Cardiac and vascular responses to thigh cuffs and respiratory maneuvers on crewmembers of the International Space Station

Journal of Applied Physiology

Volumn 112, Issue 3, 2012, Pages 454-462

  Hamilton, Douglas R ^a   Sargsyan, Ashot E ^a   Garcia, Kathleen ^a   Ebert, Douglas J ^a   Whitson, Peggy A ^b   Feiveson, Alan H ^b   Alferova, Irina V ^c   Dulchavsky, Scott A ^d   Matveev, Vladimir P ^e   Bogomolov, Valery V ^e   Duncan, J Michael ^b  

^a WYLE LABORATORIES   (United States)

^b NASA JOHNSON SPACE CENTER   (United States)

^c INSTITUTE OF BIOMEDICAL PROBLEMS   (Russian Federation)

^d HENRY FORD HOSPITAL   (United States)

^e Yuri A Gagarin Cosmonaut Training Center   (Russian Federation)

Author keywords

Astronaut; Cardiac function; Echocardiography; Microgravity; Occlusion cuffs

Indexed keywords

ADAPTATION; CARDIOVASCULAR SYSTEM; ECHOGRAPHY; HEMODYNAMICS; HUMAN; METHODOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; RESPIRATORY SYSTEM; REVIEW; SPACE FLIGHT; THIGH; VASCULARIZATION; WEIGHTLESSNESS;

ADAPTATION, PHYSIOLOGICAL; CARDIOVASCULAR SYSTEM; HEMODYNAMICS; HUMANS; RESPIRATORY SYSTEM; SPACE FLIGHT; THIGH; WEIGHTLESSNESS; WEIGHTLESSNESS COUNTERMEASURES; WEIGHTLESSNESS SIMULATION;

EID: 84856925409     PISSN: 87507587     EISSN: 15221601     Source Type: Journal    
DOI: 10.1152/japplphysiol.00557.2011     Document Type: Review

References (54)

