Protective effect of rutin and naringin on sperm quality in streptozotocin (STZ) induced type 1 diabetic rats

Iranian Journal of Pharmaceutical Research

Volumn 10, Issue 3, 2011, Pages 585-596

  Akondi, Raju Butchi ^a   Kumar, Phani ^a   Annapurna, Akula ^a   Pujari, Manasa ^a  

^a ANDHRA UNIVERSITY   (India)

Author keywords

Male infertility; Naringin; Oxidative stress; Rutin; Type 1 diabetes

Indexed keywords

AURANTIIN; CATALASE; GLUCOSE; INSULIN; MALONALDEHYDE; RUTOSIDE; STREPTOZOCIN; SUPEROXIDE DISMUTASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CELL VIABILITY; COMPARATIVE EFFECTIVENESS; CONTROLLED STUDY; DIABETES CONTROL; DRUG EFFICACY; ENZYME ACTIVATION; ENZYME REPRESSION; GLUCOSE BLOOD LEVEL; GLYCEMIC CONTROL; HISTOPATHOLOGY; INSULIN DEPENDENT DIABETES MELLITUS; INSULIN TREATMENT; LIPID PEROXIDATION; MALE; MALE GENITAL TRACT PARAMETERS; NONHUMAN; OXIDATIVE STRESS; PROTEIN CONTENT; RAT; SPERMATOZOON COUNT; SPERMATOZOON LIFESPAN; SPERMATOZOON MOTILITY; STREPTOZOCIN DIABETES; TESTIS; TISSUE LEVEL;

EID: 84856970419     PISSN: 17350328     EISSN: 17266890     Source Type: Journal    
DOI: None     Document Type: Article

References (49)

