Awareness in Alzheimer's disease and associated dementias: Theoretical framework and clinical implications

Aging and Mental Health

Volumn 15, Issue 8, 2011, Pages 936-944

  Clare, Linda ^a   Markova, Ivana S ^b   Roth, Ilona ^c   Morris, Robin G ^d  

^a BANGOR UNIVERSITY   (United Kingdom)

^b UNIVERSITY OF HULL   (United Kingdom)

^c OPEN UNIVERSITY   (United Kingdom)

^d KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Anosognosia; Denial; Insight; Metacognition; Self awareness

Indexed keywords

ALZHEIMER DISEASE; ARTICLE; AWARENESS; CAREGIVER; CONCEPT FORMATION; DENIAL; EDUCATION; HEALTH CARE DELIVERY; HUMAN; PATHOPHYSIOLOGY; PSYCHOLOGICAL ASPECT; RESEARCH; THEORETICAL MODEL; UNITED KINGDOM;

ALZHEIMER DISEASE; AWARENESS; CAREGIVERS; CONCEPT FORMATION; DELIVERY OF HEALTH CARE; DENIAL (PSYCHOLOGY); GREAT BRITAIN; HUMANS; MODELS, THEORETICAL; RESEARCH;

EID: 84856904046     PISSN: 13607863     EISSN: 13646915     Source Type: Journal    
DOI: 10.1080/13607863.2011.583630     Document Type: Article

References (48)