1. Agid R, Farb RI, Willinsky RA, Mikulis DJ, Tomlinson G. Idiopathic intracranial hypertension: the validity of cross-sectional neuroimaging signs. Neuroradiology 48: 521-527, 2006. (Pubitemid 44165286)
2. American Registry for Diagnostic Medical Sonography. ARDMS (Online). http://www.ardms.org [October 29, 2011].
3. Arbeille P, Diridillou S, Herault S, Fomina G, Roumy J, Alferova I. Effect of the thigh-cuffs on the carotid artery diameter jugular vein section and facial skin edema: HDT study. J Gravit Physiol 6: 39-40, 1999.
4. Arbeille P, Fomina G, Pottier JM, Achaibou F, Kotovskaya A. Influence of the thigh cuffs countermeasure on the cardiovascular adaptation to 0 g (14 and 21 day Mir spaceflights). J Gravit Physiol 2: 9-10, 1995.
5. Arbeille P, Fomina G, Pottier JM, Bystrov V, Patat F, Kokova N, Strogonova L, Pourcelot L, Atkov O, Guell A. Cardiovascular disturbances induced by a 25 days spaceflight and a one month head down tilt. Physiologist 34: 151-152, 1991.
6. Arbeille P, Gaffney FA, Beck L, Coulon J, Porcher M, Blomqvist CG. Effect of microgravity on renal and femoral flows during LBNP and intravenous saline load. J Gravit Physiol 3: 91-92, 1996.
7. Arbeille P, Herault S, Fomina G, Roumy J, Alferova I, Gharib C. Influences of thigh cuffs on the cardiovascular system during 7-day head-down bed rest. J Appl Physiol 87: 2168-2176, 1999.
8. Atkov OY, Bednenko VS, Fomina GA. Ultrasound techniques in space medicine. Aviat Space Environ Med 58: 69-73, 1987.
9. Benjamini Y, Yekutieli D. The control of the false discovery rate in multiple testing under dependency. Ann Statistics 29: 1165-1188, 2001. (Pubitemid 33575263)
10. Blomqvist CG. Cardiovascular adaptation to weightlessness. Med Sci Sports Exerc 15: 428-431, 1983. (Pubitemid 14239240)
11. Buckey JC, Gaffney FA, Lane LD, Levine BD, Watenpaugh DE, Wright SJ, Yancy CW, Meyer DM, Blomqvist CG. Central venous pressure in space. J Appl Physiol 81: 19-25, 1996. (Pubitemid 26255488)
12. Buckey JC, Goble RL, Blomqvist CG. A new device for continuous ambulatory central venous pressure measurement. Med Instrum 21: 238-243, 1987. (Pubitemid 18603885)
13. Buckey JC, Peshock RM, Blomqvist CG. Deep venous contribution to hydrostatic blood volume change in the human leg. Am J Cardiol 62: 449-453, 1988.
14. Bungo MW, Charles JB, Johnson PC. Cardiovascular deconditioning during space flight and the use of saline as a countermeasure to orthostatic intolerance. Aviat Space Environ Med 56: 985-990, 1985. (Pubitemid 15249393)
15. Chiao L, Sharipov S, Sargsyan AE, Melton S, Hamilton DR, McFarlin K, Dulchavsky SA. Ocular examination for trauma; clinical ultrasound aboard the International Space Station. J Trauma 58: 885-889, 2005. (Pubitemid 40776886)
16. Diridollou S, Maillet A, Pavy-Le Traon A, Louisy F, Black D, Berson M, Gregoire JM, Gall Y, Arbeille P. Use of thigh pressure cuffs to modulate simulated microgravity-induced changes in the skin measured with high-resolution B-scan ultrasound. Eur J Ultrasound 13: 215-226, 2001. (Pubitemid 32549783)
17. Fincke EM, Padalka G, Lee D, van Holsbeeck M, Sargsyan AE, Hamilton DR, Martin D, Melton SL, McFarlin K, Dulchavsky SA. Evaluation of shoulder integrity in space: first report of musculoskeletal US on the International Space Station. Radiology 234: 319-322, 2005. (Pubitemid 40139894)
18. Foale CM, Kaleri AY, Sargsyan AE, Hamilton DR, Melton S, Martin D, Dulchavsky SA. Diagnostic instrumentation aboard ISS: just-in-time training for non-physician crewmembers. Aviat Space Environ Med 76: 594-598, 2005. (Pubitemid 40770733)
19. Foldager N, Andersen TA, Jessen FB, Ellegaard P, Stadeager C, Videbaek R, Norsk P. Central venous pressure in humans during microgravity. J Appl Physiol 81: 408-412, 1996. (Pubitemid 26255537)
