Low-density platelet populations demonstrate low in vivo activity in sporadic Alzheimer disease

Platelets

Volumn 23, Issue 2, 2012, Pages 116-120

  Jremo, P ^a   Milovanovic, M ^a   Buller, C ^a   Nilsson, S ^b   Winblad, B ^c  

^a VRINNEVI HOSPITAL   (Sweden)

^b LINKÖPING UNIVERSITY   (Sweden)

^c KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Dementia; Fibrinogen; Platelet heterogeneity; Platelet in vivo activation; Sporadic Alzheimer disease

Indexed keywords

FIBRINOGEN;

AGED; ALZHEIMER DISEASE; ARTICLE; CELL DENSITY; CELL POPULATION; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; IN VIVO STUDY; MALE; PRIORITY JOURNAL; THROMBOCYTE; THROMBOCYTE COUNT;

AGED; ALZHEIMER DISEASE; BLOOD PLATELETS; CASE-CONTROL STUDIES; FEMALE; FIBRINOGEN; HUMANS; MALE; PLATELET ACTIVATION;

EID: 84856860243     PISSN: 09537104     EISSN: 13691635     Source Type: Journal    
DOI: 10.3109/09537104.2011.593654     Document Type: Article

References (31)

1. Corash L, Costa JL, Shafer B, Donlon JA, Murphy D. Heterogeneity of human whole blood platelet subpopulations. III. Density-dependent differences in subcellular constituents. Blood 1984;64:185-193. (Pubitemid 14083874)
2. Karpatkin S, Charmatz A. Heterogeneity of human platelets. 3. Glycogen metabolism in platelets of different sizes. Br J Haematol 1970;19:135-143.
3. Polanowska-Grabowska R, Raha S, Gear AR. Adhesion efficiency, platelet density and size. Br J Haematol 1992;82:715-720. (Pubitemid 23011978)
4. Karpatkin S, Strick N. Heterogeneity of human platelets. V. Differences in glycolytic and related enzymes with possible relation to platelet age. J Clin Invest 1972;51:1235-1243.
5. Milovanovic M, Lysen J, Ramström S, Lindahl TL, Richter A, Järemo P. Identification of low-density platelet populations with increased reactivity and elevated alpha-granule content. Thromb Res 2003;111:75-80. (Pubitemid 37485929)
6. Milovanovic M, Lotfi K, Lindahl TL, Hallert C, Järemo P. Platelet density subpopulations in essential thrombocythemia and healthy volunteers. Pathophysiol Haemost Thromb 2010;37:35-42.
7. Järemo P, Sandberg-Gertzen H. Platelet density and size in inflammatory bowel disease. Thromb Haemost 1996;75:560-561. (Pubitemid 26138260)
8. Järemo P. Platelet density in essential thrombocythemia and polycythemia vera. Platelets 1999;10:61-63. (Pubitemid 29084387)
9. Järemo P, Lindahl TL, Lennmarken C, Forsgren H. The use of platelet density and volume measurements to estimate the severity of pre-eclampsia. Eur J Clin Invest 2000;30:1113-1118. (Pubitemid 32064061)
10. Järemo P, Milovanovic M, Nilsson S, Buller C, Post C and Winblad B. Alzheimer's disease is characterized by more low density erythrocytes with increased volume and enhanced/3-amyloid X-40 content. Journal of Internal Medicine 2011;270:489-492.
11. Gardella JE, Ghiso J, Gorgone GA, Marratta D, Kaplan AP, Frangione B, Gorevic PD. Intact Alzheimer amyloid precursor protein (APP) is present in platelet membranes and is encoded by platelet mRNA. Biochem Biophys Res Commun 1990;173:1292-1298.
12. Chen M, Inestrosa NC, Ross GS, Fernandez HL. Platelets are the primary source of amyloid beta-peptide in human blood. Biochem Biophys Res Commun 1995;213:96-103.
13. Valla J, Schneider L, Niedzielko T, Coon KD, Caselli R, Sabbagh MN, Ahern GL, Baxter L, Alexander G, Walker DG, et al. Impaired platelet mitochondrial activity in Alzheimer's disease and mild cognitive impairment. Mitochondrion 2006;6:323-330. (Pubitemid 44817367)
