Cognitive symptoms are common in immune thrombocytopenia and associate with autonomic symptom burden

European Journal of Haematology

Volumn 88, Issue 3, 2012, Pages 224-228

  Frith, James ^a   Watson, Shirley ^b   Maggs, Paula H B Bolton ^c   Newton, Julia L ^a  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

^b ITP Support Association   (United Kingdom)

^c MANCHESTER ROYAL INFIRMARY   (United Kingdom)

Author keywords

Autonomic dysfunction; Cognition; Immune thrombocytopenia

Indexed keywords

ADULT; ARTICLE; AUTOIMMUNE THROMBOCYTOPENIA; AUTONOMIC DYSFUNCTION; CASE CONTROL STUDY; COGNITIVE DEFECT; COGNITIVE FAILURES QUESTIONNAIRE; COHORT ANALYSIS; COMPOSITE AUTONOMIC SYMPTOM SCALE; CONTROLLED STUDY; DISEASE SEVERITY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; QUESTIONNAIRE; RATING SCALE; SCORING SYSTEM; THROMBOCYTE COUNT;

ADULT; AGED; AUTONOMIC NERVOUS SYSTEM DISEASES; COGNITION DISORDERS; FEMALE; HUMANS; MALE; MIDDLE AGED; PREVALENCE; PURPURA, THROMBOCYTOPENIC, IDIOPATHIC; QUESTIONNAIRES;

EID: 84856975098     PISSN: 09024441     EISSN: 16000609     Source Type: Journal    
DOI: 10.1111/j.1600-0609.2011.01730.x     Document Type: Article

References (19)

1. Neunert C, Lim W, Crowther M, Cohen A, Solberg L, Crowther MA. The American Society of Hematology 2011 evidence-based practice guideline for immune thrombocytopenia. Blood 2011;117:4190-207.
2. Cines DB, Blanchette VS. Medical progress: immune thrombocytopenic purpura. N Engl J Med 2002;346:995-1008.
3. Nugent DJ, McMillan R, Nichol JL, Slichter SJ. Pathogenesis of chronic immune thrombocytopenic purpura: increase platelet destruction and/or decreased platelet production. Br J Haematol 2009;146:585-96.
4. Cines DB, Bussel JB. How I treat idiopathic thrombocytopenic purpura (ITP). Blood 2005;106:2244-51.
5. Mathias SD, Gao SK, Miller KL, et al. Impact of chronic immune thrombocytopenic purpura on health-related quality of life" a conceptual model" starting with the patient perspective. Health Qual Life Outcomes 2008;6:13.
6. Newton JL, Reese JA, Watson SI, Vesely SK, Bolton-Maggs PHB, George JN, Terrell DR. Fatigue in adult patients with primary immune thrombocytopenia. Eur J Haematol 2011;86:420-9.
7. Newton JL, Hollingsworth K, Taylor R, et al. Cognitive impairment in primary biliary cirrhosis; symptom impact and potential aetiology. Hepatology 2008;48:541-9.
8. Costigan A, Elliott C, McDonald C, Newton JL. Orthostatic symptoms predict functional capacity in Chronic Fatigue Syndrome implications for management. QJM 2010;103:589-95.
9. Newton JL. Liver disease as a risk factor for cognitive decline and dementia: an under-recognized issue reply. Hepatology 2009;49:698.
10. Zuccala G, Onder G, Pedone C, Carosella L, Pahor M, Bernabei R, Hypotension and cognitive impairment: selective association in patients with heart failure. Neurology 2001;57:1980-92.
11. Glynn R, Beckett LA, Hebert LE, Morris MC, Scherr PA, Evans DA. Current and remote blood pressure and cognitive decline. J Am Med Assoc 1999;281:438-45.
12. Kenny RA, Ballard C. Neurocardiovascular instability in cognitive impairment and dementia. Ann N Y Acad Sci 2002;977:183-95.
13. Matsubayashi K, Okumiya K, Wada T, Osaki Y, Fujisawa M, Doi Y, Ozawa T. Postural dysregulation in systolic blood pressure is associated with worsened scoring on neurobehavioral function tests and leukoaraiosis in the older elderly living in a community. Stroke 1997;28:2169-73.
14. Polvikoski TK, Perry R, Miller V, Kenny RA. Carotid Sinus Hypersensitivity associated with focal alpha-synucleinopathy in the autonomic nervous system. J Neurol Neurosurg Psychiatry 2006;77:1064-6.
15. Suarez GA, Opfer-Gehrking TL, Offord KP, Atkinson EJ, O'Brien PC, Low PA. The Autonomic Symptom Profile: a new instrument to assess autonomic symptoms. Neurology 1999;52:523-8.
16. Newton JL, Okonkwo O, Sutcliffe K, Seth A, Shin J, Jones DEJ. Symptoms of autonomic dysfunction in chronic fatigue syndrome. QJM 2007;100:519-26.
17. Broadbent DE, Cooper PF, FitzGerald P, Parkes KR. The Cognitive Failures Questionnaire (CFQ) and its correlates. Br J Clin Psychol 1982;21:1-16.
18. Rast P, Zimprich D, Van Boxtel M, Jolles J. Factor structure and measurement invariance of the Cognitive Failures Questionnaire across the adult life span. Assessment 2009;16:145-58.
19. Wagle AC, Berrios GE, Ho L. The Cognitive Failures Questionnaire in psychiatry. Compr Psychiatry 1999;40:478-84.