20. Fritsch-Yelle JM, Convertino VA, Schlegel TT. Acute manipulations of plasma volume alter arterial pressure responses during Valsalva maneuver. J Appl Physiol 86: 1852-1857, 1999. (Pubitemid 29275559)
21. Fujimoto N, Shibata S, Hastings JL, Carrick-Ranson GC, Bhella PS, Palmer MD, Fu Q, Levine BD. Effects of pericardial constraint and ventricular interaction on left ventricular hemodynamics in the unloaded heart. Am J Physiol Heart Circ Physiol 300: H1688-H1695, 2011.
22. Gazenko OG, Schulzhenko EB, Grigoriev AI, Atkov OYU, Egorov AD. Review of basic medical results of the Salyut-7-Soyuz-T 8-month manned flight. Acta Astronaut 17: 155-160, 1988. (Pubitemid 18597954)
23. Gazenko OG, Shumakov VI, Kakurin LI, Katkov VE, Chestukhin VV, Nikolayenko EM, Gvozdev SV, Rumyantsev VV, Vasilyev VK. Effects of various countermeasures against the adverse effects of weightlessness on central circulation in the healthy man. Aviat Space Environ Med 53: 523-530, 1982. (Pubitemid 12014592)
24. Geeraerts T, Newcombe VF, Coles JP, Abate MG, Perkes IE, Hutchinson PJ, Outtrim JG, Chatfield DA, Menon DK. Use of T2-weighted magnetic resonance imaging of the optic nerve sheath to detect raised intracranial pressure. Crit Care 12: R114, 2008.
25. Gopalakrishnan R, Genc KO, Rice AJ, Lee SM, Evans HJ, Maender CC, Ilaslan H, Cavanagh PR. Muscle volume, strength, endurance, and exercise loads during 6-month missions in space. Aviat Space Environ Med 81: 91-102, 2010.
26. Haddad F, Hunt SA, Rosenthal DN, Murphy DJ. Right ventricular function in cardiovascular disease, part I: anatomy, physiology, aging, and functional assessment of the right ventricle. Circulation 117: 1436-1448, 2008. (Pubitemid 351501496)
27. Hamilton DR, Dani RS, Semlacher RA, Smith ER, Kieser TM, Tyberg JV. Right atrial and right ventricular transmural pressures in dogs and humans. Effects of the pericardium. Circulation 90: 2492-2500, 1994. (Pubitemid 24354338)
28. Hamilton DR, deVries G, Tyberg JV. Static and dynamic operating characteristics of a pericardial balloon. J Appl Physiol 90: 1481-1488, 2001. (Pubitemid 32220935)
29. Hamilton DR, Sargsyan AE, Martin D, Garcia K, Melton S, Dulchavsky SA. On-orbit prospective echocardiography on International Space Station crew. Echocardiog J 28: 491-501, 2011.
30. Herault S, Fomina G, Alferova I, Kotovskaya A, Poliakov V, Arbeille P. Cardiac, arterial and venous adaptation to weightlessness during 6-month MIR spaceflights with and without thigh cuffs (bracelets). Eur J Appl Physiol 81: 384-90, 2000. (Pubitemid 30189961)
31. Hinghofer-Szalkay H, Haditsch B, Loder I, Pilz K, Rossler A, Jezova D. Head down tilt at -6 degrees to -24 degrees can neutralize the cardiovascular effects of LBNP at -15 or -35 mmHg. Aviat Space Environ Med 75: 947-951, 2004. (Pubitemid 39435184)
32. Hurrell DG, Nishimura RA, Ilstrup DM, Appleton CP. Utility of preload alteration in assessment of left ventricular filling pressure by Doppler echocardiography: a simultaneous catheterization and Doppler echocardiographic study. J Am Coll Cardiol 30: 459-467, 1997. (Pubitemid 27339326)
33. Katkov VE, Chestukhin VV, Nikolaenko EM, Gvozdev SV, Rumiantsev VV. [Effect of negative pressure and occluding cuffs on the intravascular pressure in the lower extremity of the healthy human being]. Kosm Biol Aviakosm Med 15: 9-12, 1981.
34. Kirsch KA, Rocker L, Gauer OH, Krause R, Leach C, Wicke HJ, Landry R. Venous pressure in man during weightlessness. Science 225: 218-219, 1984. (Pubitemid 14079872)
35. Lindgren KN, Kraft D, Ballard RE, Tucker A, Hargens AR. Venoconstrictive thigh cuffs impede fluid shifts during simulated microgravity. Aviat Space Environ Med 69: 1052-1058, 1998. (Pubitemid 28492471)