1. Hakeem P, Sani HA and Noor MM. Effects of Gynura procumbens extract and glibenclamide on sperm quality and specific activity of testicular lactate dehydrogenase in streptozotocin - induced diabetic rats. Malaysian J. Biochemistry and Molecular biology. (2008) 16: 10-14.
2. Amaral S, Moreno AJ, Santos MS, Seiça R and Ramalho-Santos J. Effects of hyperglycemia on sperm and testicular cells of goto-kakizaki and streptozotocin-treated rat models for diabetes. Theriogenology (2006) 66: 2056-2067
3. Kartikeya Makker, Ashok Agarwal and Rakesh Sharma. Oxidative stress and male infertility.Indian J. Med. Res. (2009) 129: 357-367.
4. Griesmacher A, Kindhauser M, Andert SE, Schreiner W, Toma C. Enhanced serum levels of thiobarbituric acid reactive substances in diabetic mellitus. Am. J. Med. (1995) 98: 469-75.
5. Murray FT, Cameron DF and Orth JM. Gonadal dysfunction in the spontaneously diabetic BB rat. Metabolism (1983) 32 Suppl: 141-147.
6. Aitken RJ, Clarkson JS and Fishel S. Generation of reactive oxygen species, lipid peroxidation, and human sperm function. Biol Reprod (1989) 41: 183-97.
7. Aitken J, Krausz C and Buckingham D. Relationships between biochemical markers for residual sperm cytoplasm, reactive oxygen species generation, and the presence of leukocytes and precursor germ cells in human sperm suspensions. Mol. Reprod Dev. (1994) 39: 268-79.
8. Agarwal A, Ikemoto I and Loughlin KR. Relationship of sperm parameters with levels of reactive oxygen species in semen specimens. J. Urol (1994) 152: 107-10.
9. Suleiman SA, Ali ME, Zaki ZM, el-Malik EM and Nasr MA. Lipid peroxidation and human sperm motility: protective role of vitamin E. J. Androl (1996) 17: 530-7.
10. Armstrong JS, Rajasekaran M, Chamulitrat W Gatti P, Hellstrom WJ and Sikka SC. Characterization of reactive oxygen species induced effects on human spermatozoa movement and energy metabolism. Free Radic Biol. Med. (1999) 26: 869-80.
11. Park NC, Park HJ, Lee KM, Shin DG. Free radical scavenger effect of rebamipide in sperm processing and cryopreservation. Asian J. Androl (2003) 5: 195-201.
12. Sikka SC. Role of oxidative stress and antioxidants in andrology and assisted reproductive technology. J Androl (2004) 25: 5-18.
13. Aybek H, Aybek Z, Rota S Sen N and Akbulut M. The effects of diabetes mellitus, age, and vitamin E on testicular oxidative stress. Fertil Steril (2008) 90:755-60.
14. Sakkas D, Moffatt O, Manicardi GC, Mariethoz E, Tarozzi N and Bizzaro D. Nature of DNA damage in ejaculated human spermatozoa and the possible involvement of apoptosis. Biol Reprod (2002) 66: 1061-7.
15. Paasch U, Sharma RK, Gupta AK, Grunewald S, Mascha EJ, Thomas AJ Jr, Glander HJ and Agarwal A. Cryopreservation and thawing is associated with varying extent of activation of apoptotic machinery in subsets of ejaculated human spermatozoa. Biol Reprod (2004) 71: 1828-37.
16. Cande C, Cecconi F, Dessen P and Kroemer G. Apoptosis-inducing factor (AIF): key to the conserved caspase-independent pathways of cell death? J. Cell Sci. (2002) 115: 4727-34.
17. Lenzi A, Lombardo F, Gandini L, Alfano P and Dondero F. Computer assisted sperm motility analysis at the moment of induced pregnancy during gonadotropin treatment for hypogonadotropic hypogonadism. J. Endocrinol Invest. (1993) 16: 683-6.
18. Evans JL, Goldfine ID, Maddux BA and Grodsky GM. Oxidative stress and stress activated signaling pathways: A unifying hypothesis of type 2 diabetes. Endo Rev (2002) 23: 599-622.
19. Taepongsorat L, Tangpraprutgul P, Kitana N and Malaivijitnond S. Stimulating effects of Qercetin on sperm quality and reproductive organs in adult male rats. Asian J. Androl (2008) 10: 249-258
20. Ohkawa and Ohishi N. Yagi K: Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem. (1979) 95: 391-398
21. Fridovich I: superoxide dismutase. Adv Enzymal. (1974) 41: 35-97.
22. Aebi H. Catalase in-vitro. Methods Enzymol. (1984) 105: 121-126.
23. Lowry OH, Rosebrough NJ, Farr AL and Randall RJ. Protein measurement with folin phenol reagent. J. Biol Chem. (1951) 193: 265-275
24. Zem Janis, R. collection and evaluation of semen. In diagnostic and therapeutic technique in animal reproduction, 2nd edition, the Williams and wilkikins comp. Baltimore. 1970
25. World health organization. WHO laboratory manual for human semen and semen-cervical mucus interaction, 2nd edition, Cambridge university press, 1985