14. Baskin F, Rosenberg RN, Iyer L, Hynan L, Cullum CM. Platelet APP isoform ratios correlate with declining cognition in AD. Neurology 2000;54:1907-1909. (Pubitemid 30327110)
15. Borroni B, Colciaghi F, Corsini P, Akkawi N, Rozzini L, Del Zotto E, Talarico G, Cattabeni F, Lenzi GL, Di Luca M, et al. Early stages of probable Alzheimer disease are associated with changes in platelet amyloid precursor protein forms. Neurol Sci 2002;23: 207-210. (Pubitemid 36024562)
16. Liu HC, Wang HC, Ko SY, Wang PN, Chi CW, Hong CJ, Lin KN, Liu TY. Correlation between platelet amyloid precursor protein isoform ratio and cognition in Alzheimer's disease. J Alzheimers Dis 2007;11:77-84.
17. Bush AI, Martins RN, Rumble B, Moir R, Fuller S, Milward E, Currie J, Ames D, Weidemann A, Fischer P, et al. The amyloid precursor protein of Alzheimer's disease is released by human platelets. J Biol Chem 1990;265:15977-15983.
18. Casoli T, Di Stefano G, Giorgetti B, Grossi Y, Balietti M, Fattoretti P, Bertoni-Freddari C. Release of beta-amyloid from high-density platelets: Implications for Alzheimer's disease pathology. Ann N Y Acad Sci 2007;1096:170-178. (Pubitemid 47092510)
19. Adolfsson R, Gottfries CG, Oreland L, Wiberg A, Winblad B. Increased activity of brain and platelet monoamine oxidase in dementia of Alzheimer type. Life Sci 1980;27:1029-1034. (Pubitemid 11252511)
20. Laske C, Leyhe T, Stransky E, Eschweiler GW, Bueltmann A, Langer H, Stellos K, Gawaz M. Association of platelet-derived soluble glycoprotein VI in plasma with Alzheimer's disease. J Psychiatr Res 2008;42:746-751. (Pubitemid 351636099)
21. Stellos K, Panagiota V, Kögel A, Leyhe T, Gawaz M, Laske C. Predictive value of platelet activation for the rate of cognitive decline in Alzheimer's disease patients. J Cereb Blood Flow Metab 2010;30:1817-1820.
22. Ciabattoni G, Porreca E, Di Febbo C, Di Iorio A, Paganelli R, Bucciarelli T, Pescara L, Del Re L, Giusti C, Falco A, et al. Determinants of platelet activation in Alzheimer's disease. Neurobiol Aging 2007;28:336-342. (Pubitemid 46177381)
23. Dale GL. Coated-platelets: An emerging component of the procoagulant response. J Thromb Haemost 2005;3: 2185-2192. (Pubitemid 41727196)
24. Prodan CI, Szasz R, Vincent AS, Ross ED, Dale GL. Coated-platelets retain amyloid precursor protein on their surface. Platelets 2006;17:56-60. (Pubitemid 41759242)
25. Prodan CI, Ross ED, Vincent AS, Dale GL. Rate of progression in Alzheimer's disease correlates with coated-platelet levels-a longitudinal study. Transl Res 2008;152: 99-102.
26. Prodan CI, Ross ED, Stoner JA, Cowan LD, Vincent AS, Dale GL. Coated-platelet levels and progression from mild cognitive impairment to Alzheimer disease. Neurology 2011;76:247-252.
27. Järemo P. Computerised method for recording platelet density distribution. Eur J Haematol 1995;54:304-309.
28. Järemo P, Lindahl TL, Fransson SG, Richter A. Individual variations of platelet inhibition after loading doses of clopidogrel. J Int Med 2002;252:233-238.
29. Mangalpally KK, Siqueiros-Garcia A, Vaduganathan M, Dong JF, Kleiman NS, Guthikonda S. Platelet activation patterns in platelet size sub-populations: Differential responses to aspirin in vitro. J Thromb Thrombol 2010;30:251-262.
30. Shi C, Guo K, Yew DT, Yao Z, Forster EL, Wang H, Xu J. Effects of ageing and Alzheimer's disease on mitochondrial function of human platelets. Exp Gerontol 2008;43:589-594.
31. Pavlov PF, Wiehager B, Sakai J, Frykman S, Behbahani H, Winblad B, Ankarcrona M. Mitochondrial {gamma}-secre-tase participates in the metabolism of mitochondria-associated amyloid precursor protein. FASEB J 2011;25:78-88.