1. Aalten, P., van Valen, E., Clare, L., Kenny, G., & Verhey, F. (2005). Awareness in dementia: A review of clinical correlates. Aging and Mental Health, 9, 414-422. (Pubitemid 41097714)
2. Agnew, S.K., & Morris, R.G. (1998). The heterogeneity of anosognosia for memory impairment in Alzheimer's disease: A review of the literature and a proposed model. Aging and Mental Health, 2, 7-19. (Pubitemid 28118758)
3. Clare, L. (2004). The construction of awareness in early-stage Alzheimer's disease: A review of concepts and models. British Journal of Clinical Psychology, 43, 155-175. (Pubitemid 38923509)
4. Clare, L., Marková , I.S., Verhey, F., & Kenny, G. (2005). Awareness in dementia: A review of assessment methodsand measures. Aging and Mental Health, 9, 394-413. (Pubitemid 41097713)
5. Clare, L., Nelis, S.M., Martyr, A., Roberts, J., Whitaker, C.J., Markova, I.S., . . . , Morris, R.G. (2011). The influence of psychological, social and contextual factors on the expression and measurement of awareness in early-stage dementia: Testing a biopsychosocial model. International Journal of Geriatric Psychiatry (in press). doi: 10.1002/ gps.2705.
6. Clare, L., Rowlands, J., Bruce, E., Surr, C., & Downs, M. (2008). I don't do like I used to do: A grounded theory approach to conceptualising awareness in people with moderate to severe dementia living in long-term care. Social Science and Medicine, 66, 2366-2377. (Pubitemid 351608732)
7. Clare, L., Woods, R.T., Whitaker, R., Wilson, B.A., & Downs, M. (2010). Development of an awareness-based intervention to enhance quality of life in severe dementia: Trial platform. Trials, 11, 73.
8. Conway, M.A. (2005). Memory and the self. Journal of Memory and Language, 53, 594-628. (Pubitemid 41614853)
9. Damasio, A. (1999). The feeling of what happens: Body and emotion in the making of consciousness. New York, NY: Harcourt.
10. Davies, M., Davies, A.A., & Coltheart, M. (2005). Anosognosia and the two-factor theory of delusions. Mind and Language, 20, 209-236.
11. Gergen, K.J. (1984). Theory of the self: Impasse and evolution. In L. Berkowitz (Ed.), Advances in Experimental social psychology (Vol. 17, pp. 49-115). New York: Harcourt Brace Jovanovich.
12. Giovannetti, T., Libon, D.J., & Hart, T. (2002). Awareness of naturalistic action errors in dementia. Journal of the International Neuropsychological Society, 8, 633-644.
13. Glaser, B.G., & Strauss, A.L. (1965). Awareness of dying. Chicago, IL: Aldine.
14. Greenwald, A.G. (1980). The totalitarian ego. American Psychologist, 35, 603-618.
15. Hannesdottir, K., & Morris, R.G. (2007). Primary and secondary anosognosia for memory impairment in patients with Alzheimer's disease. Cortex, 43, 1020-1030. (Pubitemid 47520456)
16. Humphrey, N. (1986). The inner eye. London: Faber and Faber.
17. Klein, S.B., Cosmides, L., & Costabile, K.A. (2003). Preserved knowledge of self in a case of Alzheimer's dementia. Social Cognition, 21, 157-165. (Pubitemid 37417257)
18. Klein, S.B., German, T.P., Cosmides, L., & Gabriel, R. (2004). A theory of autobiographical memory: Necessary components and disorders resulting from their loss. Social Cognition, 22, 460-490. (Pubitemid 39648559)
19. Levine, B. (2004). Autobiographical memory and the self in time: Brain lesion effects, functional neuroanatomy, and the lifespan development. Brain and Cognition, 55, 54-68. (Pubitemid 38591430)
20. Lewis, M. (2003). The emergence of consciousness and its role in human development. Annals of the New York Academy of Science, 1001, 104-133.
21. Logsdon, R.G., Pike, K.C., McCurry, S.M., Hunter, P., Maher, J., Snyder, S., & Teri, L. (2010). Early-stage memory loss support groups: Outcomes from a randomized controlled clinical trial. Journal of Gerontology: Psychological Sciences, 65B, 691-697.
22. Magai, C., Cohen, C., Gomberg, D., Malatesta, C., & Culver, C. (1996). Emotional expression during mid- to late-stage dementia. International Psychogeriatrics, 8, 383-395. (Pubitemid 27067588)
23. Marková , I.S. (2005). Insight in psychiatry. Cambridge: Cambridge University Press.
24. Marková , I.S., Clare, L, Wang, M., Romero, B., & Kenny, G. (2005). Awareness in dementia: Conceptual issues. Aging and Mental Health, 9, 386-393. (Pubitemid 41097712)
25. McDaniel, K.D., Edland, S.D., Heyman, A., & the CERAD clinical investigators. (1995). Relationship between level of insight and severity of dementia in Alzheimer disease. Alzheimer Disease and Associated Disorders, 9, 101-104.
26. Morin, A. (2006). Levels of consciousness and self-awareness: A comparison and integration of various neurocognitive views. Consciousness and Cognition, 15, 358-371. (Pubitemid 43729555)
27. Morris, R., & Hannesdottir, K. (2004). Loss of 'awareness' in Alzheimer's disease. In R. Morris & J. Becker (Eds.), Cognitive neuropsychology of Alzheimer's disease (pp. 275-296). Oxford: Oxford University Press.
28. Natsoulas, T. (1997). Consciousness and self-awareness. Journal of Mind and Behavior, 18, 53-74.
29. Neisser, U. (1997). The roots of self-knowledge: Perceiving self, it, and thou. In J.G. Snodgrass & R.L. Thompson (Eds.), The self across psychology: Selfrecognition, self-awareness, and the self-concept (pp. 18-33). New York: Academy of Sciences.
30. Newen, A., & Vogeley, K. (2003). Self-representation: Searching for a neural signature of self-consciousness. Consciousness and Cognition, 12, 529-543. (Pubitemid 37491344)
31. Perner, J. (2000). Memory and theory of mind. In E. Tulving & F.I.M. Craik (Eds.), The Oxford handbook of memory (pp. 297-312). Oxford: Oxford University Press.
32. Phinney, A. (2002). Fluctuating awareness and the breakdown of the illness narrative in dementia. Dementia, 1,329-343.
33. Prigatano, G.P. (1999). Principles of neuropsychological rehabilitation. New York: Oxford University Press.
34. Salmon, E., Perani, D., Herholz, K., Maurique, P., Kalbe, E., Holthoff, V., . . . , Garraux, G. (2006). Neural correlates of anosognosia for cognitive impairment in Alzheimer's disease. Human Brain Mapping, 27, 588-597. (Pubitemid 44078930)
35. Samsonovich, A.V., & Ascoli, G.A. (2005). The conscious self: Ontology, epistemology and the mirror quest. Cortex, 41, 621-363.
36. Schooler, J.W. (2002). Re-representing consciousness: Dissociations between experience and meta-consciousness. Trends in Cognitive Sciences, 6, 339-344. (Pubitemid 34828312)
37. Shibata, K., Narumoto, J., Kitabayashi, Y., Ushijima, Y., & Fukui, K. (2008). Correlation between anosognosia and regional cerebral blood flow in Alzheimer's disease. Neuroscience Letters, 435, 7-10.
38. Stuss, D.T., Picton, T.W., & Alexander, M.P. (2001). Consciousness, self-awareness and the frontal lobes. In S. Salloway, P. Malloy, & J. Duffy (Eds.), The frontal lobes and neuropsychiatric illness (pp. 101-109).Washington, DC: American Psychiatric Press.
39. Tulving, E. (1985). Memory and consciousness. Canadian Psychology, 26, 1-12.
40. Tulving, E. (1993). Varieties of consciousness and levels of awareness in memory. In A. Baddeley & L. Weiskrantz (Eds.), Attention: Selection, awareness and control. A tribute to Donald Broadbent (pp. 283-299). Oxford: Oxford University Press.
41. Watkins, R., Cheston, R., Jones, K., & Gilliard, J. (2006). Coming out with Alzheimer's disease: Changes in awareness during a psychotherapy group for people with dementia. Aging and Mental Health, 10, 166-176. (Pubitemid 43355127)
42. Weinstein, E.A., Friedland, R.P., & Wagner, E.E. (1994). Denial/unawareness of impairment and symbolic behavior in Alzheimer's disease. Neuropsychiatry, Neuropsychology and Behavioral Neurology, 7, 176-184. (Pubitemid 24268941)
43. West, R.L., Dennehy-Basile, D., & Norris, M.P. (1996). Memory self-evaluation: The effects of age and experience. Aging, Neuropsychology and Cognition, 3, 67-83. (Pubitemid 26356344)
44. Whitlatch, C., Judge, K., Zarit, S.H., & Femia, E. (2006). Dyadic interventions for family caregivers and care receivers in early-stage dementia. The Gerontologist, 46, 688-694. (Pubitemid 44639847)
45. Wilson, T.D., & Dunn, E.W. (2004). Self-knowledge: Its limits, value and potential for improvement. Annual Review of Psychology, 55, 493-518.
46. Zelazo, P.D. (2004). The development of conscious control in childhood. Trends in Cognitive Sciences, 8, 12-17. (Pubitemid 38018894)
47. Zeman, A. (1997). Persistent vegetative state. The Lancet, 350, 795-799. (Pubitemid 27387217)
48. Zeman, A. (2001). Consciousness. Brain, 124, 1263-1289. (Pubitemid 32606089)