26. Raji YUS, Udoh OO, Mewoyeka, Ononye FC and Bolarinwa AF. Implication of endocrine malfunction in male infertility efficacy of Azadiraktha Indica extract in rats. Afr. Med. Med. Sci. (2003) 32: 159-165
27. Sozmen EY, Sozmen B, Delen Y and Onat T. Catalase/superoxide dismutase (SOD) and catalase/paraoxonase (PON) ratios may implicate poor glycemic control. Arch Med Res (2001) 4: 283-7.
28. Annunziata L, Domenico F and Pietro T. Glyco-oxidation in diabetes and related diseases. Clin Chim Acta (2005) 2: 236-50.
29. Koksal IT, Usta M, Orhan I, Abbasoglu S and Kadioglu A. Potential role of reactive oxygen species on testicular pathology associated with infertility. Asian J. Androl (2003) 5: 95-9.
30. De Lamirande E and Gagnon C. Impact of reactive oxygen species on spermatozoa:a balancing act between beneficial and detrimental effects. Hum. Reprod (1995) 10 Suppl: 15-21.
31. Tavridou A, Unwin NC, Laker MF, White M and Alberti GK. Serum concentrations of vitamin A and E in impaired glucose tolerance. Clin. Chim. Acta. (1997) 266: 129-40.
32. Mamdouh M. Ali, Monira A, Abd El Kader. The influence of naringin on the oxidative state of rats with streptozotocin-induced acute hyperglycaemia. (2004) 59: 726-733.
33. Annapurna A, Reddy CS, Akondi RB and Rao SR. Cardioprotective actions of two bioflavonoids, qurecetin and rutin, in experimental myocardial infarction in both normal and streptozotocin-induced type I diabetic rats. J. Pharm. Pharmacology (2009) 61: 1365-1374.
34. Cazarolli LH, Zanatta L, Jorge AP, de Sousa E, Horst H, Woehl VM, Pizzolatti MG, Szpoganicz B and Silva FR. Follow-up studies on glycosylated flavonoids and their complexes with vanadium: Their anti-hyperglycemic potential role in diabetes. Chemico-BiologicalInteractions. (2006) 1633: 177-191.
35. P Stanley Mainzen Prince and N Kamalakkannan P. Rutin improves glucose homeostasis in streptozotocin diabetic tissues by altering glycolytic and gluconeogenic enzymes. J. Biochem. Mol. Toxico. (2006) 20: 96-102.
36. Sexton WJ and Jarow JP. Effect of Diabetes mellitus upon male reproductive function. Urology (1997) 49: 508-513.
37. Ballester J, Munoz MC and Dominguez J. Insulin-dependent diabetes affects testicular function by FSH- and LH-linked mechanisms. J. Androl. (2004) 25: 706-719.
38. Shuk-mei ho; viccionet and yum. In-vitro and in-vivo inhibition of nuclear type II estrogen binding sites in the dorsolateral prostate of noble rats. J. steroid biochemistry and molecular biology. (1993) 46: 489-495.
39. Desroches NK, McNiven MK, Foote KD and Richardson GF. The Effect of blueberry extracts and quercetin on capacitation status of stored boar sperm cell Preservation Technology. Fall (2005) 3: 165-168
40. Afanasev IB, Dorozhko AI, Brodskii AV, Kostyuk VA and Potapovitch AI. Chelating and free radical scavenging mechanisms of inhibitory action of Rutin and Qercetin in lipid peroxidation. Biochem. Pharmacol. (1989) 38: 1763-69.
41. Negre-Salvayre A, Affany A and Hariton CR. Additional antilipoperoxidant activites of alpha-tocopherol and ascorbic acid on membrane like systems are potentiated by rutin. Pharmacol. (1992) 42: 262-72.
42. Jeon SM, Bok SH, Jang MK, Kim YH, Nam KT, Jeong TS, Park YB and Choi MS. Comparison of antioxidant effects of naringin and probucol in cholesterol-fed rabbits. Clin. Chim. Acta. (2002) 317: 181-190.
43. Ali MM and El Kader MA. The influence of naringin on the oxidative state of rats with streptozotocin-induced acute hyperglycaemia. Z Naturforsch C (2004) 59: 726-733.
44. Jagetia GC, Venkatesha VA and Koti Reddy T. Naringin, a citrus flavonone, protects against radiation-induced chromosome damage in mouse bone marrow. Mutagenesis. (2003) 18: 337-343.
45. Jungsook Cho. Antioxidant and neuroprotective effects of hesperidin and its aglycone hesperetin. Archives of Pharmacal Res. (2006) 29: 699-706
46. Joghataie MT, Roghani M, Negahdar F and Hashemi L. Neuroprotective effect of caffeine in an early model of Parkinson's disease in rat: behavioral and histochemical evidence. Iranian J. Pharm. Res. (2004) 3: 80-80
47. Laight DW, Carrier MJ and Anggard EE. Antioxidants, diabetes and endothelial dysfunction. Cardiovascular Res. (2000) 47:457-464
48. Escobar JA, Rubio MA and Lissi EA. SOD and catalase inactivation by singlet oxygen and peroxyl radical. Free Rad. Boil. Med. (1996) 20: 285-290.
49. Rajnarayana K, SripalReddy M, Chaluvadi M and Krishna DR. Bioflavonoids classification, pharmacological, biochemical effects and therapeutic potential. Indian J. Pharmaco. (2001)33: 2-16.