36. Mader TH, Gibson CR, Pass AF, Kramer LA, Lee AG, Fogarty J, Tarver WJ, Dervay JP, Hamilton DR, Sargsyan A, Phillips JL, Tran D, Lipsky W, Choi J, Stern C, Kuyumjian R, Polk JD. Optic disc edema, globe flattening, choroidal folds, and hyperopic shifts observed in astronauts after long-duration space flight. Ophthalmology 118: 2058-2069, 2011.
37. Matsnev EI, Yakovleva IY, Tarasov IK, Alekseev VN, Kornilova LN, Mateev AD, Gorgiladze GI. Space motion sickness: phenomenology, countermeasures, and mechanisms. Aviat Space Environ Med 54: 312-317, 1983. (Pubitemid 13037821)
38. Mehta NR, Jones L, Kraut MA, Melhem ER. Physiologic variations in dural venous sinus flow on phase-contrast MR imaging. Am J Roentgenol Radium Ther 175: 221-225, 2000. (Pubitemid 30415567)
39. Nagueh SF. Echocardiographic assessment of left ventricular relaxation and cardiac filling pressures. Curr Heart Fail Rep 6: 154-159, 2009.
40. a. National Board of Echocardiography. National Board of Echocardiography (Online). http://www.echoboards.org/ [October 29, 2011].
41. Olabi AA, Lawless HT, Hunter JB, Levitsky DA, Halpern BP. The effect of microgravity and space flight on the chemical senses. J Food Sci 67: 468-478, 2002. (Pubitemid 34294128)
42. Pasdeloup T, Mas M, Stevenin H. Remote assistance experiment during the manned space flight Altair. Acta Astronaut 36: 625-628, 1995.
43. Pottier JM, Patat F, Arbeille P, Pourcelot L, Massabuau P, Guell A, Gharib C. Cardiovascular system and microgravity simulation and inflight results. Acta Astronaut 13: 47-51, 1986. (Pubitemid 16492072)
44. Pourcelot L, Patat F, Defontaine M, Gregoire JM, Berson M. Microgravity. Ultrasound Med Biol 26, Suppl 1: S144-S146, 2000. (Pubitemid 30229974)
45. Pourcelot L, Pottier JM, Arbeille P, Patat F, Berson M, Roncin A, Le TC, Guell A, Gharib C. [Cardiovascular function in astronauts (Mission STG 51 G-June 1985)]. Bull Acad Natl Med 170: 341-344, 1986.
46. Sargsyan AE, Dulchavsky SA, Jones JA, Hamilton DR, Roden S, Melton S, Martin D, Garcia K, Duncan M. Abdominal imaging with ultrasound on the International Space Station. Aviat Space Environ Med 77th Annual Scientific Meetings, ASMA, Orlando FL: 2006.
47. Sargsyan AE, Hamilton DR, Jones JA, Melton S, Whitson PA, Kirkpatrick AW, Martin D, Dulchavsky SA. FAST at MACH 20: clinical ultrasound aboard the International Space Station. J Trauma 58: 35-39, 2005. (Pubitemid 40221730)
48. Schreiber SJ, Lambert UK, Doepp F, Valdueza JM. Effects of prolonged head-down tilt on internal jugular vein cross-sectional area. Br J Anaesth 89: 769-771, 2002. (Pubitemid 35277230)
49. a. Tei C, Dujardin KS, Hodge DO, Kyle RA, Tajik AJ, Seward JB. Doppler index combining systolic and diastolic myocardial performance: Clinical value in cardiac amyloidosis. J Am Coll Cardiol 27: 658-664, 1996. (Pubitemid 26288647)
50. Tei C, Nishimura RA, Seward JB, Tajik AJ. Noninvasive Dopplerderived myocardial performance index: correlation with simultaneous measurements of cardiac catheterization measurements. J Am Soc Echocardiogr 10: 169-178, 1997. (Pubitemid 127789844)
51. Thornton WE, Moore TP, Pool SL. Fluid shifts in weightlessness. Aviat Space Environ Med 58: 86-90, 1987.
52. Tomaselli CM, Kenney RA, Frey MA, Hoffler GW. Cardiovascular dynamics during the initial period of head-down tilt. Aviat Space Environ Med 58: 3-8, 1987. (Pubitemid 17002944)
53. Trappe S, Costill D, Gallagher P, Creer A, Peters JR, Evans H, Riley DA, Fitts RH. Exercise in space: human skeletal muscle after 6 months aboard the International Space Station. J Appl Physiol 106: 1159-1168, 2009.
54. Tyberg JV, Hamilton DR. Orthostatic hypotension and the role of changes in venous capacitance. Med Sci Sports Exerc 28: S29-S31, 1996. (Pubitemid 26353365)