase (KLK) family mRNA variants and protein isoforms in hormone-related cancers: do they have a function?. Biol. Chem. 2006, 387:697-705.
-
(2006)
Biol. Chem.
, vol.387
, pp. 697-705
-
-
Tan, O.L.1
Whitbread, A.K.2
Clements, J.A.3
Dong, Y.4
-
23
-
-
77951484580
-
Dysregulation of kallikrein-related peptidases in renal cell carcinoma: potential targets of miRNAs
-
White N.M., Bui A., Mejia-Guerrero S., Chao J., Soosaipillai A., Youssef Y., Mankaruos M., Honey R.J., Stewart R., Pace K.T., Sugar L., Diamandis E.P., Dore J., Yousef G.M. Dysregulation of kallikrein-related peptidases in renal cell carcinoma: potential targets of miRNAs. Biol. Chem. 2010, 391:411-423.
-
(2010)
Biol. Chem.
, vol.391
, pp. 411-423
-
-
White, N.M.1
Bui, A.2
Mejia-Guerrero, S.3
Chao, J.4
Soosaipillai, A.5
Youssef, Y.6
Mankaruos, M.7
Honey, R.J.8
Stewart, R.9
Pace, K.T.10
Sugar, L.11
Diamandis, E.P.12
Dore, J.13
Yousef, G.M.14
-
24
-
-
11444269896
-
In silico analysis of the human kallikrein gene 6
-
Yousef G.M., Borgono C.A., White N.M., Robb J.D., Michael I.P., Oikonomopoulou K., Khan S., Diamandis E.P. In silico analysis of the human kallikrein gene 6. Tumour Biol. 2004, 25:282-289.
-
(2004)
Tumour Biol.
, vol.25
, pp. 282-289
-
-
Yousef, G.M.1
Borgono, C.A.2
White, N.M.3
Robb, J.D.4
Michael, I.P.5
Oikonomopoulou, K.6
Khan, S.7
Diamandis, E.P.8
-
25
-
-
0035018273
-
The new human tissue kallikrein gene family: structure, function, and association to disease
-
Yousef G.M., Diamandis E.P. The new human tissue kallikrein gene family: structure, function, and association to disease. Endocr. Rev. 2001, 22:184-204.
-
(2001)
Endocr. Rev.
, vol.22
, pp. 184-204
-
-
Yousef, G.M.1
Diamandis, E.P.2
-
26
-
-
0036562226
-
Expanded human tissue kallikrein family - a novel panel of cancer biomarkers
-
Yousef G.M., Diamandis E.P. Expanded human tissue kallikrein family - a novel panel of cancer biomarkers. Tumour Biol. 2002, 23:185-192.
-
(2002)
Tumour Biol.
, vol.23
, pp. 185-192
-
-
Yousef, G.M.1
Diamandis, E.P.2
-
27
-
-
0043264142
-
An overview of the kallikrein gene families in humans and other species: emerging candidate tumour markers
-
Yousef G.M., Diamandis E.P. An overview of the kallikrein gene families in humans and other species: emerging candidate tumour markers. Clin. Biochem. 2003, 36:443-452.
-
(2003)
Clin. Biochem.
, vol.36
, pp. 443-452
-
-
Yousef, G.M.1
Diamandis, E.P.2
-
28
-
-
77953674090
-
The human kallikrein gene family: new biomarkers for ovarian cancer
-
Yousef G.M., Diamandis E.P. The human kallikrein gene family: new biomarkers for ovarian cancer. Cancer Treat. Res. 2009, 149:165-187.
-
(2009)
Cancer Treat. Res.
, vol.149
, pp. 165-187
-
-
Yousef, G.M.1
Diamandis, E.P.2
-
29
-
-
1842509220
-
Sequence and evolutionary analysis of the human trypsin subfamily of serine peptidases
-
Yousef G.M., Elliott M.B., Kopolovic A.D., Serry E., Diamandis E.P. Sequence and evolutionary analysis of the human trypsin subfamily of serine peptidases. Biochim. Biophys. Acta 2004, 1698:77-86.
-
(2004)
Biochim. Biophys. Acta
, vol.1698
, pp. 77-86
-
-
Yousef, G.M.1
Elliott, M.B.2
Kopolovic, A.D.3
Serry, E.4
Diamandis, E.P.5
-
30
-
-
0033385499
-
Molecular characterization of zyme/protease M/neurosin (PRSS9), a hormonally regulated kallikrein-like serine protease
-
Yousef G.M., Luo L.Y., Scherer S.W., Sotiropoulou G., Diamandis E.P. Molecular characterization of zyme/protease M/neurosin (PRSS9), a hormonally regulated kallikrein-like serine protease. Genomics 1999, 62:251-259.
-
(1999)
Genomics
, vol.62
, pp. 251-259
-
-
Yousef, G.M.1
Luo, L.Y.2
Scherer, S.W.3
Sotiropoulou, G.4
Diamandis, E.P.5
-
31
-
-
23244459692
-
Human tissue kallikreins: from gene structure to function and clinical applications
-
Yousef G.M., Obiezu C.V., Luo L.Y., Magklara A., Borgono C.A., Kishi T., Memari N., Michael P., Sidiropoulos M., Kurlender L., Economopolou K., Kapadia C., Komatsu N., Petraki C., Elliott M., Scorilas A., Katsaros D., Levesque M.A., Diamandis E.P. Human tissue kallikreins: from gene structure to function and clinical applications. Adv. Clin. Chem. 2005, 39:11-79.
-
(2005)
Adv. Clin. Chem.
, vol.39
, pp. 11-79
-
-
Yousef, G.M.1
Obiezu, C.V.2
Luo, L.Y.3
Magklara, A.4
Borgono, C.A.5
Kishi, T.6
Memari, N.7
Michael, P.8
Sidiropoulos, M.9
Kurlender, L.10
Economopolou, K.11
Kapadia, C.12
Komatsu, N.13
Petraki, C.14
Elliott, M.15
Scorilas, A.16
Katsaros, D.17
Levesque, M.A.18
Diamandis, E.P.19
-
32
-
-
0042173181
-
Human kallikrein 5: a potential novel serum biomarker for breast and ovarian cancer
-
Yousef G.M., Polymeris M.E., Grass L., Soosaipillai A., Chan P.C., Scorilas A., Borgono C., Harbeck N., Schmalfeldt B., Dorn J., Schmitt M., Diamandis E.P. Human kallikrein 5: a potential novel serum biomarker for breast and ovarian cancer. Cancer Res. 2003, 63:3958-3965.
-
(2003)
Cancer Res.
, vol.63
, pp. 3958-3965
-
-
Yousef, G.M.1
Polymeris, M.E.2
Grass, L.3
Soosaipillai, A.4
Chan, P.C.5
Scorilas, A.6
Borgono, C.7
Harbeck, N.8
Schmalfeldt, B.9
Dorn, J.10
Schmitt, M.11
Diamandis, E.P.12
-
33
-
-
0842265103
-
Kallikrein gene downregulation in breast cancer
-
Yousef G.M., Yacoub G.M., Polymeris M.E., Popalis C., Soosaipillai A., Diamandis E.P. Kallikrein gene downregulation in breast cancer. Br. J. Cancer 2004, 90:167-172.
-
(2004)
Br. J. Cancer
, vol.90
, pp. 167-172
-
-
Yousef, G.M.1
Yacoub, G.M.2
Polymeris, M.E.3
Popalis, C.4
Soosaipillai, A.5
Diamandis, E.P.6
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